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FB:pnt
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | pnt ( synonyms: 0123/09, 0608/07, 0998/12, 3520, CG17077, D-Ets-2, D-ets-2, DMPOINT1A, E(E2F)3D, EK3-2, ETS2, EY3-1, Ets at 58AB, Ets protein Pointed P2, Ets2, Ets58AB, Ets94F, PNT-P1, PNTP1, PNTP2, POINT, Pnt, Pnt-P1, PntP1, PntP2, Pointed, Pointed-P1, Pointed2, PointedP2, ets94F, l(3)07825, l(3)j1B7, l(3)s118306, png, pnt-P1, pnt-P2, pntP2, pointed P2, pointed-P1, pointed-P2, pointed-RC, pointedP2, ptd ) | |
| Protein Name(s) | pointed, | |
| External Links | ||
| FB | FBgn0003118 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000981 |
sequence-specific DNA binding RNA polymerase II transcription factor activity |
FB:FBrf0161068 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003700 |
sequence-specific DNA binding transcription factor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
MGI:MGI:95455 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0135901 |
IPI: Inferred from Physical Interaction |
FB:FBgn0023214 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
MGI:MGI:95455 |
C |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0156682 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
MGI:MGI:95455 |
P |
From FB |
||
| GO:0006911 |
phagocytosis, engulfment |
FB:FBrf0191376 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006916 |
anti-apoptosis |
FB:FBrf0105264 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003997 |
P |
From FB |
||
| GO:0007157 |
heterophilic cell-cell adhesion |
FB:FBrf0156682 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007173 |
epidermal growth factor receptor signaling pathway |
FB:FBrf0131266 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007265 |
Ras protein signal transduction |
FB:FBrf0129916 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007362 |
terminal region determination |
FB:FBrf0054989 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003733 |
P |
From FB |
||
| GO:0007422 |
peripheral nervous system development |
FB:FBrf0083410 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007424 |
open tracheal system development |
FB:FBrf0125237 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007426 |
tracheal outgrowth, open tracheal system |
FB:FBrf0190195 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007427 |
epithelial cell migration, open tracheal system |
FB:FBrf0211250 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007428 |
primary branching, open tracheal system |
FB:FBrf0187390 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007429 |
secondary branching, open tracheal system |
FB:FBrf0148947 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007429 |
secondary branching, open tracheal system |
FB:FBrf0167264 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007455 |
eye-antennal disc morphogenesis |
FB:FBrf0192868 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007464 |
R3/R4 cell fate commitment |
FB:FBrf0204109 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007476 |
imaginal disc-derived wing morphogenesis |
FB:FBrf0193945 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007507 |
heart development |
FB:FBrf0151249 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007507 |
heart development |
FB:FBrf0160748 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008284 |
positive regulation of cell proliferation |
FB:FBrf0212840 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008293 |
torso signaling pathway |
FB:FBrf0054989 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003733 |
P |
From FB |
||
| GO:0009997 |
negative regulation of cardioblast cell fate specification |
FB:FBrf0160371 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030707 |
ovarian follicle cell development |
FB:FBrf0128450 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0035225 |
determination of genital disc primordium |
FB:FBrf0187379 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043565 |
sequence-specific DNA binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0045467 |
R7 cell development |
FB:FBrf0129916 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045610 |
regulation of hemocyte differentiation |
FB:FBrf0180639 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0147141 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0161068 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0048190 |
wing disc dorsal/ventral pattern formation |
FB:FBrf0202749 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000242 |
P |
From FB |
||
| GO:0048747 |
muscle fiber development |
FB:FBrf0191368 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0061320 |
pericardial nephrocyte differentiation |
FB:FBrf0160371 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0061331 |
epithelial cell proliferation involved in Malpighian tubule morphogenesis |
