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FB:spen

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) spen ( synonyms: 136/24, BcDNA:GM01870, CG18497, E(E2F)2A, E(Raf)2A, E(Sev-CycE)2A, EK2-9, EY2-7, En(yan(ACT))2-7, Split ends, Splitends, l(2)03350, l(2)k06805, l(2)k07612, l(2)k08102, poc, polycephalon, rhinoceros, rno, spe, split-ends, yip1, yippee interacting protein 1 )
Protein Name(s) split ends,
External Links
FB FBgn0016977

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR012677

F

From FB

GO:0003676

nucleic acid binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000504

F

From FB

GO:0005634

nucleus

FB:FBrf0112078
PMID:10556062[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0125611

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0126772
PMID:10704397[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0160742
PMID:12783785[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0112078
PMID:10556062[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007173

epidermal growth factor receptor signaling pathway

FB:FBrf0129761
PMID:10959845[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007379

segment specification

FB:FBrf0112078
PMID:10556062[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007400

neuroblast fate determination

FB:FBrf0126772
PMID:10704397[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007403

glial cell fate determination

FB:FBrf0129761
PMID:10959845[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007411

axon guidance

FB:FBrf0126772
PMID:10704397[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007411

axon guidance

FB:FBrf0129761
PMID:10959845[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0183733
PMID:15596016[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008347

glial cell migration

FB:FBrf0129761
PMID:10959845[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008586

imaginal disc-derived wing vein morphogenesis

FB:FBrf0183733
PMID:15596016[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0160742
PMID:12783785[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035321

maintenance of imaginal disc-derived wing hair orientation

FB:FBrf0183733
PMID:15596016[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048106

establishment of thoracic bristle planar orientation

FB:FBrf0183733
PMID:15596016[5]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Wiellette EL et al. (1999) spen encodes an RNP motif protein that interacts with Hox pathways to repress the development of head-like sclerites in the Drosophila trunk. Development 126: 5373-85 PubMed GONUTS page
  2. 2.0 2.1 2.2 Kuang B et al. (2000) split ends encodes large nuclear proteins that regulate neuronal cell fate and axon extension in the Drosophila embryo. Development 127: 1517-29 PubMed GONUTS page
  3. 3.0 3.1 Lin HV et al. (2003) Splits ends is a tissue/promoter specific regulator of Wingless signaling. Development 130: 3125-35 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Chen F & Rebay I (2000) split ends, a new component of the Drosophila EGF receptor pathway, regulates development of midline glial cells. Curr Biol 10: 943-6 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Mace K & Tugores A (2004) The product of the split ends gene is required for the maintenance of positional information during Drosophila development. BMC Dev Biol 4: 15 PubMed GONUTS page
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