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FB:spi
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | spi ( synonyms: CG10334, CT29014, EP(2)2378, Spi, Spitz, anon-WO0118547.158, l(2)01068, l(2)37Fa, l(2)s3547, s-spi, sSpi ) | |
| Protein Name(s) | spitz, | |
| External Links | ||
| FB | FBgn0005672 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000086 |
G2/M transition of mitotic cell cycle |
FB:FBrf0141762 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0003015 |
heart process |
FB:FBrf0210954 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005154 |
epidermal growth factor receptor binding |
FB:FBrf0102528 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005154 |
epidermal growth factor receptor binding |
FB:FBrf0110978 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005154 |
epidermal growth factor receptor binding |
FB:FBrf0158927 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005576 |
extracellular region |
FB:FBrf0102528 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005576 |
extracellular region |
FB:FBrf0158927 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005783 |
endoplasmic reticulum |
FB:FBrf0139606 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005783 |
endoplasmic reticulum |
FB:FBrf0158927 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005783 |
endoplasmic reticulum |
FB:FBrf0180127 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005794 |
Golgi apparatus |
FB:FBrf0139606 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003310 |
C |
From FB |
||
| GO:0005886 |
plasma membrane |
FB:FBrf0124194 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0006916 |
anti-apoptosis |
FB:FBrf0149190 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007173 |
epidermal growth factor receptor signaling pathway |
FB:FBrf0102528 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007173 |
epidermal growth factor receptor signaling pathway |
FB:FBrf0136839 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007173 |
epidermal growth factor receptor signaling pathway |
FB:FBrf0141518 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007173 |
epidermal growth factor receptor signaling pathway |
FB:FBrf0158927 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007298 |
border follicle cell migration |
FB:FBrf0193922 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007421 |
stomatogastric nervous system development |
FB:FBrf0135746 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007422 |
peripheral nervous system development |
FB:FBrf0162204 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007424 |
open tracheal system development |
FB:FBrf0167264 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007432 |
salivary gland boundary specification |
FB:FBrf0139594 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007438 |
oenocyte development |
FB:FBrf0148967 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000014 |
P |
From FB |
||
| GO:0007438 |
oenocyte development |
FB:FBrf0148967 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007476 |
imaginal disc-derived wing morphogenesis |
FB:FBrf0193945 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008284 |
positive regulation of cell proliferation |
FB:FBrf0206542 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008284 |
positive regulation of cell proliferation |
FB:FBrf0212840 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008317 |
gurken receptor binding |
FB:FBrf0124194 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0016021 |
integral to membrane |
FB:FBrf0144824 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0016021 |
integral to membrane |
FB:FBrf0158927 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0016330 |
second mitotic wave involved in compound eye morphogenesis |
FB:FBrf0141762 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0022008 |
neurogenesis |
FB:FBrf0214431 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035225 |
determination of genital disc primordium |
FB:FBrf0187379 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0035277 |
spiracle morphogenesis, open tracheal system |
FB:FBrf0187474 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043066 |
negative regulation of apoptotic process |
FB:FBrf0193620 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045470 |
R8 cell-mediated photoreceptor organization |
FB:FBrf0144824 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045742 |
positive regulation of epidermal growth factor receptor signaling pathway |
FB:FBrf0110978 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0046673 |
