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FB:sim
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | sim ( synonyms: 0483/09, 0716/08, 0899/14, 0953/08, 1002/10, 1034/02, 1050/13, 1110/04, 1111/10, 1330/08, 1479/04, CG7771, S8, SIM, Sim, Single minded, Single-minded, bHLHe16, l(3)87Ea, l(3)E320, l(3)RD, l(3)S8, l(3)s8, schm, schmal, shm, single minded, singleminded ) | |
| Protein Name(s) | single-minded, | |
| External Links | ||
| FB | FBgn0004666 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000978 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding |
FB:FBrf0098379 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0000982 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity |
FB:FBrf0098379 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0123388 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004871 |
signal transducer activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0190327 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0205312 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005667 |
transcription factor complex |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0205312 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007165 |
signal transduction |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
P |
From FB |
|||
| GO:0007398 |
ectoderm development |
FB:FBrf0148941 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007409 |
axonogenesis |
FB:FBrf0194377 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007411 |
axon guidance |
FB:FBrf0210319 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007417 |
central nervous system development |
FB:FBrf0123388 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007418 |
ventral midline development |
FB:FBrf0053347 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007418 |
ventral midline development |
FB:FBrf0201497 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007419 |
ventral cord development |
FB:FBrf0183858 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007420 |
brain development |
FB:FBrf0158813 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007420 |
brain development |
FB:FBrf0190327 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007628 |
adult walking behavior |
FB:FBrf0151881 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007628 |
adult walking behavior |
FB:FBrf0155654 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035225 |
determination of genital disc primordium |
FB:FBrf0187379 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0040011 |
locomotion |
FB:FBrf0155654 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0043565 |
sequence-specific DNA binding |
FB:FBrf0202405 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0098379 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0046982 |
protein heterodimerization activity |
FB:FBrf0099730 |
IPI: Inferred from Physical Interaction |
FB:FBgn0015014 |
F |
From FB |
||
|
contributes_to |
GO:0001077 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
FB:FBrf0099730 |
IPI: Inferred from Physical Interaction |
FB:FBgn0015014 |
F |
From FB |
|
|
contributes_to |
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0202405 |
IPI: Inferred from Physical Interaction |
FB:FBgn0015014 |
F |
From FB |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Zelzer E et al. (1997) The PAS domain confers target gene specificity of Drosophila bHLH/PAS proteins. Genes Dev 11: 2079-89 PubMed GONUTS page
- ↑ 2.0 2.1 Umetsu D et al. (2006) The highly ordered assembly of retinal axons and their synaptic partners is regulated by Hedgehog/Single-minded in the Drosophila visual system. Development 133: 791-800 PubMed GONUTS page
- ↑ 3.0 3.1 Romero NM et al. (2008) Regulation of the Drosophila hypoxia-inducible factor alpha Sima by CRM1-dependent nuclear export. Mol Cell Biol 28: 3410-23 PubMed GONUTS page
- ↑ Stathopoulos A & Levine M (2002) Dorsal gradient networks in the Drosophila embryo. Dev Biol 246: 57-67 PubMed GONUTS page
- ↑ Grueber WB et al. (2007) Projections of Drosophila multidendritic neurons in the central nervous system: links with peripheral dendrite morphology. Development 134: 55-64 PubMed GONUTS page
- ↑ Berger J et al. (2008) Systematic identification of genes that regulate neuronal wiring in the Drosophila visual system. PLoS Genet 4: e1000085 PubMed GONUTS page
- ↑ Nambu JR et al. (1991) The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development. Cell 67: 1157-67 PubMed GONUTS page
- ↑ Kim SH et al. (2007) CNS midline cells influence the division and survival of lateral glia in the Drosophila nervous system. Genesis 45: 266-74 PubMed GONUTS page
- ↑ Olofsson B & Page DT (2005) Condensation of the central nervous system in embryonic Drosophila is inhibited by blocking hemocyte migration or neural activity. Dev Biol 279: 233-43 PubMed GONUTS page
- ↑ Page DT (2003) A function for Egf receptor signaling in expanding the developing brain in Drosophila. Curr Biol 13: 474-82 PubMed GONUTS page
- ↑ Pielage J et al. (2002) Novel behavioral and developmental defects associated with Drosophila single-minded. Dev Biol 249: 283-99 PubMed GONUTS page
- ↑ 12.0 12.1 Strauss R (2002) The central complex and the genetic dissection of locomotor behaviour. Curr Opin Neurobiol 12: 633-8 PubMed GONUTS page
- ↑ Chen EH et al. (2005) Allocation and specification of the genital disc precursor cells in Drosophila. Dev Biol 281: 270-85 PubMed GONUTS page
- ↑ 14.0 14.1 Jiang L & Crews ST (2007) Transcriptional specificity of Drosophila dysfusion and the control of tracheal fusion cell gene expression. J Biol Chem 282: 28659-68 PubMed GONUTS page
- ↑ 15.0 15.1 Sonnenfeld M et al. (1997) The Drosophila tango gene encodes a bHLH-PAS protein that is orthologous to mammalian Arnt and controls CNS midline and tracheal development. Development 124: 4571-82 PubMed GONUTS page
