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FB:rap

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) rap ( synonyms: APC/C(Fzr/Cdh1), CDH1, CG3000, Cdh1, Cdh1/Fzr, Cdh1(Fzr), Cdh(Fzr), Fizzy related, Fizzy-related, Fizzy-related/Cdh1, Fxr, Fzr, Fzr/rap, Hec/Cdh(Fzr), Rap/Fzr, anon-WO03040301.193, cdh1, dFZR, fizzy-related, fzr, l(1)G0326, l(1)G0418, rap/Fzr, rap/fizzy-related, rap/fzr, redax, reduced axons, westfalenexpress, wex )
Protein Name(s) retina aberrant in pattern,
External Links
FB FBgn0262699

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001745

compound eye morphogenesis

FB:FBrf0190151
PMID:16098963[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0005737

cytoplasm

FB:FBrf0212144
PMID:20890296[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005813

centrosome

FB:FBrf0149063
PMID:12082076[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005814

centriole

FB:FBrf0193251
PMID:16814722[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0005814

centriole

FB:FBrf0201218
PMID:17475495[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0005819

spindle

FB:FBrf0149063
PMID:12082076[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0007455

eye-antennal disc morphogenesis

FB:FBrf0190151
PMID:16098963[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008054

cyclin catabolic process

FB:FBrf0098351
PMID:9288747[6]

IDA: Inferred from Direct Assay

P

From FB

GO:0008347

glial cell migration

FB:FBrf0186590

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008347

glial cell migration

FB:FBrf0212144
PMID:20890296[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0010001

glial cell differentiation

FB:FBrf0204641
PMID:18430931[7]

IDA: Inferred from Direct Assay

P

From FB

GO:0030163

protein catabolic process

FB:FBrf0149063
PMID:12082076[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030424

axon

FB:FBrf0212144
PMID:20890296[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0031536

positive regulation of exit from mitosis

FB:FBrf0190151
PMID:16098963[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031536

positive regulation of exit from mitosis

FB:FBrf0195204
PMID:16854973[8]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Pimentel AC & Venkatesh TR (2005) rap gene encodes Fizzy-related protein (Fzr) and regulates cell proliferation and pattern formation in the developing Drosophila eye-antennal disc. Dev Biol 285: 436-46 PubMed GONUTS page
  2. 2.0 2.1 2.2 Silies M & Klämbt C (2010) APC/C(Fzr/Cdh1)-dependent regulation of cell adhesion controls glial migration in the Drosophila PNS. Nat Neurosci 13: 1357-64 PubMed GONUTS page
  3. 3.0 3.1 3.2 Raff JW et al. (2002) The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time. J Cell Biol 157: 1139-49 PubMed GONUTS page
  4. Basto R et al. (2006) Flies without centrioles. Cell 125: 1375-86 PubMed GONUTS page
  5. Peel N et al. (2007) Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation. Curr Biol 17: 834-43 PubMed GONUTS page
  6. Sigrist SJ & Lehner CF (1997) Drosophila fizzy-related down-regulates mitotic cyclins and is required for cell proliferation arrest and entry into endocycles. Cell 90: 671-81 PubMed GONUTS page
  7. Kaplow ME et al. (2008) Regulation of glia number in Drosophila by Rap/Fzr, an activator of the anaphase-promoting complex, and Loco, an RGS protein. Genetics 178: 2003-16 PubMed GONUTS page
  8. Reber A et al. (2006) Terminal mitoses require negative regulation of Fzr/Cdh1 by Cyclin A, preventing premature degradation of mitotic cyclins and String/Cdc25. Development 133: 3201-11 PubMed GONUTS page
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