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FB:os
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | os ( synonyms: CG5993, OS, Os, Outstreched, Outstretched, UPD, Unpaired, Unpaired 1, Unpaired/Out-stretched, Upd, Upd1, bdw, bending-wings, l(1)YC43, l(1)YM55, od, odsy, outstreched, outstretched small eye, outstretched-smalleye, sis-C, sis-c, sisC, sisterless c, small-eye, sy, unp, unpaired, unpaired 1, upa, upd, upd1 ) | |
| Protein Name(s) | outstretched, | |
| External Links | ||
| FB | FBgn0004956 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001700 |
embryonic development via the syncytial blastoderm |
FB:FBrf0178966 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0001745 |
compound eye morphogenesis |
FB:FBrf0179489 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003383 |
apical constriction |
FB:FBrf0209348 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0005102 |
receptor binding |
FB:FBrf0141375 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005102 |
receptor binding |
FB:FBrf0151864 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005102 |
receptor binding |
FB:FBrf0178966 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005125 |
cytokine activity |
FB:FBrf0178966 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005576 |
extracellular region |
FB:FBrf0101352 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005576 |
extracellular region |
FB:FBrf0128050 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005576 |
extracellular region |
FB:FBrf0128151 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005576 |
extracellular region |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005576 |
extracellular region |
FB:FBrf0151864 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005576 |
extracellular region |
FB:FBrf0160750 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005576 |
extracellular region |
FB:FBrf0178966 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005578 |
proteinaceous extracellular matrix |
FB:FBrf0128151 |
TAS: Traceable Author Statement |
C |
From FB |
|||
| GO:0005615 |
extracellular space |
FB:FBrf0213214 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006952 |
defense response |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007259 |
JAK-STAT cascade |
FB:FBrf0128050 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007259 |
JAK-STAT cascade |
FB:FBrf0128151 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007259 |
JAK-STAT cascade |
FB:FBrf0133282 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007259 |
JAK-STAT cascade |
FB:FBrf0151864 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007259 |
JAK-STAT cascade |
FB:FBrf0178966 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007298 |
border follicle cell migration |
FB:FBrf0151864 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007298 |
border follicle cell migration |
FB:FBrf0155683 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007350 |
blastoderm segmentation |
FB:FBrf0141375 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007440 |
foregut morphogenesis |
FB:FBrf0174516 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007442 |
hindgut morphogenesis |
FB:FBrf0151948 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007455 |
eye-antennal disc morphogenesis |
FB:FBrf0193730 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007530 |
sex determination |
FB:FBrf0141375 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007538 |
primary sex determination |
FB:FBrf0128050 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007538 |
primary sex determination |
FB:FBrf0128151 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007540 |
sex determination, establishment of X:A ratio |
FB:FBrf0125416 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007616 |
long-term memory |
FB:FBrf0213703 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016015 |
morphogen activity |
FB:FBrf0160750 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0016476 |
regulation of embryonic cell shape |
FB:FBrf0209348 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0017145 |
stem cell division |
FB:FBrf0141753 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0017145 |
stem cell division |
FB:FBrf0141754 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0017145 |
stem cell division |
FB:FBrf0151864 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030707 |
ovarian follicle cell development |
FB:FBrf0155683 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030707 |
ovarian follicle cell development |
FB:FBrf0187473 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0038001 |
paracrine signaling |
FB:FBrf0213113 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0042078 |
germ-line stem cell division |
