![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:spdo
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | spdo ( synonyms: 0970/02, BcDNA:RE23355, CG31020, Sanpodo, Spdo, tropomodulin ) | |
| Protein Name(s) | sanpodo, | |
| External Links | ||
| FB | FBgn0260440 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003007 |
heart morphogenesis |
FB:FBrf0195313 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005112 |
Notch binding |
FB:FBrf0162056 |
IPI: Inferred from Physical Interaction |
FB:FBgn0004647 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0162056 |
IPI: Inferred from Physical Interaction |
FB:FBgn0002973 |
F |
From FB |
||
| GO:0005737 |
cytoplasm |
FB:FBrf0162056 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005769 |
early endosome |
FB:FBrf0187517 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005770 |
late endosome |
FB:FBrf0187517 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0162056 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0187517 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0188062 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007219 |
Notch signaling pathway |
FB:FBrf0162056 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004647 |
P |
From FB |
||
| GO:0007219 |
Notch signaling pathway |
FB:FBrf0162056 |
IPI: Inferred from Physical Interaction |
FB:FBgn0004647 |
P |
From FB |
||
| GO:0007422 |
peripheral nervous system development |
FB:FBrf0083410 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007422 |
peripheral nervous system development |
FB:FBrf0131381 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007423 |
sensory organ development |
FB:FBrf0188062 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008356 |
asymmetric cell division |
FB:FBrf0162056 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008356 |
asymmetric cell division |
FB:FBrf0209326 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0016021 |
integral to membrane |
FB:FBrf0162056 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0030863 |
cortical cytoskeleton |
FB:FBrf0188062 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045035 |
sensory organ precursor cell division |
FB:FBrf0187517 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045035 |
sensory organ precursor cell division |
FB:FBrf0209326 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045746 |
negative regulation of Notch signaling pathway |
FB:FBrf0209326 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
colocalizes_with |
GO:0005886 |
plasma membrane |
FB:FBrf0190204 |
IDA: Inferred from Direct Assay |
C |
From FB |
||
|
colocalizes_with |
GO:0031410 |
cytoplasmic vesicle |
FB:FBrf0190204 |
IDA: Inferred from Direct Assay |
C |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Albrecht S et al. (2006) The ADAM metalloprotease Kuzbanian is crucial for proper heart formation in Drosophila melanogaster. Mech Dev 123: 372-87 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 O'Connor-Giles KM & Skeath JB (2003) Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila. Dev Cell 5: 231-43 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Hutterer A & Knoblich JA (2005) Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs. EMBO Rep 6: 836-42 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Roegiers F et al. (2005) Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs. Mol Biol Cell 16: 3480-7 PubMed GONUTS page
- ↑ Salzberg A et al. (1994) Mutations affecting the pattern of the PNS in Drosophila reveal novel aspects of neuronal development. Neuron 13: 269-87 PubMed GONUTS page
- ↑ Prokopenko SN et al. (2000) Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins. Genetics 156: 1691-715 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Babaoglan AB et al. (2009) Sanpodo: a context-dependent activator and inhibitor of Notch signaling during asymmetric divisions. Development 136: 4089-98 PubMed GONUTS page
- ↑ 8.0 8.1 Jafar-Nejad H et al. (2005) Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors. Dev Cell 9: 351-63 PubMed GONUTS page