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FB:nwk
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | nwk ( synonyms: CG43479, CG4641, CG4684, NWK, Nervous Wreck, Nervous wreck, Nwk ) | |
| Protein Name(s) | nervous wreck, | |
| External Links | ||
| FB | FBgn0263456 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005070 |
SH3/SH2 adaptor activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
EMBL:U85781 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0213353 |
IPI: Inferred from Physical Interaction |
FB:FBgn0034265 |
F |
From FB |
||
| GO:0007274 |
neuromuscular synaptic transmission |
FB:FBrf0175021 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008582 |
regulation of synaptic growth at neuromuscular junction |
FB:FBrf0204925 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008582 |
regulation of synaptic growth at neuromuscular junction |
FB:FBrf0205746 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030833 |
regulation of actin filament polymerization |
FB:FBrf0205746 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0045886 |
negative regulation of synaptic growth at neuromuscular junction |
FB:FBrf0175021 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045886 |
negative regulation of synaptic growth at neuromuscular junction |
FB:FBrf0213353 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0034265 |
P |
From FB |
||
| GO:0055037 |
recycling endosome |
FB:FBrf0213353 |
IMP: Inferred from Mutant Phenotype |
C |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Rodal AA et al. (2011) A presynaptic endosomal trafficking pathway controls synaptic growth signaling. J Cell Biol 193: 201-17 PubMed GONUTS page
- ↑ 2.0 2.1 Coyle IP et al. (2004) Nervous wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila. Neuron 41: 521-34 PubMed GONUTS page
- ↑ O'Connor-Giles KM et al. (2008) Nervous wreck interacts with thickveins and the endocytic machinery to attenuate retrograde BMP signaling during synaptic growth. Neuron 58: 507-18 PubMed GONUTS page
- ↑ 4.0 4.1 Rodal AA et al. (2008) Nervous wreck and Cdc42 cooperate to regulate endocytic actin assembly during synaptic growth. J Neurosci 28: 8316-25 PubMed GONUTS page
