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FB:spas
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | spas ( synonyms: CG5977, D-spastin, Dm-Spastin, Dspastin, Spas, Spastin, spasin ) | |
| Protein Name(s) | spastin, | |
| External Links | ||
| FB | FBgn0039141 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000070 |
mitotic sister chromatid segregation |
FB:FBrf0200649 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000091 |
mitotic anaphase A |
FB:FBrf0200649 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000226 |
microtubule cytoskeleton organization |
FB:FBrf0180480 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000226 |
microtubule cytoskeleton organization |
FB:FBrf0210787 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005694 |
chromosome |
FB:FBrf0200649 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0179488 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0187332 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005813 |
centrosome |
FB:FBrf0200649 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007626 |
locomotory behavior |
FB:FBrf0180480 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008568 |
microtubule-severing ATPase activity |
FB:FBrf0200649 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0016887 |
ATPase activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
SGD:S0004389 |
F |
From FB |
||
| GO:0016887 |
ATPase activity |
FB:FBrf0187332 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0019226 |
transmission of nerve impulse |
FB:FBrf0182537 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0031117 |
positive regulation of microtubule depolymerization |
FB:FBrf0179488 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031117 |
positive regulation of microtubule depolymerization |
FB:FBrf0187332 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0035099 |
hemocyte migration |
FB:FBrf0210787 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0036078 |
minus-end specific microtubule depolymerization |
FB:FBrf0200649 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043195 |
terminal button |
FB:FBrf0179488 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0048167 |
regulation of synaptic plasticity |
FB:FBrf0182537 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0051013 |
microtubule severing |
FB:FBrf0200649 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Zhang D et al. (2007) Three microtubule severing enzymes contribute to the "Pacman-flux" machinery that moves chromosomes. J Cell Biol 177: 231-42 PubMed GONUTS page
- ↑ 2.0 2.1 Sherwood NT et al. (2004) Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function. PLoS Biol 2: e429 PubMed GONUTS page
- ↑ 3.0 3.1 Stramer B et al. (2010) Clasp-mediated microtubule bundling regulates persistent motility and contact repulsion in Drosophila macrophages in vivo. J Cell Biol 189: 681-9 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Trotta N et al. (2004) The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function. Curr Biol 14: 1135-47 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Roll-Mecak A & Vale RD (2005) The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules. Curr Biol 15: 650-5 PubMed GONUTS page
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