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FB:sna

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) sna ( synonyms: BG:DS01845.1, CG3956, SNA, Sco, Scutoid, Sna, Snail, br28, br29, l(2)35Db, l(2)br28, l(2)br29, l(3)br28, l35Db, sn )
Protein Name(s) snail,
External Links
FB FBgn0003448

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000122

negative regulation of transcription from RNA polymerase II promoter

FB:FBrf0110176
PMID:10369659[1]

TAS: Traceable Author Statement

P

From FB

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

FB:FBrf0111461
PMID:10490660[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

FB:FBrf0141797
PMID:11691830[3]

TAS: Traceable Author Statement

P

From FB

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

FB:FBrf0204267
PMID:18309295[4]

IDA: Inferred from Direct Assay

P

From FB

GO:0000977

RNA polymerase II regulatory region sequence-specific DNA binding

FB:FBrf0111461
PMID:10490660[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0001710

mesodermal cell fate commitment

FB:FBrf0075064

TAS: Traceable Author Statement

P

From FB

GO:0003677

DNA binding

FB:FBrf0123443

NAS: Non-traceable Author Statement

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0105495

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0057526
PMID:1533042[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0057526
PMID:1533042[5]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005634

nucleus

FB:FBrf0105495

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0112152
PMID:10471707[6]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005634

nucleus

FB:FBrf0123443

NAS: Non-traceable Author Statement

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0105495

NAS: Non-traceable Author Statement

P

From FB

GO:0007369

gastrulation

FB:FBrf0110176
PMID:10369659[1]

NAS: Non-traceable Author Statement

P

From FB

GO:0007370

ventral furrow formation

FB:FBrf0075064

TAS: Traceable Author Statement

P

From FB

GO:0007375

anterior midgut invagination

FB:FBrf0075064

NAS: Non-traceable Author Statement

P

From FB

GO:0007417

central nervous system development

FB:FBrf0111784
PMID:10562554[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007443

Malpighian tubule morphogenesis

FB:FBrf0111391
PMID:10502111[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007450

dorsal/ventral pattern formation, imaginal disc

FB:FBrf0123443

NAS: Non-traceable Author Statement

P

From FB

GO:0007498

mesoderm development

FB:FBrf0130167
PMID:11128983[9]

TAS: Traceable Author Statement

P

From FB

GO:0007498

mesoderm development

FB:FBrf0148941
PMID:12027434[10]

NAS: Non-traceable Author Statement

P

From FB

GO:0007498

mesoderm development

FB:FBrf0151249
PMID:12027431[11]

TAS: Traceable Author Statement

P

From FB

GO:0007499

ectoderm and mesoderm interaction

FB:FBrf0147042
PMID:11959838[12]

NAS: Non-traceable Author Statement

P

From FB

GO:0007500

mesodermal cell fate determination

FB:FBrf0108595
PMID:10218153[13]

TAS: Traceable Author Statement

P

From FB

GO:0007501

mesodermal cell fate specification

FB:FBrf0141281
PMID:11700289[14]

TAS: Traceable Author Statement

P

From FB

GO:0007517

muscle organ development

FB:FBrf0190556
PMID:16547170[15]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR007087
InterPro:IPR015880

F

From FB

GO:0009950

dorsal/ventral axis specification

FB:FBrf0141281
PMID:11700289[14]

NAS: Non-traceable Author Statement

P

From FB

GO:0010004

gastrulation involving germ band extension

FB:FBrf0174529
PMID:15110709[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0010004

gastrulation involving germ band extension

FB:FBrf0179905
PMID:15380237[17]

TAS: Traceable Author Statement

P

From FB

GO:0010629

negative regulation of gene expression

FB:FBrf0193889
PMID:16780828[18]

IDA: Inferred from Direct Assay

P

From FB

GO:0031065

positive regulation of histone deacetylation

FB:FBrf0204267
PMID:18309295[4]

IDA: Inferred from Direct Assay

P

From FB

GO:0043565

sequence-specific DNA binding

FB:FBrf0057526
PMID:1533042[5]

IDA: Inferred from Direct Assay

F

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0111784
PMID:10562554[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048749

compound eye development

FB:FBrf0193889
PMID:16780828[18]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048813

dendrite morphogenesis

FB:FBrf0190556
PMID:16547170[15]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0055059

asymmetric neuroblast division

FB:FBrf0155600
PMID:12526793[19]

