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FB:rhea

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) rhea ( synonyms: CG6831, CT21159, Rhea, Talin, Tln, talin, tendrils )
Protein Name(s) rhea,
External Links
FB FBgn0260442

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001726

ruffle

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR015224

C

From FB

GO:0003779

actin binding

FB:FBrf0132100
PMID:10908588[1]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0003779

actin binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002558

F

From FB

GO:0005158

insulin receptor binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002404

F

From FB

GO:0005200

structural constituent of cytoskeleton

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR015224

F

From FB

GO:0005515

protein binding

FB:FBrf0204247
PMID:18327251[2]

IPI: Inferred from Physical Interaction

FB:FBgn0259745

F

From FB

GO:0005925

focal adhesion

FB:FBrf0129868
PMID:10908592[3]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005925

focal adhesion

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR015224

C

From FB

GO:0006911

phagocytosis, engulfment

FB:FBrf0191376
PMID:16336044[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007016

cytoskeletal anchoring at plasma membrane

FB:FBrf0129868
PMID:10908592[3]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0007016

cytoskeletal anchoring at plasma membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR015224

P

From FB

GO:0007155

cell adhesion

FB:FBrf0155672
PMID:12361595[5]

TAS: Traceable Author Statement

P

From FB

GO:0007155

cell adhesion

FB:FBrf0167741
PMID:14527345[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007475

apposition of dorsal and ventral imaginal disc-derived wing surfaces

FB:FBrf0093664
PMID:9136017[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007526

larval somatic muscle development

FB:FBrf0210226
PMID:20220848[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008360

regulation of cell shape

FB:FBrf0167741
PMID:14527345[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0015629

actin cytoskeleton

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR006077

C

From FB

GO:0016203

muscle attachment

FB:FBrf0093664
PMID:9136017[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035160

maintenance of epithelial integrity, open tracheal system

FB:FBrf0193035
PMID:16720877[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045892

negative regulation of transcription, DNA-dependent

FB:FBrf0188145
PMID:15852002[10]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
  2. Löer B et al. (2008) The NHL-domain protein Wech is crucial for the integrin-cytoskeleton link. Nat Cell Biol 10: 422-8 PubMed GONUTS page
  3. 3.0 3.1 Hynes RO & Zhao Q (2000) The evolution of cell adhesion. J Cell Biol 150: F89-96 PubMed GONUTS page
  4. Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
  5. Bökel C & Brown NH (2002) Integrins in development: moving on, responding to, and sticking to the extracellular matrix. Dev Cell 3: 311-21 PubMed GONUTS page
  6. 6.0 6.1 Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
  7. 7.0 7.1 Prout M et al. (1997) Autosomal mutations affecting adhesion between wing surfaces in Drosophila melanogaster. Genetics 146: 275-85 PubMed GONUTS page
  8. Schnorrer F et al. (2010) Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Nature 464: 287-91 PubMed GONUTS page
  9. Levi BP et al. (2006) Drosophila talin and integrin genes are required for maintenance of tracheal terminal branches and luminal organization. Development 133: 2383-93 PubMed GONUTS page
  10. Bécam IE et al. (2005) Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophila. Nat Cell Biol 7: 510-6 PubMed GONUTS page
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