FB:FBrf0102951 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0070491 |
repressing transcription factor binding |
FB:FBrf0161068 |
IPI: Inferred from Physical Interaction |
FB:FBgn0023214 |
F |
From FB |
||
|
contributes_to |
GO:0001077 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
FB:FBrf0158889 |
IDA: Inferred from Direct Assay |
F |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Yamada T et al. (2003) EDL/MAE regulates EGF-mediated induction by antagonizing Ets transcription factor Pointed. Development 130: 4085-96 PubMed GONUTS page
- ↑ Baker DA et al. (2001) Mae mediates MAP kinase phosphorylation of Ets transcription factors in Drosophila. Nature 411: 330-4 PubMed GONUTS page
- ↑ Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
- ↑ Kurada P & White K (1998) Ras promotes cell survival in Drosophila by downregulating hid expression. Cell 95: 319-29 PubMed GONUTS page
- ↑ Canon J & Banerjee U (2000) Runt and Lozenge function in Drosophila development. Semin Cell Dev Biol 11: 327-36 PubMed GONUTS page
- ↑ 6.0 6.1 Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page
- ↑ 7.0 7.1 Strecker TR et al. (1991) Zygotic genes that mediate torso receptor tyrosine kinase functions in the Drosophila melanogaster embryo. Proc Natl Acad Sci U S A 88: 5824-8 PubMed GONUTS page
- ↑ Salzberg A et al. (1994) Mutations affecting the pattern of the PNS in Drosophila reveal novel aspects of neuronal development. Neuron 13: 269-87 PubMed GONUTS page
- ↑ Zelzer E & Shilo BZ (2000) Cell fate choices in Drosophila tracheal morphogenesis. Bioessays 22: 219-26 PubMed GONUTS page
- ↑ Cabernard C & Affolter M (2005) Distinct roles for two receptor tyrosine kinases in epithelial branching morphogenesis in Drosophila. Dev Cell 9: 831-42 PubMed GONUTS page
- ↑ Hsouna A et al. (2010) Drosophila von Hippel-Lindau tumor suppressor gene function in epithelial tubule morphogenesis. Mol Cell Biol 30: 3779-94 PubMed GONUTS page
- ↑ Myat MM et al. (2005) A molecular link between FGF and Dpp signaling in branch-specific migration of the Drosophila trachea. Dev Biol 281: 38-52 PubMed GONUTS page
- ↑ Ribeiro C et al. (2002) In vivo imaging reveals different cellular functions for FGF and Dpp signaling in tracheal branching morphogenesis. Dev Cell 2: 677-83 PubMed GONUTS page
- ↑ Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
- ↑ Brown KE et al. (2006) Epithelial cell adhesion in the developing Drosophila retina is regulated by Atonal and the EGF receptor pathway. Dev Biol 300: 710-21 PubMed GONUTS page
- ↑ Weber U et al. (2008) Combinatorial signaling by the Frizzled/PCP and Egfr pathways during planar cell polarity establishment in the Drosophila eye. Dev Biol 316: 110-23 PubMed GONUTS page
- ↑ Dworkin I & Gibson G (2006) Epidermal growth factor receptor and transforming growth factor-beta signaling contributes to variation for wing shape in Drosophila melanogaster. Genetics 173: 1417-31 PubMed GONUTS page
- ↑ Cripps RM & Olson EN (2002) Control of cardiac development by an evolutionarily conserved transcriptional network. Dev Biol 246: 14-28 PubMed GONUTS page
- ↑ Lo PC & Frasch M (2003) Establishing A-P polarity in the embryonic heart tube: a conserved function of Hox genes in Drosophila and vertebrates? Trends Cardiovasc Med 13: 182-7 PubMed GONUTS page
- ↑ Buchon N et al. (2010) Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol 8: 152 PubMed GONUTS page
- ↑ 21.0 21.1 Alvarez AD et al. (2003) pannier and pointedP2 act sequentially to regulate Drosophila heart development. Development 130: 3015-26 PubMed GONUTS page
- ↑ Dobens LL & Raftery LA (2000) Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells. Dev Dyn 218: 80-93 PubMed GONUTS page
- ↑ Chen EH et al. (2005) Allocation and specification of the genital disc precursor cells in Drosophila. Dev Biol 281: 270-85 PubMed GONUTS page
- ↑ Zettervall CJ et al. (2004) A directed screen for genes involved in Drosophila blood cell activation. Proc Natl Acad Sci U S A 101: 14192-7 PubMed GONUTS page
- ↑ Ohshiro T et al. (2002) Ligand-dependent activation of breathless FGF receptor gene in Drosophila developing trachea. Mech Dev 114: 3-11 PubMed GONUTS page
- ↑ Bejarano F et al. (2008) A gain-of-function suppressor screen for genes involved in dorsal-ventral boundary formation in the Drosophila wing. Genetics 178: 307-23 PubMed GONUTS page
- ↑ Dutta D et al. (2005) Drosophila Heartless acts with Heartbroken/Dof in muscle founder differentiation. PLoS Biol 3: e337 PubMed GONUTS page
- ↑ Kerber B et al. (1998) Seven-up, the Drosophila homolog of the COUP-TF orphan receptors, controls cell proliferation in the insect kidney. Genes Dev 12: 1781-6 PubMed GONUTS page
- ↑ Yuasa Y et al. (2003) Drosophila homeodomain protein REPO controls glial differentiation by cooperating with ETS and BTB transcription factors. Development 130: 2419-28 PubMed GONUTS page