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FB:sn

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) sn ( synonyms: CG15331, CG1536, CG32858, Fascin, SN, Singed, Sn, fascin, fs(1)A1057, fs(1)K1421, fs(1)K418, fs(1)K473, fs(1)K743, fs(1)M45 )
Protein Name(s) singed,
External Links
FB FBgn0003447

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003779

actin binding

FB:FBrf0132100
PMID:10908588[1]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005737

cytoplasm

FB:FBrf0072754
PMID:8163553[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0007015

actin filament organization

FB:FBrf0132269
PMID:11139280[3]

TAS: Traceable Author Statement

P

From FB

GO:0007163

establishment or maintenance of cell polarity

FB:FBrf0208475
PMID:19592575[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008407

chaeta morphogenesis

FB:FBrf0124316

NAS: Non-traceable Author Statement

P

From FB

GO:0008407

chaeta morphogenesis

FB:FBrf0162188
PMID:12975350[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009913

epidermal cell differentiation

FB:FBrf0191902
PMID:16933974[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0015629

actin cytoskeleton

FB:FBrf0208475
PMID:19592575[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0030034

microvillar actin bundle assembly

FB:FBrf0179480
PMID:15226373[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030036

actin cytoskeleton organization

FB:FBrf0208475
PMID:19592575[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030674

protein binding, bridging

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR022768
InterPro:IPR024703

F

From FB

GO:0035017

cuticle pattern formation

FB:FBrf0191902
PMID:16933974[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035099

hemocyte migration

FB:FBrf0208475
PMID:19592575[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035317

imaginal disc-derived wing hair organization

FB:FBrf0188029
PMID:15917291[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042060

wound healing

FB:FBrf0208475
PMID:19592575[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048477

oogenesis

FB:FBrf0044470
PMID:3089870[9]

TAS: Traceable Author Statement

P

From FB

GO:0048477

oogenesis

FB:FBrf0124316

NAS: Non-traceable Author Statement

P

From FB

GO:0048800

antennal morphogenesis

FB:FBrf0148956
PMID:12070612[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048812

neuron projection morphogenesis

FB:FBrf0191992
PMID:16928862[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051015

actin filament binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR022768
InterPro:IPR024703

F

From FB

GO:0051017

actin filament bundle assembly

FB:FBrf0084901

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051017

actin filament bundle assembly

FB:FBrf0124316

NAS: Non-traceable Author Statement

P

From FB

GO:0051017

actin filament bundle assembly

FB:FBrf0167860
PMID:14517310[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051017

actin filament bundle assembly

FB:FBrf0188029
PMID:15917291[8]

IMP: Inferred from Mutant Phenotype

P

From FB

colocalizes_with

GO:0031941

filamentous actin

FB:FBrf0191902
PMID:16933974[6]

IDA: Inferred from Direct Assay

C

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
  2. Cant K et al. (1994) Drosophila singed, a fascin homolog, is required for actin bundle formation during oogenesis and bristle extension. J Cell Biol 125: 369-80 PubMed GONUTS page
  3. Buszczak M & Cooley L (2000) Eggs to die for: cell death during Drosophila oogenesis. Cell Death Differ 7: 1071-4 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Zanet J et al. (2009) Fascin is required for blood cell migration during Drosophila embryogenesis. Development 136: 2557-65 PubMed GONUTS page
  5. Guild GM et al. (2003) Long continuous actin bundles in Drosophila bristles are constructed by overlapping short filaments. J Cell Biol 162: 1069-77 PubMed GONUTS page
  6. 6.0 6.1 6.2 Chanut-Delalande H et al. (2006) Shavenbaby couples patterning to epidermal cell shape control. PLoS Biol 4: e290 PubMed GONUTS page
  7. Tilney LG et al. (2004) Microvilli appear to represent the first step in actin bundle formation in Drosophila bristles. J Cell Sci 117: 3531-8 PubMed GONUTS page
  8. 8.0 8.1 Guild GM et al. (2005) Actin filament bundles in Drosophila wing hairs: hairs and bristles use different strategies for assembly. Mol Biol Cell 16: 3620-31 PubMed GONUTS page
  9. Perrimon N et al. (1986) X-linked female-sterile loci in Drosophila melanogaster. Genetics 113: 695-712 PubMed GONUTS page
  10. He B & Adler PN (2002) The genetic control of arista lateral morphogenesis in Drosophila. Dev Genes Evol 212: 218-29 PubMed GONUTS page
  11. Kraft R et al. (2006) Phenotypes of Drosophila brain neurons in primary culture reveal a role for fascin in neurite shape and trajectory. J Neurosci 26: 8734-47 PubMed GONUTS page
  12. Tilney LG et al. (2003) Actin filament turnover regulated by cross-linking accounts for the size, shape, location, and number of actin bundles in Drosophila bristles. Mol Biol Cell 14: 3953-66 PubMed GONUTS page
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