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FB:sls

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) sls ( synonyms: 0020/01, CG18242, CG18245, CG18857, CG1915, CT41299, D-Titin, D-titin, D-titin-KZ, Dtitin, KZ, Ket, Kettin, MCP, Mitotic Chromosomal Protein, SLS, Salimus, Sallimus, Sls, Titin, anon-CREST, d-titin, ket, kettin, l(3)62Ca, l(3)Ca, l(3)S002001, l(3)dre8, l(3)j1D7, l(3)rL182, lethal (3) S002001, lethal(3)62Ca, sal, sam, titin, zormin )
Protein Name(s) sallimus,
External Links
FB FBgn0086906

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000794

condensed nuclear chromosome

FB:FBrf0102442
PMID:9548712[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0003676

nucleic acid binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR012337

F

From FB

GO:0003779

actin binding

FB:FBrf0107406
PMID:9917396[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0003779

actin binding

FB:FBrf0125351
PMID:10669599[3]

IMP: Inferred from Mutant Phenotype

F

From FB

GO:0004687

myosin light chain kinase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q10466

F

From FB

GO:0005875

microtubule associated complex

FB:FBrf0204649
PMID:18433294[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0007062

sister chromatid cohesion

FB:FBrf0131354
PMID:11062264[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007076

mitotic chromosome condensation

FB:FBrf0131354
PMID:11062264[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007498

mesoderm development

FB:FBrf0138533
PMID:11486054[6]

IEP: Inferred from Expression Pattern

P

From FB

GO:0007517

muscle organ development

FB:FBrf0151208
PMID:12111720[7]

TAS: Traceable Author Statement

P

From FB

GO:0007519

skeletal muscle tissue development

FB:FBrf0123034
PMID:10629221[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007519

skeletal muscle tissue development

FB:FBrf0130194
PMID:10934048[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007520

myoblast fusion

FB:FBrf0130194
PMID:10934048[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008307

structural constituent of muscle

FB:FBrf0123034
PMID:10629221[8]

IMP: Inferred from Mutant Phenotype

F

From FB

GO:0016203

muscle attachment

FB:FBrf0123034
PMID:10629221[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030017

sarcomere

FB:FBrf0102442
PMID:9548712[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0030017

sarcomere

FB:FBrf0123034
PMID:10629221[8]

IDA: Inferred from Direct Assay

C

From FB

GO:0030018

Z disc

FB:FBrf0107406
PMID:9917396[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0030018

Z disc

FB:FBrf0125351
PMID:10669599[3]

IMP: Inferred from Mutant Phenotype

C

From FB

GO:0030018

Z disc

FB:FBrf0174356
PMID:15119962[10]

IDA: Inferred from Direct Assay

C

From FB

GO:0030018

Z disc

FB:FBrf0202672
PMID:18199432[11]

IDA: Inferred from Direct Assay

C

From FB

GO:0040011

locomotion

FB:FBrf0123034
PMID:10629221[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045214

sarcomere organization

FB:FBrf0123034
PMID:10629221[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045214

sarcomere organization

FB:FBrf0200911
PMID:17535853[12]

IGI: Inferred from Genetic Interaction

FB:FBgn0014863

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Machado C et al. (1998) Human autoantibodies reveal titin as a chromosomal protein. J Cell Biol 141: 321-33 PubMed GONUTS page
  2. 2.0 2.1 van Straaten M et al. (1999) Association of kettin with actin in the Z-disc of insect flight muscle. J Mol Biol 285: 1549-62 PubMed GONUTS page
  3. 3.0 3.1 Kolmerer B et al. (2000) Sequence and expression of the kettin gene in Drosophila melanogaster and Caenorhabditis elegans. J Mol Biol 296: 435-48 PubMed GONUTS page
  4. Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
  5. 5.0 5.1 Machado C & Andrew DJ (2000) D-Titin: a giant protein with dual roles in chromosomes and muscles. J Cell Biol 151: 639-52 PubMed GONUTS page
  6. Furlong EE et al. (2001) Patterns of gene expression during Drosophila mesoderm development. Science 293: 1629-33 PubMed GONUTS page
  7. Dworak HA & Sink H (2002) Myoblast fusion in Drosophila. Bioessays 24: 591-601 PubMed GONUTS page
  8. 8.0 8.1 8.2 8.3 8.4 8.5 Hakeda S et al. (2000) Requirements of Kettin, a giant muscle protein highly conserved in overall structure in evolution, for normal muscle function, viability, and flight activity of Drosophila. J Cell Biol 148: 101-14 PubMed GONUTS page
  9. 9.0 9.1 Zhang Y et al. (2000) Drosophila D-titin is required for myoblast fusion and skeletal muscle striation. J Cell Sci 113 ( Pt 17): 3103-15 PubMed GONUTS page
  10. Ayme-Southgate A et al. (2004) Assembly of the giant protein projectin during myofibrillogenesis in Drosophila indirect flight muscles. BMC Cell Biol 5: 17 PubMed GONUTS page
  11. Hudson AM et al. (2008) Mononuclear muscle cells in Drosophila ovaries revealed by GFP protein traps. Dev Biol 314: 329-40 PubMed GONUTS page
  12. Clark KA et al. (2007) The Drosophila muscle LIM protein, Mlp84B, cooperates with D-titin to maintain muscle structural integrity. J Cell Sci 120: 2066-77 PubMed GONUTS page
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