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FB:tefu
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | tefu ( synonyms: ATM, Atm, CG6535, Drosophila ATM, Tefu, ataxia telangiectasia mutated, ataxia telengiesctasia mutated, ataxia-telangiectasia mutated, atm, atm/tefu, dATM, tef ) | |
| Protein Name(s) | telomere fusion, | |
| External Links | ||
| FB | FBgn0045035 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000075 |
cell cycle checkpoint |
FB:FBrf0130073 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0000723 |
telomere maintenance |
FB:FBrf0180053 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000723 |
telomere maintenance |
FB:FBrf0191425 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0004672 |
protein kinase activity |
FB:FBrf0130073 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004672 |
protein kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0006348 |
chromatin silencing at telomere |
FB:FBrf0179362 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007093 |
mitotic cell cycle checkpoint |
FB:FBrf0204663 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003525 |
P |
From FB |
||
| GO:0007095 |
mitotic cell cycle G2/M transition DNA damage checkpoint |
FB:FBrf0212700 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0261530 |
P |
From FB |
||
| GO:0016233 |
telomere capping |
FB:FBrf0194855 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016310 |
phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0031572 |
G2/M transition DNA damage checkpoint |
FB:FBrf0190707 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045494 |
photoreceptor cell maintenance |
FB:FBrf0204663 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051276 |
chromosome organization |
FB:FBrf0180052 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051276 |
chromosome organization |
FB:FBrf0180053 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051276 |
chromosome organization |
FB:FBrf0180054 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051276 |
chromosome organization |
FB:FBrf0194855 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Sekelsky JJ et al. (2000) DNA repair in Drosophila: insights from the Drosophila genome sequence. J Cell Biol 150: F31-6 PubMed GONUTS page
- ↑ 2.0 2.1 Bi X et al. (2004) Telomere protection without a telomerase; the role of ATM and Mre11 in Drosophila telomere maintenance. Curr Biol 14: 1348-53 PubMed GONUTS page
- ↑ Bi X et al. (2005) Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance. Proc Natl Acad Sci U S A 102: 15167-72 PubMed GONUTS page
- ↑ 4.0 4.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ Oikemus SR et al. (2004) Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect. Genes Dev 18: 1850-61 PubMed GONUTS page
- ↑ 6.0 6.1 Rimkus SA et al. (2008) Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia. Genes Dev 22: 1205-20 PubMed GONUTS page
- ↑ Kondo S & Perrimon N (2011) A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint. Sci Signal 4: rs1 PubMed GONUTS page
- ↑ 8.0 8.1 Ciapponi L et al. (2006) The Drosophila Nbs protein functions in multiple pathways for the maintenance of genome stability. Genetics 173: 1447-54 PubMed GONUTS page
- ↑ Bi X et al. (2005) Drosophila ATM and Mre11 are essential for the G2/M checkpoint induced by low-dose irradiation. Genetics 171: 845-7 PubMed GONUTS page
- ↑ Silva E et al. (2004) ATM is required for telomere maintenance and chromosome stability during Drosophila development. Curr Biol 14: 1341-7 PubMed GONUTS page
- ↑ Song YH et al. (2004) The Drosophila ATM ortholog, dATM, mediates the response to ionizing radiation and to spontaneous DNA damage during development. Curr Biol 14: 1354-9 PubMed GONUTS page
