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FB:olf186-F

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) olf186-F ( synonyms: BcDNA:LD03241, CG11430, CRAC modulator 1, CRACM1, Olf186-F, Orai, SPH206, dOrai, dOrai1, dorai, l(2)k11505, lethal (2) k11505 )
Protein Name(s) olf186-F,
External Links
FB FBgn0041585

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0002115

store-operated calcium entry

FB:FBrf0208231
PMID:19515818[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007399

nervous system development

FB:FBrf0200690
PMID:17376868[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0015279

store-operated calcium channel activity

FB:FBrf0201325
PMID:17293345[3]

IMP: Inferred from Mutant Phenotype

F

From FB

GO:0016021

integral to membrane

FB:FBrf0191240
PMID:16582901[4]

NAS: Non-traceable Author Statement

C

From FB

GO:0032234

regulation of calcium ion transport via store-operated calcium channel activity

FB:FBrf0193508
PMID:16645049[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0032236

positive regulation of calcium ion transport via store-operated calcium channel activity

FB:FBrf0201325
PMID:17293345[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051533

positive regulation of NFAT protein import into nucleus

FB:FBrf0191240
PMID:16582901[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051533

positive regulation of NFAT protein import into nucleus

FB:FBrf0201325
PMID:17293345[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051928

positive regulation of calcium ion transport

FB:FBrf0191240
PMID:16582901[4]

IMP: Inferred from Mutant Phenotype

P

From FB

NOT

GO:0004252

serine-type endopeptidase activity

FB:FBrf0155784
PMID:12568721[6]

NAS: Non-traceable Author Statement

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Venkiteswaran G & Hasan G (2009) Intracellular Ca2+ signaling and store-operated Ca2+ entry are required in Drosophila neurons for flight. Proc Natl Acad Sci U S A 106: 10326-31 PubMed GONUTS page
  2. Koizumi K et al. (2007) RNA interference screen to identify genes required for Drosophila embryonic nervous system development. Proc Natl Acad Sci U S A 104: 5626-31 PubMed GONUTS page
  3. 3.0 3.1 3.2 Gwack Y et al. (2007) Biochemical and functional characterization of Orai proteins. J Biol Chem 282: 16232-43 PubMed GONUTS page
  4. 4.0 4.1 4.2 Feske S et al. (2006) A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 441: 179-85 PubMed GONUTS page
  5. Vig M et al. (2006) CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry. Science 312: 1220-3 PubMed GONUTS page
  6. Ross J et al. (2003) Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships. Gene 304: 117-31 PubMed GONUTS page
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