IGI: Inferred from Genetic Interaction

FB:FBgn0001981
FB:FBgn0001983

P

From FB

GO:0070491

repressing transcription factor binding

FB:FBrf0204267
PMID:18309295[4]

IPI: Inferred from Physical Interaction

FB:FBgn0020496

F

From FB

GO:0070491

repressing transcription factor binding

FB:FBrf0204267
PMID:18309295[4]

IPI: Inferred from Physical Interaction

FB:FBgn0023444

F

From FB

contributes_to

GO:0001106

RNA polymerase II transcription corepressor activity

FB:FBrf0204267
PMID:18309295[4]

IPI: Inferred from Physical Interaction

FB:FBgn0023444

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Leptin M (1999) Gastrulation in Drosophila: the logic and the cellular mechanisms. EMBO J 18: 3187-92 PubMed GONUTS page
  2. 2.0 2.1 Postigo AA et al. (1999) zfh-1, the Drosophila homologue of ZEB, is a transcriptional repressor that regulates somatic myogenesis. Mol Cell Biol 19: 7255-63 PubMed GONUTS page
  3. Courey AJ & Jia S (2001) Transcriptional repression: the long and the short of it. Genes Dev 15: 2786-96 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Qi D et al. (2008) Drosophila Ebi mediates Snail-dependent transcriptional repression through HDAC3-induced histone deacetylation. EMBO J 27: 898-909 PubMed GONUTS page
  5. 5.0 5.1 5.2 Kasai Y et al. (1992) Dorsal-ventral patterning in Drosophila: DNA binding of snail protein to the single-minded gene. Proc Natl Acad Sci U S A 89: 3414-8 PubMed GONUTS page
  6. Ashburner M et al. (1999) An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Genetics 153: 179-219 PubMed GONUTS page
  7. 7.0 7.1 Ashraf SI et al. (1999) The mesoderm determinant snail collaborates with related zinc-finger proteins to control Drosophila neurogenesis. EMBO J 18: 6426-38 PubMed GONUTS page
  8. Jack J & Myette G (1999) Mutations that alter the morphology of the malpighian tubules in Drosophila. Dev Genes Evol 209: 546-54 PubMed GONUTS page
  9. Wilson R & Leptin M (2000) Fibroblast growth factor receptor-dependent morphogenesis of the Drosophila mesoderm. Philos Trans R Soc Lond B Biol Sci 355: 891-5 PubMed GONUTS page
  10. Stathopoulos A & Levine M (2002) Dorsal gradient networks in the Drosophila embryo. Dev Biol 246: 57-67 PubMed GONUTS page
  11. Cripps RM & Olson EN (2002) Control of cardiac development by an evolutionarily conserved transcriptional network. Dev Biol 246: 14-28 PubMed GONUTS page
  12. Stainier DY (2002) A glimpse into the molecular entrails of endoderm formation. Genes Dev 16: 893-907 PubMed GONUTS page
  13. Bate M et al. (1999) Development of larval body wall muscles. Int Rev Neurobiol 43: 25-44 PubMed GONUTS page
  14. 14.0 14.1 Lall S & Patel NH (2001) Conservation and divergence in molecular mechanisms of axis formation. Annu Rev Genet 35: 407-37 PubMed GONUTS page
  15. 15.0 15.1 Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
  16. Hemavathy K et al. (2004) The repressor function of snail is required for Drosophila gastrulation and is not replaceable by Escargot or Worniu. Dev Biol 269: 411-20 PubMed GONUTS page
  17. Stathopoulos A & Levine M (2004) Whole-genome analysis of Drosophila gastrulation. Curr Opin Genet Dev 14: 477-84 PubMed GONUTS page
  18. 18.0 18.1 Anderson J et al. (2006) Regulation of the retinal determination gene dachshund in the embryonic head and developing eye of Drosophila. Dev Biol 297: 536-49 PubMed GONUTS page
  19. Cai Y et al. (2003) Apical complex genes control mitotic spindle geometry and relative size of daughter cells in Drosophila neuroblast and pI asymmetric divisions. Cell 112: 51-62 PubMed GONUTS page
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