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FB:pain

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) pain ( synonyms: CG15860, CT31987, EP2251, PAINLESS, Pain, Painless )
Protein Name(s) painless,
External Links
FB FBgn0060296

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005216

ion channel activity

FB:FBrf0168053
PMID:14624845[1]

TAS: Traceable Author Statement

F

From FB

GO:0005216

ion channel activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

F

From FB

GO:0005262

calcium channel activity

FB:FBrf0127201
PMID:10798390[2]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0006811

ion transport

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

P

From FB

GO:0006816

calcium ion transport

FB:FBrf0127201
PMID:10798390[2]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0007620

copulation

FB:FBrf0208456
PMID:19531155[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007631

feeding behavior

FB:FBrf0189995
PMID:16647259[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008016

regulation of heart contraction

FB:FBrf0211762
PMID:20824071[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009408

response to heat

FB:FBrf0168052
PMID:14585595[6]

TAS: Traceable Author Statement

P

From FB

GO:0009408

response to heat

FB:FBrf0168053
PMID:14624845[1]

TAS: Traceable Author Statement

P

From FB

GO:0009408

response to heat

FB:FBrf0209960
PMID:19995327[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009612

response to mechanical stimulus

FB:FBrf0159724
PMID:12814565[8]

NAS: Non-traceable Author Statement

P

From FB

GO:0016020

membrane

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

C

From FB

GO:0016021

integral to membrane

FB:FBrf0159724
PMID:12814565[8]

NAS: Non-traceable Author Statement

C

From FB

GO:0019233

sensory perception of pain

FB:FBrf0158411

NAS: Non-traceable Author Statement

P

From FB

GO:0019233

sensory perception of pain

FB:FBrf0158765
PMID:12705873[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0019233

sensory perception of pain

FB:FBrf0212295
PMID:21074052[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045924

regulation of female receptivity

FB:FBrf0208456
PMID:19531155[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048060

negative gravitaxis

FB:FBrf0208683
PMID:19666538[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048266

behavioral response to pain

FB:FBrf0209960
PMID:19995327[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0050974

detection of mechanical stimulus involved in sensory perception

FB:FBrf0168053
PMID:14624845[1]

TAS: Traceable Author Statement

P

From FB

GO:0055085

transmembrane transport

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

P

From FB

NOT

GO:0043052

thermotaxis

FB:FBrf0183983
PMID:15681611[12]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Goodman MB (2003) Sensation is painless. Trends Neurosci 26: 643-5 PubMed GONUTS page
  2. 2.0 2.1 Littleton JT & Ganetzky B (2000) Ion channels and synaptic organization: analysis of the Drosophila genome. Neuron 26: 35-43 PubMed GONUTS page
  3. 3.0 3.1 Sakai T et al. (2009) The Drosophila TRPA channel, Painless, regulates sexual receptivity in virgin females. Genes Brain Behav 8: 546-57 PubMed GONUTS page
  4. Al-Anzi B et al. (2006) Response of Drosophila to wasabi is mediated by painless, the fly homolog of mammalian TRPA1/ANKTM1. Curr Biol 16: 1034-40 PubMed GONUTS page
  5. Sénatore S et al. (2010) Response to mechanical stress is mediated by the TRPA channel painless in the Drosophila heart. PLoS Genet 6: PubMed GONUTS page
  6. Zars T (2003) Hot and cold in Drosophila larvae. Trends Neurosci 26: 575-7 PubMed GONUTS page
  7. 7.0 7.1 Aldrich BT et al. (2010) The amnesiac gene is involved in the regulation of thermal nociception in Drosophila melanogaster. J Neurogenet 24: 33-41 PubMed GONUTS page
  8. 8.0 8.1 Montell C (2003) Thermosensation: hot findings make TRPNs very cool. Curr Biol 13: R476-8 PubMed GONUTS page
  9. Tracey WD Jr et al. (2003) painless, a Drosophila gene essential for nociception. Cell 113: 261-73 PubMed GONUTS page
  10. Neely GG et al. (2010) A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Cell 143: 628-38 PubMed GONUTS page
  11. Sun Y et al. (2009) TRPA channels distinguish gravity sensing from hearing in Johnston's organ. Proc Natl Acad Sci U S A 106: 13606-11 PubMed GONUTS page
  12. Rosenzweig M et al. (2005) The Drosophila ortholog of vertebrate TRPA1 regulates thermotaxis. Genes Dev 19: 419-24 PubMed GONUTS page
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