GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
FB:pirk
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | pirk ( synonyms: BcDNA:SD16010, CG15678, PGRP-LC-interacting inhibitor of Imd signaling, Pims, Pirk, Rudra, pims, rudra ) | |
| Protein Name(s) | poor Imd response upon knock-in, | |
| External Links | ||
| FB | FBgn0034647 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005102 |
receptor binding |
FB:FBrf0205806 |
IPI: Inferred from Physical Interaction |
FB:FBgn0030695 |
F |
From FB |
||
| GO:0005102 |
receptor binding |
FB:FBrf0205806 |
IPI: Inferred from Physical Interaction |
FB:FBgn0035976 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0205806 |
IPI: Inferred from Physical Interaction |
FB:FBgn0013983 |
F |
From FB |
||
| GO:0009609 |
response to symbiotic bacterium |
FB:FBrf0205850 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045824 |
negative regulation of innate immune response |
FB:FBrf0205850 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050777 |
negative regulation of immune response |
FB:FBrf0205806 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0061060 |
negative regulation of peptidoglycan recognition protein signaling pathway |
FB:FBrf0205806 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Aggarwal K et al. (2008) Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway. PLoS Pathog 4: e1000120 PubMed GONUTS page
- ↑ 2.0 2.1 Lhocine N et al. (2008) PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling. Cell Host Microbe 4: 147-58 PubMed GONUTS page
