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FB:par-6
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | par-6 ( synonyms: CG5884, DPar-6, DPar6, Dm-Par-6, Dm-Par6, DmPAR-6, DmPar-6, DmPar6, Dmpar6, PAR-6, PAR6, Par, Par-6, Par6, dPAR-6, dPar-6, dmPar-6, par, par6 ) | |
| Protein Name(s) | par-6, | |
| External Links | ||
| FB | FBgn0026192 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001738 |
morphogenesis of a polarized epithelium |
FB:FBrf0167430 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0180362 |
IPI: Inferred from Physical Interaction |
FB:FBgn0261873 |
F |
From FB |
||
| GO:0005938 |
cell cortex |
FB:FBrf0174511 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0006469 |
negative regulation of protein kinase activity |
FB:FBrf0207204 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0006911 |
phagocytosis, engulfment |
FB:FBrf0191376 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007155 |
cell adhesion |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007298 |
border follicle cell migration |
FB:FBrf0154638 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007298 |
border follicle cell migration |
FB:FBrf0180163 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007309 |
oocyte axis specification |
FB:FBrf0158832 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007416 |
synapse assembly |
FB:FBrf0179422 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008360 |
regulation of cell shape |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016324 |
apical plasma membrane |
FB:FBrf0167430 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0016332 |
establishment or maintenance of polarity of embryonic epithelium |
FB:FBrf0141669 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0035003 |
subapical complex |
FB:FBrf0155581 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0035003 |
subapical complex |
FB:FBrf0167430 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0045176 |
apical protein localization |
FB:FBrf0156163 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045179 |
apical cortex |
FB:FBrf0141669 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0045179 |
apical cortex |
FB:FBrf0189924 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0045186 |
zonula adherens assembly |
FB:FBrf0141282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045186 |
zonula adherens assembly |
FB:FBrf0167430 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045196 |
establishment or maintenance of neuroblast polarity |
FB:FBrf0141670 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045197 |
establishment or maintenance of epithelial cell apical/basal polarity |
FB:FBrf0141670 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045197 |
establishment or maintenance of epithelial cell apical/basal polarity |
FB:FBrf0158832 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045200 |
establishment of neuroblast polarity |
FB:FBrf0200720 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0055059 |
asymmetric neuroblast division |
FB:FBrf0209035 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004177 |
P |
From FB |
||
| GO:0060446 |
branching involved in open tracheal system development |
FB:FBrf0215238 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Gibson MC & Perrimon N (2003) Apicobasal polarization: epithelial form and function. Curr Opin Cell Biol 15: 747-52 PubMed GONUTS page
- ↑ Wang Q et al. (2004) Tight junction protein Par6 interacts with an evolutionarily conserved region in the amino terminus of PALS1/stardust. J Biol Chem 279: 30715-21 PubMed GONUTS page
- ↑ Bardin AJ et al. (2004) Asymmetric localization and function of cell-fate determinants: a fly's view. Curr Opin Neurobiol 14: 6-14 PubMed GONUTS page
- ↑ Chabu C & Doe CQ (2008) Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression. Development 135: 2739-46 PubMed GONUTS page
- ↑ Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
- ↑ 6.0 6.1 Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
- ↑ Pinheiro EM & Montell DJ (2004) Requirement for Par-6 and Bazooka in Drosophila border cell migration. Development 131: 5243-51 PubMed GONUTS page
- ↑ 8.0 8.1 Ahringer J (2003) Control of cell polarity and mitotic spindle positioning in animal cells. Curr Opin Cell Biol 15: 73-81 PubMed GONUTS page
- ↑ Ruiz-Canada C et al. (2004) New synaptic bouton formation is disrupted by misregulation of microtubule stability in aPKC mutants. Neuron 42: 567-80 PubMed GONUTS page
- ↑ 10.0 10.1 Hong Y et al. (2001) Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts. Nature 414: 634-8 PubMed GONUTS page
- ↑ Médina E et al. (2002) Role of the Crumbs complex in the regulation of junction formation in Drosophila and mammalian epithelial cells. Biol Cell 94: 305-13 PubMed GONUTS page
- ↑ Schaefer M & Knoblich JA (2001) Protein localization during asymmetric cell division. Exp Cell Res 271: 66-74 PubMed GONUTS page
- ↑ Siegrist SE & Doe CQ (2005) Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts. Cell 123: 1323-35 PubMed GONUTS page
- ↑ Tepass U et al. (2001) Epithelial cell polarity and cell junctions in Drosophila. Annu Rev Genet 35: 747-84 PubMed GONUTS page
- ↑ 15.0 15.1 Bachmann A et al. (2001) Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity. Nature 414: 638-43 PubMed GONUTS page
- ↑ Atwood SX et al. (2007) Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6 aPKC. J Cell Sci 120: 3200-6 PubMed GONUTS page
- ↑ Ogawa H et al. (2009) Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions. J Cell Sci 122: 3242-9 PubMed GONUTS page
- ↑ Jones TA & Metzstein MM (2011) A novel function for the PAR complex in subcellular morphogenesis of tracheal terminal cells in Drosophila melanogaster. Genetics 189: 153-64 PubMed GONUTS page