FB:FBrf0155987 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045177 |
apical part of cell |
FB:FBrf0213214 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0046427 |
positive regulation of JAK-STAT cascade |
FB:FBrf0190126 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0046427 |
positive regulation of JAK-STAT cascade |
FB:FBrf0213113 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0046427 |
positive regulation of JAK-STAT cascade |
FB:FBrf0213113 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003138 |
P |
From FB |
||
| GO:0046427 |
positive regulation of JAK-STAT cascade |
FB:FBrf0213113 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004864 |
P |
From FB |
||
| GO:0046427 |
positive regulation of JAK-STAT cascade |
FB:FBrf0213113 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0016917 |
P |
From FB |
||
| GO:0046427 |
positive regulation of JAK-STAT cascade |
FB:FBrf0213113 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0041184 |
P |
From FB |
||
| GO:0046427 |
positive regulation of JAK-STAT cascade |
FB:FBrf0213113 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0043903 |
P |
From FB |
||
| GO:0046427 |
positive regulation of JAK-STAT cascade |
FB:FBrf0213113 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048103 |
somatic stem cell division |
FB:FBrf0155987 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0060031 |
mediolateral intercalation |
FB:FBrf0209348 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Agaisse H & Perrimon N (2004) The roles of JAK/STAT signaling in Drosophila immune responses. Immunol Rev 198: 72-82 PubMed GONUTS page
- ↑ Tsai YC & Sun YH (2004) Long-range effect of upd, a ligand for Jak/STAT pathway, on cell cycle in Drosophila eye development. Genesis 39: 141-53 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Bertet C et al. (2009) Repression of Wasp by JAK/STAT signalling inhibits medial actomyosin network assembly and apical cell constriction in intercalating epithelial cells. Development 136: 4199-212 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Luo H & Dearolf CR (2001) The JAK/STAT pathway and Drosophila development. Bioessays 23: 1138-47 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 Hombría JC & Brown S (2002) The fertile field of Drosophila Jak/STAT signalling. Curr Biol 12: R569-75 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Jinks TM et al. (2000) The JAK/STAT signaling pathway is required for the initial choice of sexual identity in Drosophila melanogaster. Mol Cell 5: 581-7 PubMed GONUTS page
- ↑ 7.0 7.1 López-Schier H (2003) The polarisation of the anteroposterior axis in Drosophila. Bioessays 25: 781-91 PubMed GONUTS page
- ↑ 8.0 8.1 Van de Bor V et al. (2011) Asymmetric localisation of cytokine mRNA is essential for JAK/STAT activation during cell invasiveness. Development 138: 1383-93 PubMed GONUTS page
- ↑ 9.0 9.1 Xi R et al. (2003) A gradient of JAK pathway activity patterns the anterior-posterior axis of the follicular epithelium. Dev Cell 4: 167-77 PubMed GONUTS page
- ↑ Josten F et al. (2004) Cooperation of JAK/STAT and Notch signaling in the Drosophila foregut. Dev Biol 267: 181-9 PubMed GONUTS page
- ↑ Johansen KA et al. (2003) Localized JAK/STAT signaling is required for oriented cell rearrangement in a tubular epithelium. Development 130: 135-45 PubMed GONUTS page
- ↑ Ekas LA et al. (2006) JAK/STAT signaling promotes regional specification by negatively regulating wingless expression in Drosophila. Development 133: 4721-9 PubMed GONUTS page
- ↑ Schütt C & Nöthiger R (2000) Structure, function and evolution of sex-determining systems in Dipteran insects. Development 127: 667-77 PubMed GONUTS page
- ↑ Copf T et al. (2011) Cytokine signaling through the JAK/STAT pathway is required for long-term memory in Drosophila. Proc Natl Acad Sci U S A 108: 8059-64 PubMed GONUTS page
- ↑ Kiger AA et al. (2001) Stem cell self-renewal specified by JAK-STAT activation in response to a support cell cue. Science 294: 2542-5 PubMed GONUTS page
- ↑ Tulina N & Matunis E (2001) Control of stem cell self-renewal in Drosophila spermatogenesis by JAK-STAT signaling. Science 294: 2546-9 PubMed GONUTS page
- ↑ Medioni C & Noselli S (2005) Dynamics of the basement membrane in invasive epithelial clusters in Drosophila. Development 132: 3069-77 PubMed GONUTS page
- ↑ 18.0 18.1 18.2 18.3 18.4 18.5 18.6 18.7 Wright VM et al. (2011) Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3. Cell Signal 23: 920-7 PubMed GONUTS page
- ↑ 19.0 19.1 Lin H (2002) The stem-cell niche theory: lessons from flies. Nat Rev Genet 3: 931-40 PubMed GONUTS page
- ↑ Hombría JC et al. (2005) Characterisation of Upd2, a Drosophila JAK/STAT pathway ligand. Dev Biol 288: 420-33 PubMed GONUTS page
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