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FB:pav

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) pav ( synonyms: 0934/13, 0973/08, 2A12, 2A12MEL, CG1258, DmKLP1/pav, DmMKLP1, KIF23, Kinesin-6, Mitotic kinesin-like protein 1, Mklp1, PAV, PAV-KLP, PAV-MKLP, PAV/KLP, Pav, Pav KLP, Pav-KLP, Pav-Klp, Pav-klp, PavKLP, Pavarotti, Pavarotti KLP, Pavarotti-KLP, Pavarroti, anon-EST:fe2A12, anon-fast-evolving-2A12, anon2A12, group D, kinesin-6, pav-KLP, pav-Klp )
Protein Name(s) pavarotti,
External Links
FB FBgn0011692

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000910

cytokinesis

FB:FBrf0106047
PMID:9869630[1]

NAS: Non-traceable Author Statement

P

From FB

GO:0000910

cytokinesis

FB:FBrf0151414
PMID:12134082[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000910

cytokinesis

FB:FBrf0167741
PMID:14527345[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000910

cytokinesis

FB:FBrf0180064
PMID:15380073[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000910

cytokinesis

FB:FBrf0180476
PMID:15547975[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000910

cytokinesis

FB:FBrf0191432
PMID:16174742[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000910

cytokinesis

FB:FBrf0200397
PMID:17412918[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000915

cytokinesis, actomyosin contractile ring assembly

FB:FBrf0134594
PMID:11258476[8]

NAS: Non-traceable Author Statement

P

From FB

GO:0000916

contractile ring contraction involved in cell cycle cytokinesis

FB:FBrf0167861
PMID:14517316[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001709

cell fate determination

FB:FBrf0211056
PMID:20516152[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003777

microtubule motor activity

FB:FBrf0132100
PMID:10908588[11]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0003777

microtubule motor activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001752
InterPro:IPR019821

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001752
InterPro:IPR019821

F

From FB

GO:0005634

nucleus

FB:FBrf0167861
PMID:14517316[9]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0211056
PMID:20516152[10]

IDA: Inferred from Direct Assay

C

From FB

GO:0005813

centrosome

FB:FBrf0134594
PMID:11258476[8]

NAS: Non-traceable Author Statement

C

From FB

GO:0005819

spindle

FB:FBrf0134594
PMID:11258476[8]

NAS: Non-traceable Author Statement

C

From FB

GO:0005871

kinesin complex

FB:FBrf0132100
PMID:10908588[11]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0007018

microtubule-based movement

FB:FBrf0132100
PMID:10908588[11]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0007018

microtubule-based movement

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001752
InterPro:IPR019821

P

From FB

GO:0007052

mitotic spindle organization

FB:FBrf0200397
PMID:17412918[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007224

smoothened signaling pathway

FB:FBrf0188527
PMID:15744048[12]

IGI: Inferred from Genetic Interaction

FB:FBgn0003444

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0083410
PMID:8060613[13]

TAS: Traceable Author Statement

P

From FB

GO:0007422

peripheral nervous system development

FB:FBrf0131381
PMID:11102367[14]

NAS: Non-traceable Author Statement

P

From FB

GO:0016321

female meiosis chromosome segregation

FB:FBrf0135802
PMID:11290718[15]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030111

regulation of Wnt receptor signaling pathway

FB:FBrf0211056
PMID:20516152[10]

IGI: Inferred from Genetic Interaction

FB:FBgn0000117

P

From FB

GO:0030111

regulation of Wnt receptor signaling pathway

FB:FBrf0211056
PMID:20516152[10]

IGI: Inferred from Genetic Interaction

FB:FBgn0086356

P

From FB

GO:0030111

regulation of Wnt receptor signaling pathway

FB:FBrf0211056
PMID:20516152[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030496

midbody

FB:FBrf0167861
PMID:14517316[9]

IDA: Inferred from Direct Assay

C

From FB

GO:0032507

maintenance of protein location in cell

FB:FBrf0191432
PMID:16174742[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051298

centrosome duplication

FB:FBrf0212030
PMID:20818332[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051533

positive regulation of NFAT protein import into nucleus

FB:FBrf0201325
PMID:17293345[17]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Glover DM et al. (1998) Polo-like kinases: a team that plays throughout mitosis. Genes Dev 12: 3777-87 PubMed GONUTS page
  2. Somma MP et al. (2002) Molecular dissection of cytokinesis by RNA interference in Drosophila cultured cells. Mol Biol Cell 13: 2448-60 PubMed GONUTS page
  3. Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
  4. Echard A et al. (2004) Terminal cytokinesis events uncovered after an RNAi screen. Curr Biol 14: 1685-93 PubMed GONUTS page
  5. Eggert US et al. (2004) Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. PLoS Biol 2: e379 PubMed GONUTS page
  6. 6.0 6.1 Dean SO et al. (2005) Distinct pathways control recruitment and maintenance of myosin II at the cleavage furrow during cytokinesis. Proc Natl Acad Sci U S A 102: 13473-8 PubMed GONUTS page
  7. 7.0 7.1 Goshima G et al. (2007) Genes required for mitotic spindle assembly in Drosophila S2 cells. Science 316: 417-21 PubMed GONUTS page
  8. 8.0 8.1 8.2 Gonzalez C & Bornens M (2000) Light, flies and cell division. Workshop: regulation of cell division in Drosophila. EMBO Rep 1: 390-3 PubMed GONUTS page
  9. 9.0 9.1 9.2 Minestrini G et al. (2003) Localization of Pavarotti-KLP in living Drosophila embryos suggests roles in reorganizing the cortical cytoskeleton during the mitotic cycle. Mol Biol Cell 14: 4028-38 PubMed GONUTS page
  10. 10.0 10.1 10.2 10.3 10.4 Jones WM et al. (2010) Cytokinesis proteins Tum and Pav have a nuclear role in Wnt regulation. J Cell Sci 123: 2179-89 PubMed GONUTS page
  11. 11.0 11.1 11.2 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
  12. Collins RT & Cohen SM (2005) A genetic screen in Drosophila for identifying novel components of the hedgehog signaling pathway. Genetics 170: 173-84 PubMed GONUTS page
  13. Salzberg A et al. (1994) Mutations affecting the pattern of the PNS in Drosophila reveal novel aspects of neuronal development. Neuron 13: 269-87 PubMed GONUTS page
  14. Prokopenko SN et al. (2000) Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins. Genetics 156: 1691-715 PubMed GONUTS page
  15. Dobie KW et al. (2001) Identification of chromosome inheritance modifiers in Drosophila melanogaster. Genetics 157: 1623-37 PubMed GONUTS page
  16. Müller H et al. (2010) Proteomic and functional analysis of the mitotic Drosophila centrosome. EMBO J 29: 3344-57 PubMed GONUTS page
  17. Gwack Y et al. (2007) Biochemical and functional characterization of Orai proteins. J Biol Chem 282: 16232-43 PubMed GONUTS page
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