Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

FB:pho

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) pho ( synonyms: CG17743, PHO, Peiohomeotic, Pho, Pleiohomeotic, YY1, dYY1, l(4)102EFc, l(4)29, l(4)BU-2, l(4)OC-1, l(4)pho, pleihomeotic, polyhomeotic )
Protein Name(s) pleiohomeotic,
External Links
FB FBgn0002521

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000790

nuclear chromatin

FB:FBrf0111363
PMID:10433918[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0000980

RNA polymerase II distal enhancer sequence-specific DNA binding

FB:FBrf0125319
PMID:10644409[2]

IDA: Inferred from Direct Assay

F

From FB

GO:0003677

DNA binding

FB:FBrf0102896
PMID:9651589[3]

NAS: Non-traceable Author Statement

F

From FB

GO:0003677

DNA binding

FB:FBrf0111363
PMID:10433918[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0003677

DNA binding

FB:FBrf0183709
PMID:15337121[4]

TAS: Traceable Author Statement

F

From FB

GO:0003677

DNA binding

FB:FBrf0190547
PMID:16618800[5]

IDA: Inferred from Direct Assay

F

From FB

GO:0003682

chromatin binding

FB:FBrf0208162
PMID:19478141[6]

IDA: Inferred from Direct Assay

F

From FB

GO:0003682

chromatin binding

FB:FBrf0208740

IDA: Inferred from Direct Assay

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0113498

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0113498

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0190547
PMID:16618800[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0005703

polytene chromosome puff

FB:FBrf0201820
PMID:17921257[7]

IDA: Inferred from Direct Assay

C

From FB

GO:0005704

polytene chromosome band

FB:FBrf0211271
PMID:20627963[8]

IDA: Inferred from Direct Assay

C

From FB

GO:0006265

DNA topological change

FB:FBrf0192516
PMID:17018295[9]

IDA: Inferred from Direct Assay

P

From FB

GO:0006342

chromatin silencing

FB:FBrf0111363
PMID:10433918[1]

IDA: Inferred from Direct Assay

P

From FB

GO:0006342

chromatin silencing

FB:FBrf0190547
PMID:16618800[5]

IDA: Inferred from Direct Assay

P

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0113498

NAS: Non-traceable Author Statement

P

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0201535
PMID:17519021[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR007087
InterPro:IPR015880

F

From FB

GO:0010629

negative regulation of gene expression

FB:FBrf0201820
PMID:17921257[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016458

gene silencing

FB:FBrf0111363
PMID:10433918[1]

NAS: Non-traceable Author Statement

P

From FB

GO:0016458

gene silencing

FB:FBrf0190555
PMID:16077005[11]

IDA: Inferred from Direct Assay

P

From FB

GO:0031011

Ino80 complex

FB:FBrf0190547
PMID:16618800[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0031490

chromatin DNA binding

FB:FBrf0201820
PMID:17921257[7]

IDA: Inferred from Direct Assay

F

From FB

GO:0043565

sequence-specific DNA binding

FB:FBrf0192516
PMID:17018295[9]

IDA: Inferred from Direct Assay

F

From FB

GO:0045892

negative regulation of transcription, DNA-dependent

FB:FBrf0125319
PMID:10644409[2]

IDA: Inferred from Direct Assay

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Fritsch C et al. (1999) The DNA-binding polycomb group protein pleiohomeotic mediates silencing of a Drosophila homeotic gene. Development 126: 3905-13 PubMed GONUTS page
  2. 2.0 2.1 Shimell MJ et al. (2000) Functional analysis of repressor binding sites in the iab-2 regulatory region of the abdominal-A homeotic gene. Dev Biol 218: 38-52 PubMed GONUTS page
  3. Brown JL et al. (1998) The Drosophila Polycomb group gene pleiohomeotic encodes a DNA binding protein with homology to the transcription factor YY1. Mol Cell 1: 1057-64 PubMed GONUTS page
  4. Levine SS et al. (2004) Division of labor in polycomb group repression. Trends Biochem Sci 29: 478-85 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Klymenko T et al. (2006) A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities. Genes Dev 20: 1110-22 PubMed GONUTS page
  6. Gambetta MC et al. (2009) Essential role of the glycosyltransferase sxc/Ogt in polycomb repression. Science 325: 93-6 PubMed GONUTS page
  7. 7.0 7.1 7.2 Beisel C et al. (2007) Comparing active and repressed expression states of genes controlled by the Polycomb/Trithorax group proteins. Proc Natl Acad Sci U S A 104: 16615-20 PubMed GONUTS page
  8. Brown JL & Kassis JA (2010) Spps, a Drosophila Sp1/KLF family member, binds to PREs and is required for PRE activity late in development. Development 137: 2597-602 PubMed GONUTS page
  9. 9.0 9.1 Mohd-Sarip A et al. (2006) Architecture of a polycomb nucleoprotein complex. Mol Cell 24: 91-100 PubMed GONUTS page
  10. Goodliffe JM et al. (2007) Coordinated regulation of Myc trans-activation targets by Polycomb and the Trithorax group protein Ash1. BMC Mol Biol 8: 40 PubMed GONUTS page
  11. Mohd-Sarip A et al. (2005) Synergistic recognition of an epigenetic DNA element by Pleiohomeotic and a Polycomb core complex. Genes Dev 19: 1755-60 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox