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FB:rst

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) rst ( synonyms: CG4125, CT13684, ChiasmC-roughest, IREE-C, IRREC/RST, Irre-C, IrreC, IrreC-Rst, IrreC-rst, IrreC/Rst, IrrecC, Irregular chiasm C-roughest protein, Irregular chiasmC-roughest, Irregular optic chiasma C/Roughest, Irregular-chiasm-C, Roughest, Rst, UB883, irreC, irreC-roughest, irreC-rst, irrecC-rst, irregular chiasm C-roughest, irregular chiasm-C-roughest, irregular optic chiasma C, rst-irreC, rst-irrecC, rst/irrecC )
Protein Name(s) roughest,
External Links
FB FBgn0003285

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001745

compound eye morphogenesis

FB:FBrf0190176
PMID:16380111[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001745

compound eye morphogenesis

FB:FBrf0200828
PMID:17428827[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001745

compound eye morphogenesis

FB:FBrf0202887
PMID:18166433[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001745

compound eye morphogenesis

FB:FBrf0211429
PMID:20599904[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0005886

plasma membrane

FB:FBrf0065542
PMID:7503814[5]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005886

plasma membrane

FB:FBrf0119351

NAS: Non-traceable Author Statement

C

From FB

GO:0005886

plasma membrane

FB:FBrf0190176
PMID:16380111[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0005886

plasma membrane

FB:FBrf0208494
PMID:19415632[6]

IDA: Inferred from Direct Assay

C

From FB

GO:0007156

homophilic cell adhesion

FB:FBrf0147184
PMID:12006672[7]

TAS: Traceable Author Statement

P

From FB

GO:0007156

homophilic cell adhesion

FB:FBrf0156100
PMID:12547518[8]

TAS: Traceable Author Statement

P

From FB

GO:0007156

homophilic cell adhesion

FB:FBrf0208193
PMID:19515699[9]

IGI: Inferred from Genetic Interaction

FB:FBgn0029082

P

From FB

GO:0007409

axonogenesis

FB:FBrf0156777

NAS: Non-traceable Author Statement

P

From FB

GO:0007520

myoblast fusion

FB:FBrf0151208
PMID:12111720[10]

TAS: Traceable Author Statement

P

From FB

GO:0016021

integral to membrane

FB:FBrf0156100
PMID:12547518[8]

TAS: Traceable Author Statement

C

From FB

GO:0016021

integral to membrane

FB:FBrf0156777

NAS: Non-traceable Author Statement

C

From FB

GO:0016202

regulation of striated muscle tissue development

FB:FBrf0139637
PMID:11684659[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030165

PDZ domain binding

FB:FBrf0190176
PMID:16380111[1]

IPI: Inferred from Physical Interaction

FB:FBgn0026313

F

From FB

GO:0045177

apical part of cell

FB:FBrf0208494
PMID:19415632[6]

IDA: Inferred from Direct Assay

C

From FB

GO:0046331

lateral inhibition

FB:FBrf0214518

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046666

retinal cell programmed cell death

FB:FBrf0156100
PMID:12547518[8]

TAS: Traceable Author Statement

P

From FB

GO:0046667

compound eye retinal cell programmed cell death

FB:FBrf0147184
PMID:12006672[7]

TAS: Traceable Author Statement

P

From FB

GO:0046667

compound eye retinal cell programmed cell death

FB:FBrf0156777

NAS: Non-traceable Author Statement

P

From FB

GO:0048749

compound eye development

FB:FBrf0160376
PMID:12782271[12]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Vishnu S et al. (2006) The adaptor protein X11Lalpha/Dmint1 interacts with the PDZ-binding domain of the cell recognition protein Rst in Drosophila. Dev Biol 289: 296-307 PubMed GONUTS page
  2. Cordero JB et al. (2007) Dynamic decapentaplegic signaling regulates patterning and adhesion in the Drosophila pupal retina. Development 134: 1861-71 PubMed GONUTS page
  3. Larson DE et al. (2008) Cellular behavior in the developing Drosophila pupal retina. Mech Dev 125: 223-32 PubMed GONUTS page
  4. Bao S et al. (2010) Preferential adhesion maintains separation of ommatidia in the Drosophila eye. Dev Biol 344: 948-56 PubMed GONUTS page
  5. Ramos RG et al. (1993) The irregular chiasm C-roughest locus of Drosophila, which affects axonal projections and programmed cell death, encodes a novel immunoglobulin-like protein. Genes Dev 7: 2533-47 PubMed GONUTS page
  6. 6.0 6.1 Simon CR et al. (2009) Precise temporal regulation of roughest is required for correct salivary gland autophagic cell death in Drosophila. Genesis 47: 492-504 PubMed GONUTS page
  7. 7.0 7.1 Gorski S & Marra M (2002) Programmed cell death takes flight: genetic and genomic approaches to gene discovery in Drosophila. Physiol Genomics 9: 59-69 PubMed GONUTS page
  8. 8.0 8.1 8.2 Brachmann CB & Cagan RL (2003) Patterning the fly eye: the role of apoptosis. Trends Genet 19: 91-6 PubMed GONUTS page
  9. Zhuang S et al. (2009) Sns and Kirre, the Drosophila orthologs of Nephrin and Neph1, direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes. Development 136: 2335-44 PubMed GONUTS page
  10. Dworak HA & Sink H (2002) Myoblast fusion in Drosophila. Bioessays 24: 591-601 PubMed GONUTS page
  11. Strünkelnberg M et al. (2001) rst and its paralogue kirre act redundantly during embryonic muscle development in Drosophila. Development 128: 4229-39 PubMed GONUTS page
  12. Araujo H et al. (2003) Requirement of the roughest gene for differentiation and time of death of interommatidial cells during pupal stages of Drosophila compound eye development. Mech Dev 120: 537-47 PubMed GONUTS page
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