Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

FB:norpA

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) norpA ( synonyms: CG3620, CdkA, DIP2, MRE18, NORPA, Norp A, NorpA, PI-PLC, PLC, PLC-beta, PLCbeta, Phospholipase C-beta, anon-EST:Posey221, mRNA-like ncRNA in embryogenesis 18, no receptor potential, no receptor potentials A, no-receptor potential A, no-receptor-potential-A, nofC, phospholipase C, phospholipase C-beta, phospholipase Cbeta, phospholipase-C, rof, x12, x13, x16, x24 )
Protein Name(s) no receptor potential A,
External Links
FB FBgn0262738

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001580

detection of chemical stimulus involved in sensory perception of bitter taste

FB:FBrf0210738
PMID:20404155[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0002385

mucosal immune response

FB:FBrf0207552
PMID:19289084[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0004435

phosphatidylinositol phospholipase C activity

FB:FBrf0086225
PMID:8570597[3]

TAS: Traceable Author Statement

F

From FB

GO:0004435

phosphatidylinositol phospholipase C activity

FB:FBrf0123569

NAS: Non-traceable Author Statement

F

From FB

GO:0004435

phosphatidylinositol phospholipase C activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001192
InterPro:IPR001711
InterPro:IPR009535
InterPro:IPR016280

F

From FB

GO:0004629

phospholipase C activity

FB:FBrf0123143
PMID:10611962[4]

TAS: Traceable Author Statement

F

From FB

GO:0005096

GTPase activator activity

FB:FBrf0141625
PMID:11707492[5]

NAS: Non-traceable Author Statement

F

From FB

GO:0005509

calcium ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR009535
InterPro:IPR011992
InterPro:IPR016280

F

From FB

GO:0005624

membrane fraction

FB:FBrf0073876
PMID:7969889[6]

IDA: Inferred from Direct Assay

C

From FB

GO:0006644

phospholipid metabolic process

FB:FBrf0141625
PMID:11707492[5]

TAS: Traceable Author Statement

P

From FB

GO:0006651

diacylglycerol biosynthetic process

FB:FBrf0123143
PMID:10611962[4]

TAS: Traceable Author Statement

P

From FB

GO:0006651

diacylglycerol biosynthetic process

FB:FBrf0141625
PMID:11707492[5]

TAS: Traceable Author Statement

P

From FB

GO:0007602

phototransduction

FB:FBrf0123143
PMID:10611962[4]

TAS: Traceable Author Statement

P

From FB

GO:0007602

phototransduction

FB:FBrf0123569

NAS: Non-traceable Author Statement

P

From FB

GO:0007602

phototransduction

FB:FBrf0187818
PMID:15883198[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007608

sensory perception of smell

FB:FBrf0079271

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008344

adult locomotory behavior

FB:FBrf0187324
PMID:16111941[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008377

light-induced release of internally sequestered calcium ion

FB:FBrf0086225
PMID:8570597[3]

TAS: Traceable Author Statement

P

From FB

GO:0008654

phospholipid biosynthetic process

FB:FBrf0123143
PMID:10611962[4]

TAS: Traceable Author Statement

P

From FB

GO:0009586

rhodopsin mediated phototransduction

FB:FBrf0202587
PMID:18184564[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0009649

entrainment of circadian clock

FB:FBrf0187310
PMID:16085487[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016027

inaD signaling complex

FB:FBrf0105321
PMID:9796815[11]

IPI: Inferred from Physical Interaction

FB:FBgn0001263

C

From FB

GO:0016027

inaD signaling complex

FB:FBrf0160593
PMID:12765677[12]

TAS: Traceable Author Statement

C

From FB

GO:0016028

rhabdomere

FB:FBrf0054343
PMID:1662208[13]

IDA: Inferred from Direct Assay

C

From FB

GO:0016028

rhabdomere

FB:FBrf0190947
PMID:16301334[14]

IDA: Inferred from Direct Assay

C

From FB

GO:0016059

deactivation of rhodopsin mediated signaling

FB:FBrf0202587
PMID:18184564[9]