negative regulation of compound eye retinal cell programmed cell death |
FB:FBrf0156100 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0046845 |
branched duct epithelial cell fate determination, open tracheal system |
FB:FBrf0125237 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048149 |
behavioral response to ethanol |
FB:FBrf0208186 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048865 |
stem cell fate commitment |
FB:FBrf0210887 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0061331 |
epithelial cell proliferation involved in Malpighian tubule morphogenesis |
FB:FBrf0102951 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Baker NE (2001) Cell proliferation, survival, and death in the Drosophila eye. Semin Cell Dev Biol 12: 499-507 PubMed GONUTS page
- ↑ Yu L et al. (2010) Affecting Rhomboid-3 function causes a dilated heart in adult Drosophila. PLoS Genet 6: e1000969 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Bier E (1998) Localized activation of RTK/MAPK pathways during Drosophila development. Bioessays 20: 189-94 PubMed GONUTS page
- ↑ 4.0 4.1 van Eeden F & St Johnston D (1999) The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis. Curr Opin Genet Dev 9: 396-404 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 Shilo BZ (2003) Signaling by the Drosophila epidermal growth factor receptor pathway during development. Exp Cell Res 284: 140-9 PubMed GONUTS page
- ↑ 6.0 6.1 Lee JR et al. (2001) Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila. Cell 107: 161-71 PubMed GONUTS page
- ↑ Schlesinger A et al. (2004) Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila. Dev Cell 7: 535-45 PubMed GONUTS page
- ↑ Hidalgo A (2002) Interactive nervous system development: control of cell survival in Drosophila. Trends Neurosci 25: 365-70 PubMed GONUTS page
- ↑ Sanson B (2001) Generating patterns from fields of cells. Examples from Drosophila segmentation. EMBO Rep 2: 1083-8 PubMed GONUTS page
- ↑ McDonald JA et al. (2006) Multiple EGFR ligands participate in guiding migrating border cells. Dev Biol 296: 94-103 PubMed GONUTS page
- ↑ González-Gaitán M & Jäckle H (2000) Tip cell-derived RTK signaling initiates cell movements in the Drosophila stomatogastric nervous system anlage. EMBO Rep 1: 366-71 PubMed GONUTS page
- ↑ Sepp KJ & Auld VJ (2003) Reciprocal interactions between neurons and glia are required for Drosophila peripheral nervous system development. J Neurosci 23: 8221-30 PubMed GONUTS page
- ↑ Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
- ↑ Bradley PL et al. (2001) Organ formation in Drosophila: specification and morphogenesis of the salivary gland. Bioessays 23: 901-11 PubMed GONUTS page
- ↑ 15.0 15.1 Brodu V et al. (2002) abdominal A specifies one cell type in Drosophila by regulating one principal target gene. Development 129: 2957-63 PubMed GONUTS page
- ↑ Dworkin I & Gibson G (2006) Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster. Genetics 173: 1417-31 PubMed GONUTS page
- ↑ Jiang H & Edgar BA (2009) EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors. Development 136: 483-93 PubMed GONUTS page
- ↑ Buchon N et al. (2010) Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol 8: 152 PubMed GONUTS page
- ↑ 19.0 19.1 Frankfort BJ & Mardon G (2002) R8 development in the Drosophila eye: a paradigm for neural selection and differentiation. Development 129: 1295-306 PubMed GONUTS page
- ↑ Chen EH et al. (2005) Allocation and specification of the genital disc precursor cells in Drosophila. Dev Biol 281: 270-85 PubMed GONUTS page
- ↑ Merabet S et al. (2005) Hox-controlled reorganisation of intrasegmental patterning cues underlies Drosophila posterior spiracle organogenesis. Development 132: 3093-102 PubMed GONUTS page
- ↑ Parker J (2006) Control of compartment size by an EGF ligand from neighboring cells. Curr Biol 16: 2058-65 PubMed GONUTS page
- ↑ Brachmann CB & Cagan RL (2003) Patterning the fly eye: the role of apoptosis. Trends Genet 19: 91-6 PubMed GONUTS page
- ↑ Zelzer E & Shilo BZ (2000) Cell fate choices in Drosophila tracheal morphogenesis. Bioessays 22: 219-26 PubMed GONUTS page
- ↑ Corl AB et al. (2009) Happyhour, a Ste20 family kinase, implicates EGFR signaling in ethanol-induced behaviors. Cell 137: 949-60 PubMed GONUTS page
- ↑ Figeac N et al. (2010) Drosophila adult muscle precursors form a network of interconnected cells and are specified by the rhomboid-triggered EGF pathway. Development 137: 1965-73 PubMed GONUTS page
- ↑ Kerber B et al. (1998) Seven-up, the Drosophila homolog of the COUP-TF orphan receptors, controls cell proliferation in the insect kidney. Genes Dev 12: 1781-6 PubMed GONUTS page
