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FB:pygo

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) pygo ( synonyms: BEST:LD21971, CG11518, Dm Pygo, Pygo, Pygopus, anon-WO02077023.1, dPygo, gam, gammy legs, pNB5.2, pyg, pygopous, pypo )
Protein Name(s) pygopus,
External Links
FB FBgn0043900

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

FB:FBrf0146918
PMID:11955446[1]

IPI: Inferred from Physical Interaction

FB:FBgn0039907

F

From FB

GO:0005634

nucleus

FB:FBrf0145402

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0146918
PMID:11955446[1]

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0147387

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0149129
PMID:11988739[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0174483
PMID:15043810[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0187313
PMID:16005293[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0006351

transcription, DNA-dependent

FB:FBrf0149129
PMID:11988739[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007223

Wnt receptor signaling pathway, calcium modulating pathway

FB:FBrf0146554

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007472

wing disc morphogenesis

FB:FBrf0192456
PMID:16962574[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001965

F

From FB

GO:0009880

embryonic pattern specification

FB:FBrf0149129
PMID:11988739[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0145402

NAS: Non-traceable Author Statement

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0145629

NAS: Non-traceable Author Statement

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0146918
PMID:11955446[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0146918
PMID:11955446[1]

IPI: Inferred from Physical Interaction

FB:FBgn0039907

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0147387

NAS: Non-traceable Author Statement

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0148960
PMID:12015286[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0000117

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0148960
PMID:12015286[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0004009

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0148960
PMID:12015286[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0026597

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0148960
PMID:12015286[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0149129
PMID:11988739[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0000117

P

From FB

GO:0016055

Wnt receptor signaling pathway

FB:FBrf0151913
PMID:12163411[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030177

positive regulation of Wnt receptor signaling pathway

FB:FBrf0146918
PMID:11955446[1]

IGI: Inferred from Genetic Interaction

FB:FBgn0004009

P

From FB

GO:0030177

positive regulation of Wnt receptor signaling pathway

FB:FBrf0146918
PMID:11955446[1]

IGI: Inferred from Genetic Interaction

FB:FBgn0039907

P

From FB

GO:0030177

positive regulation of Wnt receptor signaling pathway

FB:FBrf0204685
PMID:18451032[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035214

eye-antennal disc development

FB:FBrf0174585
PMID:15128670[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

FB:FBrf0174483
PMID:15043810[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0048526

imaginal disc-derived wing expansion

FB:FBrf0192456
PMID:16962574[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048813

dendrite morphogenesis

FB:FBrf0190556
PMID:16547170[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0060232

delamination

FB:FBrf0192456
PMID:16962574[5]

IMP: Inferred from Mutant Phenotype

P

From FB

contributes_to

GO:0001105

RNA polymerase II transcription coactivator activity

FB:FBrf0174483
PMID:15043810[3]

IPI: Inferred from Physical Interaction

FB:FBgn0000117

F

From FB

contributes_to

GO:0001105

RNA polymerase II transcription coactivator activity

FB:FBrf0174483
PMID:15043810[3]

IPI: Inferred from Physical Interaction

FB:FBgn0039907

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Kramps T et al. (2002) Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex. Cell 109: 47-60 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Thompson B et al. (2002) A new nuclear component of the Wnt signalling pathway. Nat Cell Biol 4: 367-73 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Thompson BJ (2004) A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes. Curr Biol 14: 458-66 PubMed GONUTS page
  4. Hoffmans R et al. (2005) Pygopus and legless provide essential transcriptional coactivator functions to armadillo/beta-catenin. Curr Biol 15: 1207-11 PubMed GONUTS page
  5. 5.0 5.1 5.2 Kiger JA Jr et al. (2007) Tissue remodeling during maturation of the Drosophila wing. Dev Biol 301: 178-91 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 Parker DS et al. (2002) Pygopus, a nuclear PHD-finger protein required for Wingless signaling in Drosophila. Development 129: 2565-76 PubMed GONUTS page
  7. Belenkaya TY et al. (2002) pygopus Encodes a nuclear protein essential for wingless/Wnt signaling. Development 129: 4089-101 PubMed GONUTS page
  8. Carrera I et al. (2008) Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13. Proc Natl Acad Sci U S A 105: 6644-9 PubMed GONUTS page
  9. Lin HV et al. (2004) Wingless eliminates ommatidia from the edge of the developing eye through activation of apoptosis. Development 131: 2409-18 PubMed GONUTS page
  10. Parrish JZ et al. (2006) Genome-wide analyses identify transcription factors required for proper morphogenesis of Drosophila sensory neuron dendrites. Genes Dev 20: 820-35 PubMed GONUTS page
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