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FB:pan
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | pan ( synonyms: CG17964, CG32005, CG34403, DTCF, DTcf, Dm Pan, IA5, LEF-1, LEF/TCF, LEF/TCF-1, LEF1, LEF1/TCF, Lef, Lef1, PAN, Pan, Pangolin, T cell factor, T-cell factor, TCF, TCF/LEF, TCF/LEF1, Tcf, Tcf-1, Tcf/LEF, cTCF, d-TCF, dTCF, dTcf, l(4)102ABb, l(4)13, lef1, lethal 13, lymphocyte enhancer binding factor 1/T cell factor, pan.dTCF, tcf ) | |
| Protein Name(s) | pangolin, | |
| External Links | ||
| FB | FBgn0085432 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003705 |
RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity |
FB:FBrf0155487 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0174483 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005667 |
transcription factor complex |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
MGI:MGI:1202879 |
C |
From FB |
||
| GO:0005667 |
transcription factor complex |
FB:FBrf0213249 |
IPI: Inferred from Physical Interaction |
FB:FBgn0263240 |
C |
From FB |
||
| GO:0005875 |
microtubule associated complex |
FB:FBrf0204649 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006355 |
regulation of transcription, DNA-dependent |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
MGI:MGI:1202879 |
P |
From FB |
||
| GO:0007367 |
segment polarity determination |
FB:FBrf0124171 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007435 |
salivary gland morphogenesis |
FB:FBrf0201960 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007476 |
imaginal disc-derived wing morphogenesis |
FB:FBrf0159304 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007500 |
mesodermal cell fate determination |
FB:FBrf0151249 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007507 |
heart development |
FB:FBrf0134876 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007507 |
heart development |
FB:FBrf0151249 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0009880 |
embryonic pattern specification |
FB:FBrf0159304 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0010628 |
positive regulation of gene expression |
FB:FBrf0200192 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
FB:FBrf0124171 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
FB:FBrf0134876 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0019900 |
kinase binding |
FB:FBrf0206511 |
IPI: Inferred from Physical Interaction |
FB:FBgn0035142 |
F |
From FB |
||
| GO:0030111 |
regulation of Wnt receptor signaling pathway |
FB:FBrf0195251 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
FB:FBrf0151280 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0035277 |
spiracle morphogenesis, open tracheal system |
FB:FBrf0187474 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043565 |
sequence-specific DNA binding |
FB:FBrf0131347 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0045610 |
regulation of hemocyte differentiation |
FB:FBrf0180639 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
FB:FBrf0206770 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0155487 |
IEP: Inferred from Expression Pattern |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0174483 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0070491 |
repressing transcription factor binding |
FB:FBrf0213249 |
IPI: Inferred from Physical Interaction |
FB:FBgn0263240 |
F |
From FB |
||
| GO:0072091 |
regulation of stem cell proliferation |
FB:FBrf0205829 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
contributes_to |
GO:0001077 |
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
FB:FBrf0174483 |
IDA: Inferred from Direct Assay |
F |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Han Z et al. (2002) Transcriptional integration of competence modulated by mutual repression generates cell-type specificity within the cardiogenic mesoderm. Dev Biol 252: 225-40 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Thompson BJ (2004) A complex of Armadillo, Legless, and Pygopus coactivates dTCF to activate wingless target genes. Curr Biol 14: 458-66 PubMed GONUTS page
- ↑ 3.0 3.1 Song H et al. (2010) Coop functions as a corepressor of Pangolin and antagonizes Wingless signaling. Genes Dev 24: 881-6 PubMed GONUTS page
- ↑ Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
- ↑ Harris KE & Beckendorf SK (2007) Different Wnt signals act through the Frizzled and RYK receptors during Drosophila salivary gland migration. Development 134: 2017-25 PubMed GONUTS page
- ↑ 6.0 6.1 Schweizer L et al. (2003) Requirement for Pangolin/dTCF in Drosophila Wingless signaling. Proc Natl Acad Sci U S A 100: 5846-51 PubMed GONUTS page
- ↑ 7.0 7.1 Cripps RM & Olson EN (2002) Control of cardiac development by an evolutionarily conserved transcriptional network. Dev Biol 246: 14-28 PubMed GONUTS page
- ↑ 8.0 8.1 Chen JN & Fishman MC (2000) Genetics of heart development. Trends Genet 16: 383-8 PubMed GONUTS page
- ↑ Ward EJ et al. (2006) Border of Notch activity establishes a boundary between the two dorsal appendage tube cell types. Dev Biol 297: 461-70 PubMed GONUTS page
- ↑ Lee W et al. (2009) Homeodomain-interacting protein kinases (Hipks) promote Wnt/Wg signaling through stabilization of beta-catenin/Arm and stimulation of target gene expression. Development 136: 241-51 PubMed GONUTS page
- ↑ Chao AT et al. (2007) The HMG-box transcription factor SoxNeuro acts with Tcf to control Wg/Wnt signaling activity. Development 134: 989-97 PubMed GONUTS page
- ↑ Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
- ↑ Merabet S et al. (2005) Hox-controlled reorganisation of intrasegmental patterning cues underlies Drosophila posterior spiracle organogenesis. Development 132: 3093-102 PubMed GONUTS page
- ↑ Lee HH & Frasch M (2000) Wingless effects mesoderm patterning and ectoderm segmentation events via induction of its downstream target sloppy paired. Development 127: 5497-508 PubMed GONUTS page
- ↑ Zettervall CJ et al. (2004) A directed screen for genes involved in Drosophila blood cell activation. Proc Natl Acad Sci U S A 101: 14192-7 PubMed GONUTS page
- ↑ Dichtel-Danjoy ML et al. (2009) SoxF is part of a novel negative-feedback loop in the wingless pathway that controls proliferation in the Drosophila wing disc. Development 136: 761-9 PubMed GONUTS page
- ↑ Takashima S et al. (2008) The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling. Nature 454: 651-5 PubMed GONUTS page
