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FB:shark
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | shark ( synonyms: CG18247, Dtk7, SHARK, SYK/SHARK, Shark, Src homology 2 ankyrin repeat tyrosine kinase, Src homology 2, ankyrin repeat, tyrosine kinase, Syk, Tk7, Tyrosine kinase 7, dtk7, l(2)W4, l(2R)W4 ) | |
| Protein Name(s) | SH2 ankyrin repeat kinase, | |
| External Links | ||
| FB | FBgn0015295 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004713 |
protein tyrosine kinase activity |
FB:FBrf0090414 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004713 |
protein tyrosine kinase activity |
FB:FBrf0114933 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004713 |
protein tyrosine kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004713 |
protein tyrosine kinase activity |
FB:FBrf0166266 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004713 |
protein tyrosine kinase activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0004715 |
non-membrane spanning protein tyrosine kinase activity |
FB:FBrf0151280 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005524 |
ATP binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0090414 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005938 |
cell cortex |
FB:FBrf0190273 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0090414 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006468 |
protein phosphorylation |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000719 |
P |
From FB |
||
| GO:0007254 |
JNK cascade |
FB:FBrf0126797 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0001291 |
P |
From FB |
||
| GO:0007254 |
JNK cascade |
FB:FBrf0126797 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007254 |
JNK cascade |
FB:FBrf0151280 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007306 |
eggshell chorion assembly |
FB:FBrf0155235 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007306 |
eggshell chorion assembly |
FB:FBrf0167514 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007391 |
dorsal closure |
FB:FBrf0151280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007394 |
dorsal closure, elongation of leading edge cells |
FB:FBrf0126797 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043277 |
apoptotic cell clearance |
FB:FBrf0205492 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043277 |
apoptotic cell clearance |
FB:FBrf0207750 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045199 |
maintenance of epithelial cell apical/basal polarity |
FB:FBrf0090414 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0046843 |
dorsal appendage formation |
FB:FBrf0155235 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0046843 |
dorsal appendage formation |
FB:FBrf0167514 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004884 |
P |
From FB |
||
| GO:0046843 |
dorsal appendage formation |
FB:FBrf0167514 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Ferrante AW Jr et al. (1995) Shark, a Src homology 2, ankyrin repeat, tyrosine kinase, is expressed on the apical surfaces of ectodermal epithelia. Proc Natl Acad Sci U S A 92: 1911-5 PubMed GONUTS page
- ↑ 2.0 2.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
- ↑ Biswas R et al. (2006) Drosophila Dok is required for embryonic dorsal closure. Development 133: 217-27 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Fernandez R et al. (2000) The Drosophila shark tyrosine kinase is required for embryonic dorsal closure. Genes Dev 14: 604-14 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Tran DH & Berg CA (2003) bullwinkle and shark regulate dorsal-appendage morphogenesis in Drosophila oogenesis. Development 130: 6273-82 PubMed GONUTS page
- ↑ Ziegenfuss JS et al. (2008) Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling. Nature 453: 935-9 PubMed GONUTS page
- ↑ Doherty J et al. (2009) Ensheathing glia function as phagocytes in the adult Drosophila brain. J Neurosci 29: 4768-81 PubMed GONUTS page
acd |
d cont.ejm |
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