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FB:spn-E
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | spn-E ( synonyms: CG3158, HOMELESS, Homeless, SPN-E, Spindle E, Spindle-E, Spindle-E (homeless), SpindleE, Spn-E, female sterile(3)homeless, fs(1)hls, fs(3)hls, hes, hls, homeless, homeless/spindle-E, spin-E, spindle-E, spn E, spn-E/hls, spnE ) | |
| Protein Name(s) | spindle E, | |
| External Links | ||
| FB | FBgn0003483 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001556 |
oocyte maturation |
FB:FBrf0151326 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003676 |
nucleic acid binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0003724 |
RNA helicase activity |
FB:FBrf0110978 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0004004 |
ATP-dependent RNA helicase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004386 |
helicase activity |
FB:FBrf0129923 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0189910 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0107896 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0189910 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006342 |
chromatin silencing |
FB:FBrf0168038 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006403 |
RNA localization |
FB:FBrf0107500 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007076 |
mitotic chromosome condensation |
FB:FBrf0212718 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007294 |
germarium-derived oocyte fate determination |
FB:FBrf0100046 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0002899 |
P |
From FB |
||
| GO:0007315 |
pole plasm assembly |
FB:FBrf0091199 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007317 |
regulation of pole plasm oskar mRNA localization |
FB:FBrf0174441 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008186 |
RNA-dependent ATPase activity |
FB:FBrf0107500 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0008298 |
intracellular mRNA localization |
FB:FBrf0100046 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008298 |
intracellular mRNA localization |
FB:FBrf0103246 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009949 |
polarity specification of anterior/posterior axis |
FB:FBrf0100046 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0009951 |
polarity specification of dorsal/ventral axis |
FB:FBrf0100046 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0009994 |
oocyte differentiation |
FB:FBrf0132360 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0016246 |
RNA interference |
FB:FBrf0179041 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016246 |
RNA interference |
FB:FBrf0179908 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030423 |
targeting of mRNA for destruction involved in RNA interference |
FB:FBrf0151326 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030717 |
karyosome formation |
FB:FBrf0100046 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030720 |
oocyte localization involved in germarium-derived egg chamber formation |
FB:FBrf0100046 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043186 |
P granule |
FB:FBrf0211166 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045451 |
pole plasm oskar mRNA localization |
FB:FBrf0160777 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046843 |
dorsal appendage formation |
FB:FBrf0192439 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0100046 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000810 |
P |
From FB |
||
| GO:0048477 |
oogenesis |
FB:FBrf0107500 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0110978 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0060213 |
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening |
FB:FBrf0212183 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Kennerdell JR et al. (2002) RNAi is activated during Drosophila oocyte maturation in a manner dependent on aubergine and spindle-E. Genes Dev 16: 1884-9 PubMed GONUTS page
- ↑ 2.0 2.1 van Eeden F & St Johnston D (1999) The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis. Curr Opin Genet Dev 9: 396-404 PubMed GONUTS page
- ↑ Lasko P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J Cell Biol 150: F51-6 PubMed GONUTS page
- ↑ 4.0 4.1 Grimaud C et al. (2006) RNAi components are required for nuclear clustering of Polycomb group response elements. Cell 124: 957-71 PubMed GONUTS page
- ↑ Morris J & Lehmann R (1999) Drosophila oogenesis: versatile spn doctors. Curr Biol 9: R55-8 PubMed GONUTS page
- ↑ Pal-Bhadra M et al. (2004) Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery. Science 303: 669-72 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Wylie C (1999) Germ cells. Cell 96: 165-74 PubMed GONUTS page
- ↑ Pek JW & Kai T (2011) A role for vasa in regulating mitotic chromosome condensation in Drosophila. Curr Biol 21: 39-44 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 9.4 9.5 9.6 González-Reyes A et al. (1997) Oocyte determination and the origin of polarity in Drosophila: the role of the spindle genes. Development 124: 4927-37 PubMed GONUTS page
- ↑ Williamson A & Lehmann R (1996) Germ cell development in Drosophila. Annu Rev Cell Dev Biol 12: 365-91 PubMed GONUTS page
- ↑ Cook HA et al. (2004) The Drosophila SDE3 homolog armitage is required for oskar mRNA silencing and embryonic axis specification. Cell 116: 817-29 PubMed GONUTS page
- ↑ Cooperstock RL & Lipshitz HD (1997) Control of mRNA stability and translation during Drosophila development. Semin Cell Dev Biol 8: 541-9 PubMed GONUTS page
- ↑ Deng W & Lin H (2001) Asymmetric germ cell division and oocyte determination during Drosophila oogenesis. Int Rev Cytol 203: 93-138 PubMed GONUTS page
- ↑ Lavorgna G et al. (2004) In search of antisense. Trends Biochem Sci 29: 88-94 PubMed GONUTS page
- ↑ Murchison EP & Hannon GJ (2004) miRNAs on the move: miRNA biogenesis and the RNAi machinery. Curr Opin Cell Biol 16: 223-9 PubMed GONUTS page
- ↑ Patil VS & Kai T (2010) Repression of retroelements in Drosophila germline via piRNA pathway by the Tudor domain protein Tejas. Curr Biol 20: 724-30 PubMed GONUTS page
- ↑ Martin SG et al. (2003) The identification of novel genes required for Drosophila anteroposterior axis formation in a germline clone screen using GFP-Staufen. Development 130: 4201-15 PubMed GONUTS page
- ↑ Klattenhoff C et al. (2007) Drosophila rasiRNA pathway mutations disrupt embryonic axis specification through activation of an ATR/Chk2 DNA damage response. Dev Cell 12: 45-55 PubMed GONUTS page
- ↑ Rouget C et al. (2010) Maternal mRNA deadenylation and decay by the piRNA pathway in the early Drosophila embryo. Nature 467: 1128-32 PubMed GONUTS page
