Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

FB:slik

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) slik ( synonyms: CG4527, DPlkk1, PLKK1, Plkk/Slik, Plkk1, Polo kinase kinase 1, SLK, Slik, Slik1, Slk, Ste20 kinase, dPlkk/Slik, dPlkk/Slik threonine kinase, polo kinase kinase 1, slk )
Protein Name(s) Sterile20-like kinase,
External Links
FB FBgn0035001

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000910

cytokinesis

FB:FBrf0180064
PMID:15380073[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0004674

protein serine/threonine kinase activity

FB:FBrf0193095
PMID:17060498[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0004702

receptor signaling protein serine/threonine kinase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

protein_id:AAD28717.1

F

From FB

GO:0004702

receptor signaling protein serine/threonine kinase activity

FB:FBrf0132098
PMID:10908587[3]

NAS: Non-traceable Author Statement

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290
InterPro:IPR017441

F

From FB

GO:0006468

protein phosphorylation

FB:FBrf0132098
PMID:10908587[3]

NAS: Non-traceable Author Statement

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0160223

NAS: Non-traceable Author Statement

P

From FB

GO:0006468

protein phosphorylation

FB:FBrf0193095
PMID:17060498[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0008283

cell proliferation

FB:FBrf0167985
PMID:14624240[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0010800

positive regulation of peptidyl-threonine phosphorylation

FB:FBrf0202814
PMID:18207738[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0032879

regulation of localization

FB:FBrf0193095
PMID:17060498[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042801

polo kinase kinase activity

FB:FBrf0160223

NAS: Non-traceable Author Statement

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Echard A et al. (2004) Terminal cytokinesis events uncovered after an RNAi screen. Curr Biol 14: 1685-93 PubMed GONUTS page
  2. 2.0 2.1 2.2 Hughes SC & Fehon RG (2006) Phosphorylation and activity of the tumor suppressor Merlin and the ERM protein Moesin are coordinately regulated by the Slik kinase. J Cell Biol 175: 305-13 PubMed GONUTS page
  3. 3.0 3.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
  4. Hipfner DR & Cohen SM (2003) The Drosophila sterile-20 kinase slik controls cell proliferation and apoptosis during imaginal disc development. PLoS Biol 1: E35 PubMed GONUTS page
  5. Kunda P et al. (2008) Moesin controls cortical rigidity, cell rounding, and spindle morphogenesis during mitosis. Curr Biol 18: 91-101 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox