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FB:smg
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | smg ( synonyms: CG5263, D69, SMAUG, SMG, Smau, Smaug, Smg, anon-D69, anonD69, dSmaug ) | |
| Protein Name(s) | smaug, | |
| External Links | ||
| FB | FBgn0016070 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000289 |
nuclear-transcribed mRNA poly(A) tail shortening |
FB:FBrf0193114 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000900 |
translation repressor activity, nucleic acid binding |
FB:FBrf0152348 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0000932 |
cytoplasmic mRNA processing body |
FB:FBrf0200920 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0003729 |
mRNA binding |
FB:FBrf0114361 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003729 |
mRNA binding |
FB:FBrf0151177 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0003729 |
mRNA binding |
FB:FBrf0167951 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0003730 |
mRNA 3'-UTR binding |
FB:FBrf0141280 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0003730 |
mRNA 3'-UTR binding |
FB:FBrf0152348 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0003730 |
mRNA 3'-UTR binding |
FB:FBrf0173287 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0200619 |
IPI: Inferred from Physical Interaction |
FB:FBgn0030252 |
F |
From FB |
||
| GO:0005737 |
cytoplasm |
FB:FBrf0111352 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0017148 |
negative regulation of translation |
FB:FBrf0111352 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0017148 |
negative regulation of translation |
FB:FBrf0141280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0017148 |
negative regulation of translation |
FB:FBrf0152348 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0017148 |
negative regulation of translation |
FB:FBrf0173287 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030371 |
translation repressor activity |
FB:FBrf0111352 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0030371 |
translation repressor activity |
FB:FBrf0141280 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0030371 |
translation repressor activity |
FB:FBrf0151177 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0043488 |
regulation of mRNA stability |
FB:FBrf0192711 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051236 |
establishment of RNA localization |
FB:FBrf0183829 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Zaessinger S et al. (2006) Oskar allows nanos mRNA translation in Drosophila embryos by preventing its deadenylation by Smaug/CCR4. Development 133: 4573-83 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Dean KA et al. (2002) Translational repressors in Drosophila. Trends Genet 18: 572-7 PubMed GONUTS page
- ↑ Eulalio A et al. (2007) P-body formation is a consequence, not the cause, of RNA-mediated gene silencing. Mol Cell Biol 27: 3970-81 PubMed GONUTS page
- ↑ Hall TM (2003) SAM breaks its stereotype. Nat Struct Biol 10: 677-9 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Johnstone O & Lasko P (2001) Translational regulation and RNA localization in Drosophila oocytes and embryos. Annu Rev Genet 35: 365-406 PubMed GONUTS page
- ↑ Liu R et al. (2008) Sisyphus, the Drosophila myosin XV homolog, traffics within filopodia transporting key sensory and adhesion cargos. Development 135: 53-63 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Dahanukar A et al. (1999) Smaug, a novel RNA-binding protein that operates a translational switch in Drosophila. Mol Cell 4: 209-18 PubMed GONUTS page
- ↑ Tadros W et al. (2007) SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase. Dev Cell 12: 143-55 PubMed GONUTS page
- ↑ Semotok JL et al. (2005) Smaug recruits the CCR4/POP2/NOT deadenylase complex to trigger maternal transcript localization in the early Drosophila embryo. Curr Biol 15: 284-94 PubMed GONUTS page
