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FB:orb
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | orb ( synonyms: 151666_s_at, CG10868, ORB, Orb, fs(3)00107, oo18, oo18 RNA binding ) | |
| Protein Name(s) | oo18 RNA-binding protein, | |
| External Links | ||
| FB | FBgn0004882 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0000578 |
embryonic axis specification |
FB:FBrf0141280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0003729 |
mRNA binding |
FB:FBrf0129923 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003729 |
mRNA binding |
FB:FBrf0141280 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0155723 |
IPI: Inferred from Physical Interaction |
FB:FBgn0000114 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0155723 |
IPI: Inferred from Physical Interaction |
FB:FBgn0000182 |
F |
From FB |
||
| GO:0005737 |
cytoplasm |
FB:FBrf0107609 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006378 |
mRNA polyadenylation |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From FB |
|||
| GO:0006378 |
mRNA polyadenylation |
FB:FBrf0155723 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007281 |
germ cell development |
FB:FBrf0145112 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007281 |
germ cell development |
FB:FBrf0145112 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007294 |
germarium-derived oocyte fate determination |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007294 |
germarium-derived oocyte fate determination |
FB:FBrf0141280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007294 |
germarium-derived oocyte fate determination |
FB:FBrf0145112 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007309 |
oocyte axis specification |
FB:FBrf0141280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007310 |
oocyte dorsal/ventral axis specification |
FB:FBrf0076496 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007310 |
oocyte dorsal/ventral axis specification |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007310 |
oocyte dorsal/ventral axis specification |
FB:FBrf0183880 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007314 |
oocyte anterior/posterior axis specification |
FB:FBrf0076496 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007314 |
oocyte anterior/posterior axis specification |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007315 |
pole plasm assembly |
FB:FBrf0091199 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0008298 |
intracellular mRNA localization |
FB:FBrf0103246 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008298 |
intracellular mRNA localization |
FB:FBrf0141280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0017131 |
uridine-rich cytoplasmic polyadenylylation element binding |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0045451 |
pole plasm oskar mRNA localization |
FB:FBrf0076496 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045451 |
pole plasm oskar mRNA localization |
FB:FBrf0107500 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045451 |
pole plasm oskar mRNA localization |
FB:FBrf0132358 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0045451 |
pole plasm oskar mRNA localization |
FB:FBrf0141280 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045451 |
pole plasm oskar mRNA localization |
FB:FBrf0160777 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045727 |
positive regulation of translation |
FB:FBrf0103246 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0046011 |
regulation of oskar mRNA translation |
FB:FBrf0132358 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0046011 |
regulation of oskar mRNA translation |
FB:FBrf0155723 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046012 |
positive regulation of oskar mRNA translation |
FB:FBrf0157336 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0048134 |
germ-line cyst formation |
FB:FBrf0132360 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0132358 |
TAS: Traceable Author Statement |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Johnstone O & Lasko P (2001) Translational regulation and RNA localization in Drosophila oocytes and embryos. Annu Rev Genet 35: 365-406 PubMed GONUTS page
- ↑ Lasko P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J Cell Biol 150: F51-6 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Castagnetti S & Ephrussi A (2003) Orb and a long poly(A) tail are required for efficient oskar translation at the posterior pole of the Drosophila oocyte. Development 130: 835-43 PubMed GONUTS page
- ↑ Bhat KM (1999) The posterior determinant gene nanos is required for the maintenance of the adult germline stem cells during Drosophila oogenesis. Genetics 151: 1479-92 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Manheim EA et al. (2002) Cytoplasmic localization and evolutionary conservation of MEI-218, a protein required for meiotic crossing-over in Drosophila. Mol Biol Cell 13: 84-95 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 Deng W & Lin H (2001) Asymmetric germ cell division and oocyte determination during Drosophila oogenesis. Int Rev Cytol 203: 93-138 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Christerson LB & McKearin DM (1994) orb is required for anteroposterior and dorsoventral patterning during Drosophila oogenesis. Genes Dev 8: 614-28 PubMed GONUTS page
- ↑ Costa A et al. (2005) The Drosophila fragile X protein functions as a negative regulator in the orb autoregulatory pathway. Dev Cell 8: 331-42 PubMed GONUTS page
- ↑ Williamson A & Lehmann R (1996) Germ cell development in Drosophila. Annu Rev Cell Dev Biol 12: 365-91 PubMed GONUTS page
- ↑ 10.0 10.1 Cooperstock RL & Lipshitz HD (1997) Control of mRNA stability and translation during Drosophila development. Semin Cell Dev Biol 8: 541-9 PubMed GONUTS page
- ↑ Wylie C (1999) Germ cells. Cell 96: 165-74 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 Mahowald AP (2001) Assembly of the Drosophila germ plasm. Int Rev Cytol 203: 187-213 PubMed GONUTS page
- ↑ Martin SG et al. (2003) The identification of novel genes required for Drosophila anteroposterior axis formation in a germline clone screen using GFP-Staufen. Development 130: 4201-15 PubMed GONUTS page
- ↑ Leatherman JL & Jongens TA (2003) Transcriptional silencing and translational control: key features of early germline development. Bioessays 25: 326-35 PubMed GONUTS page
