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FB:pbl
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | pbl ( synonyms: 0083/20, 0293/09, 0542/03, CG8114, ECT2, GEF, PBL, PEBBLE, Pbl, Pebble, anon-WO0172774.22, anon-WO0172774.25, l(3)09645 ) | |
| Protein Name(s) | pebble, | |
| External Links | ||
| FB | FBgn0003041 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000910 |
cytokinesis |
FB:FBrf0101082 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0106612 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0151414 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0180064 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0180476 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000910 |
cytokinesis |
FB:FBrf0191432 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000915 |
cytokinesis, actomyosin contractile ring assembly |
FB:FBrf0131381 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000915 |
cytokinesis, actomyosin contractile ring assembly |
FB:FBrf0151773 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000915 |
cytokinesis, actomyosin contractile ring assembly |
FB:FBrf0174933 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005085 |
guanyl-nucleotide exchange factor activity |
FB:FBrf0101082 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0005085 |
guanyl-nucleotide exchange factor activity |
FB:FBrf0106612 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005085 |
guanyl-nucleotide exchange factor activity |
FB:FBrf0119294 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
FB:FBrf0131381 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
FB:FBrf0206776 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0101082 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0134594 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0206776 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005938 |
cell cortex |
FB:FBrf0206776 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007110 |
cytokinesis after meiosis I |
FB:FBrf0174933 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007111 |
cytokinesis after meiosis II |
FB:FBrf0174933 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007155 |
cell adhesion |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007399 |
nervous system development |
FB:FBrf0200690 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007422 |
peripheral nervous system development |
FB:FBrf0131381 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007443 |
Malpighian tubule morphogenesis |
FB:FBrf0111391 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007509 |
mesoderm migration involved in gastrulation |
FB:FBrf0179437 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008078 |
mesodermal cell migration |
FB:FBrf0179446 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008360 |
regulation of cell shape |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008360 |
regulation of cell shape |
FB:FBrf0179437 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0022008 |
neurogenesis |
FB:FBrf0214431 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030676 |
Rac guanyl-nucleotide exchange factor activity |
FB:FBrf0206776 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0032154 |
cleavage furrow |
FB:FBrf0206776 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0032314 |
regulation of Rac GTPase activity |
FB:FBrf0206776 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0010333 |
P |
From FB |
||
| GO:0032314 |
regulation of Rac GTPase activity |
FB:FBrf0206776 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0014011 |
P |
From FB |
||
| GO:0045184 |
establishment of protein localization |
FB:FBrf0191432 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0050770 |
regulation of axonogenesis |
FB:FBrf0180582 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0041203 |
P |
From FB |
||
| GO:0051225 |
spindle assembly |
FB:FBrf0174933 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Somma MP et al. (2002) Molecular dissection of cytokinesis by RNA interference in Drosophila cultured cells. Mol Biol Cell 13: 2448-60 PubMed GONUTS page
- ↑ 2.0 2.1 Lee LA & Orr-Weaver TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu Rev Genet 37: 545-78 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
- ↑ Echard A et al. (2004) Terminal cytokinesis events uncovered after an RNAi screen. Curr Biol 14: 1685-93 PubMed GONUTS page
- ↑ Eggert US et al. (2004) Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. PLoS Biol 2: e379 PubMed GONUTS page
- ↑ 6.0 6.1 Dean SO et al. (2005) Distinct pathways control recruitment and maintenance of myosin II at the cleavage furrow during cytokinesis. Proc Natl Acad Sci U S A 102: 13473-8 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Prokopenko SN et al. (2000) Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins. Genetics 156: 1691-715 PubMed GONUTS page
- ↑ Mazumdar A & Mazumdar M (2002) How one becomes many: blastoderm cellularization in Drosophila melanogaster. Bioessays 24: 1012-22 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 Giansanti MG et al. (2004) Genetic dissection of meiotic cytokinesis in Drosophila males. Mol Biol Cell 15: 2509-22 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 10.3 10.4 10.5 10.6 van Impel A et al. (2009) Regulation of the Rac GTPase pathway by the multifunctional Rho GEF Pebble is essential for mesoderm migration in the Drosophila gastrula. Development 136: 813-22 PubMed GONUTS page
- ↑ Gonzalez C & Bornens M (2000) Light, flies and cell division. Workshop: regulation of cell division in Drosophila. EMBO Rep 1: 390-3 PubMed GONUTS page
- ↑ Koizumi K et al. (2007) RNA interference screen to identify genes required for Drosophila embryonic nervous system development. Proc Natl Acad Sci U S A 104: 5626-31 PubMed GONUTS page
- ↑ Jack J & Myette G (1999) Mutations that alter the morphology of the malpighian tubules in Drosophila. Dev Genes Evol 209: 546-54 PubMed GONUTS page
- ↑ 14.0 14.1 Schumacher S et al. (2004) The RhoGEF Pebble is required for cell shape changes during cell migration triggered by the Drosophila FGF receptor Heartless. Development 131: 2631-40 PubMed GONUTS page
- ↑ Smallhorn M et al. (2004) The epithelial-mesenchymal transition of the Drosophila mesoderm requires the Rho GTP exchange factor Pebble. Development 131: 2641-51 PubMed GONUTS page
- ↑ Ng J & Luo L (2004) Rho GTPases regulate axon growth through convergent and divergent signaling pathways. Neuron 44: 779-93 PubMed GONUTS page
