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FB:sisA

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) sisA ( synonyms: CG1641, sis A, sis a, sis-A, sis-a, sisa, sisterless a )
Protein Name(s) sisterless A,
External Links
FB FBgn0003411

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000981

sequence-specific DNA binding RNA polymerase II transcription factor activity

FB:FBrf0064442
PMID:8370520[1]

ISS: Inferred from Sequence or Structural Similarity

FB:FBgn0001150

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0125416
PMID:10648226[2]

NAS: Non-traceable Author Statement

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0126663

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005515

protein binding

FB:FBrf0187959
PMID:16083904[3]

IPI: Inferred from Physical Interaction

FB:FBgn0025463

F

From FB

GO:0005634

nucleus

FB:FBrf0064442
PMID:8370520[1]

IC: Inferred by Curator

GO:0045944

C

From FB

GO:0005634

nucleus

FB:FBrf0126663

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0007492

endoderm development

FB:FBrf0127377
PMID:10790394[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007496

anterior midgut development

FB:FBrf0127377
PMID:10790394[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007497

posterior midgut development

FB:FBrf0127377
PMID:10790394[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007530

sex determination

FB:FBrf0064442
PMID:8370520[1]

IGI: Inferred from Genetic Interaction

FB:FBgn0003659

P

From FB

GO:0007530

sex determination

FB:FBrf0131266
PMID:11105896[5]

TAS: Traceable Author Statement

P

From FB

GO:0007538

primary sex determination

FB:FBrf0127377
PMID:10790394[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007540

sex determination, establishment of X:A ratio

FB:FBrf0055582
PMID:1525829[6]

TAS: Traceable Author Statement

P

From FB

GO:0007540

sex determination, establishment of X:A ratio

FB:FBrf0125416
PMID:10648226[2]

NAS: Non-traceable Author Statement

P

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0064442
PMID:8370520[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0152056
PMID:12176927[7]

ISS: Inferred from Sequence or Structural Similarity

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Erickson JW & Cline TW (1993) A bZIP protein, sisterless-a, collaborates with bHLH transcription factors early in Drosophila development to determine sex. Genes Dev 7: 1688-702 PubMed GONUTS page
  2. 2.0 2.1 Schütt C & Nöthiger R (2000) Structure, function and evolution of sex-determining systems in Dipteran insects. Development 127: 667-77 PubMed GONUTS page
  3. Möller A et al. (2005) Drosophila BAP60 is an essential component of the Brahma complex, required for gene activation and repression. J Mol Biol 352: 329-37 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Walker JJ et al. (2000) The Drosophila melanogaster sex determination gene sisA is required in yolk nuclei for midgut formation. Genetics 155: 191-202 PubMed GONUTS page
  5. Canon J & Banerjee U (2000) Runt and Lozenge function in Drosophila development. Semin Cell Dev Biol 11: 327-36 PubMed GONUTS page
  6. Younger-Shepherd S et al. (1992) deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination. Cell 70: 911-22 PubMed GONUTS page
  7. Fassler J et al. (2002) B-ZIP proteins encoded by the Drosophila genome: evaluation of potential dimerization partners. Genome Res 12: 1190-200 PubMed GONUTS page
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