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FB:neur
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | neur ( synonyms: 0328/12, 0971/15, 1293/09, 1315/05, BEST:LD21494, CG11988, Neur, Neuralised, Neuralized, l(3)j6B12, l(3)j9B8, l(3)j9B9, l(3)j9C8, l(3)neo37, neu, neuralised ) | |
| Protein Name(s) | neuralized, | |
| External Links | ||
| FB | FBgn0002932 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001964 |
startle response |
FB:FBrf0205756 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0002121 |
inter-male aggressive behavior |
FB:FBrf0208496 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003677 |
DNA binding |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
FB:FBrf0141437 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0004842 |
ubiquitin-protein ligase activity |
FB:FBrf0141465 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0123920 |
NAS: Non-traceable Author Statement |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0160719 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0130180 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0141437 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005886 |
plasma membrane |
FB:FBrf0193514 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007398 |
ectoderm development |
FB:FBrf0053362 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007399 |
nervous system development |
FB:FBrf0129916 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007399 |
nervous system development |
FB:FBrf0134543 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007422 |
peripheral nervous system development |
FB:FBrf0083410 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007422 |
peripheral nervous system development |
FB:FBrf0134543 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007423 |
sensory organ development |
FB:FBrf0130180 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007476 |
imaginal disc-derived wing morphogenesis |
FB:FBrf0187469 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007498 |
mesoderm development |
FB:FBrf0053362 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008104 |
protein localization |
FB:FBrf0188062 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0008356 |
asymmetric cell division |
FB:FBrf0174511 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008593 |
regulation of Notch signaling pathway |
FB:FBrf0187489 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016360 |
sensory organ precursor cell fate determination |
FB:FBrf0130180 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016360 |
sensory organ precursor cell fate determination |
FB:FBrf0187469 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030707 |
ovarian follicle cell development |
FB:FBrf0128450 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0030718 |
germ-line stem cell maintenance |
FB:FBrf0194773 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0031987 |
locomotion involved in locomotory behavior |
FB:FBrf0205756 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0042048 |
olfactory behavior |
FB:FBrf0192106 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045314 |
regulation of compound eye photoreceptor development |
FB:FBrf0174357 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045747 |
positive regulation of Notch signaling pathway |
FB:FBrf0174511 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0045747 |
positive regulation of Notch signaling pathway |
FB:FBrf0180078 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0046331 |
lateral inhibition |
FB:FBrf0214518 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0046532 |
regulation of photoreceptor cell differentiation |
FB:FBrf0174357 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048471 |
perinuclear region of cytoplasm |
FB:FBrf0160719 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0048749 |
compound eye development |
FB:FBrf0129916 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0048749 |
compound eye development |
FB:FBrf0135929 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048854 |
brain morphogenesis |
FB:FBrf0205756 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
|
colocalizes_with |
GO:0005768 |
endosome |
FB:FBrf0193514 |
IDA: Inferred from Direct Assay |
C |
From FB |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Yamamoto A et al. (2008) Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster. Proc Natl Acad Sci U S A 105: 12393-8 PubMed GONUTS page
- ↑ Edwards AC et al. (2009) Mutations in many genes affect aggressive behavior in Drosophila melanogaster. BMC Biol 7: 29 PubMed GONUTS page
- ↑ 3.0 3.1 Yeh E et al. (2001) Neuralized functions as an E3 ubiquitin ligase during Drosophila development. Curr Biol 11: 1675-9 PubMed GONUTS page
- ↑ Lai EC et al. (2001) Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta. Dev Cell 1: 783-94 PubMed GONUTS page
- ↑ 5.0 5.1 Le Borgne R & Schweisguth F (2003) Unequal segregation of Neuralized biases Notch activation during asymmetric cell division. Dev Cell 5: 139-48 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Yeh E et al. (2000) Neuralized functions cell autonomously to regulate Drosophila sense organ development. EMBO J 19: 4827-37 PubMed GONUTS page
- ↑ 7.0 7.1 Commisso C & Boulianne GL (2007) The NHR1 domain of Neuralized binds Delta and mediates Delta trafficking and Notch signaling. Mol Biol Cell 18: 1-13 PubMed GONUTS page
- ↑ 8.0 8.1 Corbin V et al. (1991) A role for the Drosophila neurogenic genes in mesoderm differentiation. Cell 67: 311-23 PubMed GONUTS page
- ↑ 9.0 9.1 Kumar JP & Moses K (2000) Cell fate specification in the Drosophila retina. Results Probl Cell Differ 31: 93-114 PubMed GONUTS page
- ↑ 10.0 10.1 Lai EC & Rubin GM (2001) neuralized functions cell-autonomously to regulate a subset of notch-dependent processes during adult Drosophila development. Dev Biol 231: 217-33 PubMed GONUTS page
- ↑ Salzberg A et al. (1994) Mutations affecting the pattern of the PNS in Drosophila reveal novel aspects of neuronal development. Neuron 13: 269-87 PubMed GONUTS page
- ↑ 12.0 12.1 Lai EC et al. (2005) The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development 132: 2319-32 PubMed GONUTS page
- ↑ Roegiers F et al. (2005) Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs. Mol Biol Cell 16: 3480-7 PubMed GONUTS page
- ↑ 14.0 14.1 Bardin AJ et al. (2004) Asymmetric localization and function of cell-fate determinants: a fly's view. Curr Opin Neurobiol 14: 6-14 PubMed GONUTS page
- ↑ Wang W & Struhl G (2005) Distinct roles for Mind bomb, Neuralized and Epsin in mediating DSL endocytosis and signaling in Drosophila. Development 132: 2883-94 PubMed GONUTS page
- ↑ Dobens LL & Raftery LA (2000) Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells. Dev Dyn 218: 80-93 PubMed GONUTS page
- ↑ Ward EJ et al. (2006) Stem cells signal to the niche through the Notch pathway in the Drosophila ovary. Curr Biol 16: 2352-8 PubMed GONUTS page
- ↑ Sambandan D et al. (2006) Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. Genetics 174: 1349-63 PubMed GONUTS page
- ↑ 19.0 19.1 Li Y & Baker NE (2004) The roles of cis-inactivation by Notch ligands and of neuralized during eye and bristle patterning in Drosophila. BMC Dev Biol 4: 5 PubMed GONUTS page
- ↑ Betschinger J & Knoblich JA (2004) Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates. Curr Biol 14: R674-85 PubMed GONUTS page
- ↑ Lai EC & Rubin GM (2001) Neuralized is essential for a subset of Notch pathway-dependent cell fate decisions during Drosophila eye development. Proc Natl Acad Sci U S A 98: 5637-42 PubMed GONUTS page
