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FB:stau

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) stau ( synonyms: CG5753, Dmstau, STAU, STAUFEN, Stau, Stauf, Staufen, Stauffen, dStau )
Protein Name(s) staufen,
External Links
FB FBgn0003520

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000932

cytoplasmic mRNA processing body

FB:FBrf0200920
PMID:17403906[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0003725

double-stranded RNA binding

FB:FBrf0110978
PMID:10449356[2]

TAS: Traceable Author Statement

F

From FB

GO:0003725

double-stranded RNA binding

FB:FBrf0129923
PMID:10908586[3]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0003725

double-stranded RNA binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001159

F

From FB

GO:0003729

mRNA binding

FB:FBrf0151528
PMID:12142000[4]

NAS: Non-traceable Author Statement

F

From FB

GO:0003730

mRNA 3'-UTR binding

FB:FBrf0095575
PMID:9267024[5]

IDA: Inferred from Direct Assay

F

From FB

GO:0003730

mRNA 3'-UTR binding

FB:FBrf0192546
PMID:16835436[6]

IDA: Inferred from Direct Assay

F

From FB

GO:0005737

cytoplasm

FB:FBrf0106508
PMID:9888987[7]

IDA: Inferred from Direct Assay

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0132100
PMID:10908588[8]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005938

cell cortex

FB:FBrf0095575
PMID:9267024[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0006403

RNA localization

FB:FBrf0095575
PMID:9267024[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007017

microtubule-based process

FB:FBrf0132100
PMID:10908588[8]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0007315

pole plasm assembly

FB:FBrf0051552
PMID:2151612[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007315

pole plasm assembly

FB:FBrf0091199
PMID:8970731[10]

NAS: Non-traceable Author Statement

P

From FB

GO:0007316

pole plasm RNA localization

FB:FBrf0051552
PMID:2151612[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007317

regulation of pole plasm oskar mRNA localization

FB:FBrf0110978
PMID:10449356[2]

TAS: Traceable Author Statement

P

From FB

GO:0007317

regulation of pole plasm oskar mRNA localization

FB:FBrf0195060
PMID:16905128[11]

IGI: Inferred from Genetic Interaction

FB:FBgn0021776

P

From FB

GO:0007318

pole plasm protein localization

FB:FBrf0089980
PMID:8804312[12]

TAS: Traceable Author Statement

P

From FB

GO:0007318

pole plasm protein localization

FB:FBrf0195060
PMID:16905128[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007400

neuroblast fate determination

FB:FBrf0174511
PMID:15018932[13]

TAS: Traceable Author Statement

P

From FB

GO:0007616

long-term memory

FB:FBrf0158809
PMID:12593794[14]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007616

long-term memory

FB:FBrf0158825
PMID:12593811[15]

TAS: Traceable Author Statement

P

From FB

GO:0008017

microtubule binding

FB:FBrf0132100
PMID:10908588[8]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0008017

microtubule binding

FB:FBrf0151528
PMID:12142000[4]

NAS: Non-traceable Author Statement

F

From FB

GO:0008104

protein localization

FB:FBrf0141479
PMID:11784091[16]

TAS: Traceable Author Statement

P

From FB

GO:0008298

intracellular mRNA localization

FB:FBrf0123848

NAS: Non-traceable Author Statement

P

From FB

GO:0008298

intracellular mRNA localization

FB:FBrf0141479
PMID:11784091[16]

TAS: Traceable Author Statement

P

From FB

GO:0008298

intracellular mRNA localization

FB:FBrf0151528
PMID:12142000[4]

TAS: Traceable Author Statement

P

From FB

GO:0008595

anterior/posterior axis specification, embryo

FB:FBrf0195060
PMID:16905128[11]

IGI: Inferred from Genetic Interaction

FB:FBgn0021776

P

From FB

GO:0010606

positive regulation of cytoplasmic mRNA processing body assembly

FB:FBrf0200920
PMID:17403906[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0019094

pole plasm mRNA localization

FB:FBrf0145617
PMID:11845195[17]

TAS: Traceable Author Statement

P

From FB

GO:0045167

asymmetric protein localization involved in cell fate determination

FB:FBrf0174511
PMID:15018932[13]

TAS: Traceable Author Statement

P

From FB

GO:0045177

apical part of cell

FB:FBrf0106508
PMID:9888987[7]

IDA: Inferred from Direct Assay

C

From FB

GO:0045179

apical cortex

FB:FBrf0095575
PMID:9267024[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0045180

basal cortex

FB:FBrf0106508
PMID:9888987[7]

IDA: Inferred from Direct Assay

C

From FB

GO:0045180

basal cortex

FB:FBrf0152260
PMID:12447381[18]

NAS: Non-traceable Author Statement

C

From FB

GO:0045180

basal cortex

FB:FBrf0174511
PMID:15018932[13]

TAS: Traceable Author Statement

C

From FB

GO:0045450

bicoid mRNA localization

FB:FBrf0059245
PMID:7681599[19]

TAS: Traceable Author Statement

P

From FB

GO:0045450

bicoid mRNA localization

FB:FBrf0110978
PMID:10449356[2]

NAS: Non-traceable Author Statement

P

From FB

GO:0045450

bicoid mRNA localization

FB:FBrf0141280
PMID:11700288[20]

TAS: Traceable Author Statement

P

From FB

GO:0045451

pole plasm oskar mRNA localization

FB:FBrf0132358
PMID:11131516[21]

TAS: Traceable Author Statement

P

From FB

GO:0045451

pole plasm oskar mRNA localization

FB:FBrf0141280
PMID:11700288[20]

TAS: Traceable Author Statement

P

From FB

GO:0045451

pole plasm oskar mRNA localization

FB:FBrf0156083
PMID:12441250[22]

TAS: Traceable Author Statement

P

From FB

GO:0046011

regulation of oskar mRNA translation

FB:FBrf0110978
PMID:10449356[2]

TAS: Traceable Author Statement

P

From FB

GO:0046011

regulation of oskar mRNA translation

FB:FBrf0132358
PMID:11131516[21]

TAS: Traceable Author Statement

P

From FB

GO:0046012

positive regulation of oskar mRNA translation

FB:FBrf0156097
PMID:12446149[23]

NAS: Non-traceable Author Statement

P

From FB

GO:0046012

positive regulation of oskar mRNA translation

FB:FBrf0157336
PMID:12655640[24]

NAS: Non-traceable Author Statement

P

From FB

GO:0048477

oogenesis

FB:FBrf0107500
PMID:9988212[25]

TAS: Traceable Author Statement

P

From FB

GO:0055059

asymmetric neuroblast division

FB:FBrf0095575
PMID:9267024[5]

NAS: Non-traceable Author Statement

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Eulalio A et al. (2007) P-body formation is a consequence, not the cause, of RNA-mediated gene silencing. Mol Cell Biol 27: 3970-81 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 van Eeden F & St Johnston D (1999) The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis. Curr Opin Genet Dev 9: 396-404 PubMed GONUTS page
  3. Lasko P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J Cell Biol 150: F51-6 PubMed GONUTS page
  4. 4.0 4.1 4.2 Holloway DM et al. (2002) Sharp borders from fuzzy gradients. Trends Genet 18: 385-7 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 Li P et al. (1997) Inscuteable and Staufen mediate asymmetric localization and segregation of prospero RNA during Drosophila neuroblast cell divisions. Cell 90: 437-47 PubMed GONUTS page
  6. Jenny A et al. (2006) A translation-independent role of oskar RNA in early Drosophila oogenesis. Development 133: 2827-33 PubMed GONUTS page
  7. 7.0 7.1 7.2 Fuerstenberg S et al. (1998) Identification of Miranda protein domains regulating asymmetric cortical localization, cargo binding, and cortical release. Mol Cell Neurosci 12: 325-39 PubMed GONUTS page
  8. 8.0 8.1 8.2 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
  9. 9.0 9.1 Raff JW et al. (1990) Two distinct mechanisms localise cyclin B transcripts in syncytial Drosophila embryos. Development 110: 1249-61 PubMed GONUTS page
  10. Williamson A & Lehmann R (1996) Germ cell development in Drosophila. Annu Rev Cell Dev Biol 12: 365-91 PubMed GONUTS page
  11. 11.0 11.1 11.2 Irion U et al. (2006) Miranda couples oskar mRNA/Staufen complexes to the bicoid mRNA localization pathway. Dev Biol 297: 522-33 PubMed GONUTS page
  12. Breitwieser W et al. (1996) Oskar protein interaction with Vasa represents an essential step in polar granule assembly. Genes Dev 10: 2179-88 PubMed GONUTS page
  13. 13.0 13.1 13.2 Bardin AJ et al. (2004) Asymmetric localization and function of cell-fate determinants: a fly's view. Curr Opin Neurobiol 14: 6-14 PubMed GONUTS page
  14. Dubnau J et al. (2003) The staufen/pumilio pathway is involved in Drosophila long-term memory. Curr Biol 13: 286-96 PubMed GONUTS page
  15. Greenspan RJ (2003) RNA and memory: from feeding to localization. Curr Biol 13: R126-7 PubMed GONUTS page
  16. 16.0 16.1 Sardet C et al. (2002) Structure and function of the egg cortex from oogenesis through fertilization. Dev Biol 241: 1-23 PubMed GONUTS page
  17. Patel NH & Lall S (2002) Precision patterning. Nature 415: 748-9 PubMed GONUTS page
  18. Cayouette M & Raff M (2002) Asymmetric segregation of Numb: a mechanism for neural specification from Drosophila to mammals. Nat Neurosci 5: 1265-9 PubMed GONUTS page
  19. Ding D et al. (1993) Different genetic requirements for anterior RNA localization revealed by the distribution of Adducin-like transcripts during Drosophila oogenesis. Proc Natl Acad Sci U S A 90: 2512-6 PubMed GONUTS page
  20. 20.0 20.1 Johnstone O & Lasko P (2001) Translational regulation and RNA localization in Drosophila oocytes and embryos. Annu Rev Genet 35: 365-406 PubMed GONUTS page
  21. 21.0 21.1 Mahowald AP (2001) Assembly of the Drosophila germ plasm. Int Rev Cytol 203: 187-213 PubMed GONUTS page
  22. Farina KL & Singer RH (2002) The nuclear connection in RNA transport and localization. Trends Cell Biol 12: 466-72 PubMed GONUTS page
  23. Tekotte H & Davis I (2002) Intracellular mRNA localization: motors move messages. Trends Genet 18: 636-42 PubMed GONUTS page
  24. Leatherman JL & Jongens TA (2003) Transcriptional silencing and translational control: key features of early germline development. Bioessays 25: 326-35 PubMed GONUTS page
  25. Wylie C (1999) Germ cells. Cell 96: 165-74 PubMed GONUTS page
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