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FB:sina

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) sina ( synonyms: CG9949, SEVEN-IN-ABSENTIA, SINA, Seven in absenti, Sina, anon-EST:fe2H7, anon-fast-evolving-2H7, seven-in-absentia, sia )
Protein Name(s) seven in absentia,
External Links
FB FBgn0003410

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000151

ubiquitin ligase complex

FB:FBrf0155951
PMID:12215542[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0004842

ubiquitin-protein ligase activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR013323

F

From FB

GO:0005515

protein binding

FB:FBrf0098364
PMID:9267026[2]

IPI: Inferred from Physical Interaction

FB:FBgn0011217

F

From FB

GO:0005515

protein binding

FB:FBrf0098364
PMID:9267026[2]

IPI: Inferred from Physical Interaction

FB:FBgn0013725

F

From FB

GO:0005515

protein binding

FB:FBrf0131258
PMID:11032805[3]

IPI: Inferred from Physical Interaction

FB:FBgn0013725

F

From FB

GO:0005634

nucleus

FB:FBrf0051381
PMID:2146028[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0123753

NAS: Non-traceable Author Statement

C

From FB

GO:0006508

proteolysis

FB:FBrf0160832
PMID:12850443[5]

TAS: Traceable Author Statement

P

From FB

GO:0006511

ubiquitin-dependent protein catabolic process

FB:FBrf0051381
PMID:2146028[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006511

ubiquitin-dependent protein catabolic process

FB:FBrf0129231

NAS: Non-traceable Author Statement

P

From FB

GO:0007423

sensory organ development

FB:FBrf0138359
PMID:11526076[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007465

R7 cell fate commitment

FB:FBrf0129916
PMID:10929403[7]

TAS: Traceable Author Statement

P

From FB

GO:0007465

R7 cell fate commitment

FB:FBrf0160832
PMID:12850443[5]

TAS: Traceable Author Statement

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001841
InterPro:IPR013010
InterPro:IPR013323

F

From FB

GO:0010498

proteasomal protein catabolic process

FB:FBrf0203040
PMID:17962185[8]

IDA: Inferred from Direct Assay

P

From FB

GO:0016567

protein ubiquitination

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR013323

P

From FB

GO:0043621

protein self-association

FB:FBrf0155951
PMID:12215542[1]

IPI: Inferred from Physical Interaction

FB:FBgn0003410

F

From FB

GO:0045676

regulation of R7 cell differentiation

FB:FBrf0051381
PMID:2146028[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045676

regulation of R7 cell differentiation

FB:FBrf0155951
PMID:12215542[1]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Li S et al. (2002) Phyllopod acts as an adaptor protein to link the sina ubiquitin ligase to the substrate protein tramtrack. Mol Cell Biol 22: 6854-65 PubMed GONUTS page
  2. 2.0 2.1 Tang AH et al. (1997) PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism. Cell 90: 459-67 PubMed GONUTS page
  3. Boulton SJ et al. (2000) A role for Ebi in neuronal cell cycle control. EMBO J 19: 5376-86 PubMed GONUTS page
  4. 4.0 4.1 4.2 Carthew RW & Rubin GM (1990) seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye. Cell 63: 561-77 PubMed GONUTS page
  5. 5.0 5.1 Ou CY et al. (2003) Control of protein degradation by E3 ubiquitin ligases in Drosophila eye development. Trends Genet 19: 382-9 PubMed GONUTS page
  6. Pi H et al. (2001) A dual function of phyllopod in Drosophila external sensory organ development: cell fate specification of sensory organ precursor and its progeny. Development 128: 2699-710 PubMed GONUTS page
  7. Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page
  8. Cooper SE et al. (2008) Two modes of degradation of the tramtrack transcription factors by Siah homologues. J Biol Chem 283: 1076-83 PubMed GONUTS page
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