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FB:srp
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | srp ( synonyms: A-box-binding factor, A7.1, ABF, Abf, CG3992, DmGATAb, GATA, GATAb, SERPENT, SRP, Serpent, Srp, abf, dGATAb, l(3)01549, l(3)89B2, l(3)neo45, serpentD, spt, srpD ) | |
| Protein Name(s) | serpent, | |
| External Links | ||
| FB | FBgn0003507 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001077 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
FB:FBrf0065324 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0001700 |
embryonic development via the syncytial blastoderm |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0001706 |
endoderm formation |
FB:FBrf0147042 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0001709 |
cell fate determination |
FB:FBrf0111439 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0001710 |
mesodermal cell fate commitment |
FB:FBrf0134564 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0065324 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0151958 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0158758 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0065324 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:4170 |
F |
From FB |
||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0065324 |
ISS: Inferred from Sequence or Structural Similarity |
HGNC:4171 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0151958 |
IPI: Inferred from Physical Interaction |
FB:FBgn0003963 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0091301 |
ISS: Inferred from Sequence or Structural Similarity |
WP:CE21285 |
P |
From FB |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0141163 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006911 |
phagocytosis, engulfment |
FB:FBrf0191376 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006952 |
defense response |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007390 |
germ-band shortening |
FB:FBrf0087131 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007390 |
germ-band shortening |
FB:FBrf0090577 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007390 |
germ-band shortening |
FB:FBrf0111406 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007390 |
germ-band shortening |
FB:FBrf0151280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007391 |
dorsal closure |
FB:FBrf0151280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007435 |
salivary gland morphogenesis |
FB:FBrf0190174 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007492 |
endoderm development |
FB:FBrf0111439 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007494 |
midgut development |
FB:FBrf0111439 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007494 |
midgut development |
FB:FBrf0147042 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007503 |
fat body development |
FB:FBrf0065324 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0007503 |
fat body development |
FB:FBrf0091301 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0007503 |
fat body development |
FB:FBrf0102832 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007516 |
hemocyte development |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007516 |
hemocyte development |
FB:FBrf0144845 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007516 |
hemocyte development |
FB:FBrf0184064 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007516 |
hemocyte development |
FB:FBrf0205363 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008258 |
head involution |
FB:FBrf0087131 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0008354 |
germ cell migration |
FB:FBrf0100771 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008354 |
germ cell migration |
FB:FBrf0107500 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009987 |
cellular process |
FB:FBrf0175143 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030097 |
hemopoiesis |
FB:FBrf0091301 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0030097 |
hemopoiesis |
FB:FBrf0091301 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030097 |
hemopoiesis |
FB:FBrf0131266 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030097 |
hemopoiesis |
FB:FBrf0141068 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030097 |
hemopoiesis |
FB:FBrf0158758 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035050 |
embryonic heart tube development |
FB:FBrf0187463 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035162 |
embryonic hemopoiesis |
FB:FBrf0127186 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035162 |
embryonic hemopoiesis |
FB:FBrf0151958 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035162 |
embryonic hemopoiesis |
FB:FBrf0167434 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035162 |
embryonic hemopoiesis |
FB:FBrf0167476 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035167 |
larval lymph gland hemopoiesis |
FB:FBrf0167434 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035167 |
larval lymph gland hemopoiesis |
FB:FBrf0167476 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035167 |
larval lymph gland hemopoiesis |
FB:FBrf0212074 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042688 |
crystal cell differentiation |
FB:FBrf0167476 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0042690 |
negative regulation of crystal cell differentiation |
FB:FBrf0158758 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0043565 |
sequence-specific DNA binding |
FB:FBrf0195108 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0045165 |
cell fate commitment |
FB:FBrf0147042 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045165 |
cell fate commitment |
FB:FBrf0167476 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
FB:FBrf0065324 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0046665 |
amnioserosa maintenance |
FB:FBrf0087131 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046665 |
amnioserosa maintenance |
FB:FBrf0151280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048542 |
lymph gland development |
FB:FBrf0180561 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048542 |
lymph gland development |
FB:FBrf0212074 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Abel T et al. (1993) A Drosophila GATA family member that binds to Adh regulatory sequences is expressed in the developing fat body. Development 119: 623-33 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Stainier DY (2002) A glimpse into the molecular entrails of endoderm formation. Genes Dev 16: 893-907 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Murakami R et al. (1999) Developmental genetics of the Drosophila gut: specification of primordia, subdivision and overt-differentiation. Cell Mol Biol (Noisy-le-grand) 45: 661-76 PubMed GONUTS page
- ↑ Hayes SA et al. (2001) serpent, a GATA-like transcription factor gene, induces fat-cell development in Drosophila melanogaster. Development 128: 1193-200 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Waltzer L et al. (2002) Two isoforms of Serpent containing either one or two GATA zinc fingers have different roles in Drosophila haematopoiesis. EMBO J 21: 5477-86 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Evans CJ & Banerjee U (2003) Transcriptional regulation of hematopoiesis in Drosophila. Blood Cells Mol Dis 30: 223-8 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Rehorn KP et al. (1996) A molecular aspect of hematopoiesis and endoderm development common to vertebrates and Drosophila. Development 122: 4023-31 PubMed GONUTS page
- ↑ Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Frank LH & Rushlow C (1996) A group of genes required for maintenance of the amnioserosa tissue in Drosophila. Development 122: 1343-52 PubMed GONUTS page
- ↑ Goldman-Levi R et al. (1996) Cellular pathways acting along the germband and in the amnioserosa may participate in germband retraction of the Drosophila melanogaster embryo. Int J Dev Biol 40: 1043-51 PubMed GONUTS page
- ↑ Lamka ML & Lipshitz HD (1999) Role of the amnioserosa in germ band retraction of the Drosophila melanogaster embryo. Dev Biol 214: 102-12 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
- ↑ Vining MS et al. (2005) Organ positioning in Drosophila requires complex tissue-tissue interactions. Dev Biol 287: 19-34 PubMed GONUTS page
- ↑ Howard K (1998) Organogenesis: Drosophila goes gonadal. Curr Biol 8: R415-7 PubMed GONUTS page
- ↑ Fossett N & Schulz RA (2001) Functional conservation of hematopoietic factors in Drosophila and vertebrates. Differentiation 69: 83-90 PubMed GONUTS page
- ↑ Stramer B et al. (2005) Live imaging of wound inflammation in Drosophila embryos reveals key roles for small GTPases during in vivo cell migration. J Cell Biol 168: 567-73 PubMed GONUTS page
- ↑ Stramer B et al. (2008) Gene induction following wounding of wild-type versus macrophage-deficient Drosophila embryos. EMBO Rep 9: 465-71 PubMed GONUTS page
- ↑ Moore LA et al. (1998) Identification of genes controlling germ cell migration and embryonic gonad formation in Drosophila. Development 125: 667-78 PubMed GONUTS page
- ↑ Wylie C (1999) Germ cells. Cell 96: 165-74 PubMed GONUTS page
- ↑ Boutros M et al. (2004) Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303: 832-5 PubMed GONUTS page
- ↑ Canon J & Banerjee U (2000) Runt and Lozenge function in Drosophila development. Semin Cell Dev Biol 11: 327-36 PubMed GONUTS page
- ↑ Kimbrell DA & Beutler B (2001) The evolution and genetics of innate immunity. Nat Rev Genet 2: 256-67 PubMed GONUTS page
- ↑ Han Z & Olson EN (2005) Hand is a direct target of Tinman and GATA factors during Drosophila cardiogenesis and hematopoiesis. Development 132: 3525-36 PubMed GONUTS page
- ↑ Lebestky T et al. (2000) Specification of Drosophila hematopoietic lineage by conserved transcription factors. Science 288: 146-9 PubMed GONUTS page
- ↑ 25.0 25.1 Meister M (2004) Blood cells of Drosophila: cell lineages and role in host defence. Curr Opin Immunol 16: 10-5 PubMed GONUTS page
- ↑ 26.0 26.1 26.2 26.3 Evans CJ et al. (2003) Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev Cell 5: 673-90 PubMed GONUTS page
- ↑ 27.0 27.1 Tokusumi Y et al. (2010) Serpent, suppressor of hairless and U-shaped are crucial regulators of hedgehog niche expression and prohemocyte maintenance during Drosophila larval hematopoiesis. Development 137: 3561-8 PubMed GONUTS page
- ↑ Muratoglu S et al. (2006) Regulation of Drosophila friend of GATA gene, u-shaped, during hematopoiesis: a direct role for serpent and lozenge. Dev Biol 296: 561-79 PubMed GONUTS page
- ↑ Mandal L et al. (2004) Evidence for a fruit fly hemangioblast and similarities between lymph-gland hematopoiesis in fruit fly and mammal aorta-gonadal-mesonephros mesoderm. Nat Genet 36: 1019-23 PubMed GONUTS page