IDA: Inferred from Direct Assay

P

From FB

GO:0019722

calcium-mediated signaling

FB:FBrf0123143
PMID:10611962[4]

TAS: Traceable Author Statement

P

From FB

GO:0035556

intracellular signal transduction

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000909
InterPro:IPR001192
InterPro:IPR001711

P

From FB

GO:0043052

thermotaxis

FB:FBrf0213227
PMID:21393546[15]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045494

photoreceptor cell maintenance

FB:FBrf0191981
PMID:16835270[16]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046488

phosphatidylinositol metabolic process

FB:FBrf0048396
PMID:3129419[17]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046673

negative regulation of compound eye retinal cell programmed cell death

FB:FBrf0167807
PMID:14724249[18]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051482

elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger

FB:FBrf0086225
PMID:8570597[3]

TAS: Traceable Author Statement

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Kim SH et al. (2010) Drosophila TRPA1 channel mediates chemical avoidance in gustatory receptor neurons. Proc Natl Acad Sci U S A 107: 8440-5 PubMed GONUTS page
  2. Ha EM et al. (2009) Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity. Dev Cell 16: 386-97 PubMed GONUTS page
  3. 3.0 3.1 3.2 Zuker CS (1996) The biology of vision of Drosophila. Proc Natl Acad Sci U S A 93: 571-6 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Montell C (1999) Visual transduction in Drosophila. Annu Rev Cell Dev Biol 15: 231-68 PubMed GONUTS page
  5. 5.0 5.1 5.2 Hardie RC (2001) Phototransduction in Drosophila melanogaster. J Exp Biol 204: 3403-9 PubMed GONUTS page
  6. McKay RR et al. (1994) Membrane association of phospholipase C encoded by the norpA gene of Drosophila melanogaster. Neuroscience 61: 141-8 PubMed GONUTS page
  7. LaLonde MM et al. (2005) Regulation of phototransduction responsiveness and retinal degeneration by a phospholipase D-generated signaling lipid. J Cell Biol 169: 471-9 PubMed GONUTS page
  8. Pick S & Strauss R (2005) Goal-driven behavioral adaptations in gap-climbing Drosophila. Curr Biol 15: 1473-8 PubMed GONUTS page
  9. 9.0 9.1 Wang T et al. (2008) The SOCS box protein STOPS is required for phototransduction through its effects on phospholipase C. Neuron 57: 56-68 PubMed GONUTS page
  10. Glaser FT & Stanewsky R (2005) Temperature synchronization of the Drosophila circadian clock. Curr Biol 15: 1352-63 PubMed GONUTS page
  11. Scott K & Zuker CS (1998) Assembly of the Drosophila phototransduction cascade into a signalling complex shapes elementary responses. Nature 395: 805-8 PubMed GONUTS page
  12. Harteneck C (2003) Proteins modulating TRP channel function. Cell Calcium 33: 303-10 PubMed GONUTS page
  13. Schneuwly S et al. (1991) Properties of photoreceptor-specific phospholipase C encoded by the norpA gene of Drosophila melanogaster. J Biol Chem 266: 24314-9 PubMed GONUTS page
  14. Wang T et al. (2005) Dissecting independent channel and scaffolding roles of the Drosophila transient receptor potential channel. J Cell Biol 171: 685-94 PubMed GONUTS page
  15. Shen WL et al. (2011) Function of rhodopsin in temperature discrimination in Drosophila. Science 331: 1333-6 PubMed GONUTS page
  16. Orem NR et al. (2006) An essential role for endocytosis of rhodopsin through interaction of visual arrestin with the AP-2 adaptor. J Cell Sci 119: 3141-8 PubMed GONUTS page
  17. Inoue H et al. (1988) Membrane-associated phospholipase C of Drosophila retina. J Biochem 103: 91-4 PubMed GONUTS page
  18. Hsu CD et al. (2004) Limited role of developmental programmed cell death pathways in Drosophila norpA retinal degeneration. J Neurosci 24: 500-7 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox