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Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | nej ( synonyms: CBP, CBP/Nejire, CBP/p300, CBP_, CG15319, CG15321, CREB binding protein, CREB-binding protein, Cbp, Crbp, Cyclic AMP Response Element Binding protein, Drosophila CREB-binding, Drosophila CREB-binding protein, Nej, Nejire, anon-WO0147981.11, anon-WO03040301.89, cbp, dCBP, dKAT3, dmCBP, l(1)G0112, l(1)G0350, l(1)G0470, lethal (1) G0112, lethal (1) G0350, lethal (1) G0470, nej CBP, p300, p300/CBP, protein ) | |
| Protein Name(s) | nejire, | |
| External Links | ||
| FB | FBgn0261617 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000076 |
DNA replication checkpoint |
FB:FBrf0193226 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000123 |
histone acetyltransferase complex |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
C |
From FB |
|||
| GO:0001745 |
compound eye morphogenesis |
FB:FBrf0180303 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0003713 |
transcription coactivator activity |
FB:FBrf0084865 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0003713 |
transcription coactivator activity |
FB:FBrf0105495 |
ISS: Inferred from Sequence or Structural Similarity |
MGI:MGI:1098280 |
F |
From FB |
||
| GO:0003713 |
transcription coactivator activity |
FB:FBrf0125204 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004859 |
F |
From FB |
||
| GO:0003713 |
transcription coactivator activity |
FB:FBrf0202091 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0003713 |
transcription coactivator activity |
FB:FBrf0202091 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003068 |
F |
From FB |
||
| GO:0004402 |
histone acetyltransferase activity |
FB:FBrf0147156 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0005515 |
protein binding |
FB:FBrf0145203 |
IPI: Inferred from Physical Interaction |
FB:FBgn0002780 |
F |
From FB |
||
| GO:0005515 |
protein binding |
FB:FBrf0202091 |
IPI: Inferred from Physical Interaction |
FB:FBgn0023076 |
F |
From FB |
||
| GO:0005634 |
nucleus |
FB:FBrf0084865 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0127222 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005634 |
nucleus |
FB:FBrf0145203 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0007088 |
regulation of mitosis |
FB:FBrf0160535 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0002914 |
P |
From FB |
||
| GO:0007088 |
regulation of mitosis |
FB:FBrf0160535 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007224 |
smoothened signaling pathway |
FB:FBrf0125204 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007224 |
smoothened signaling pathway |
FB:FBrf0135164 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0007269 |
neurotransmitter secretion |
FB:FBrf0127222 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007416 |
synapse assembly |
FB:FBrf0127222 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007464 |
R3/R4 cell fate commitment |
FB:FBrf0180303 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0008134 |
transcription factor binding |
FB:FBrf0125204 |
IPI: Inferred from Physical Interaction |
FB:FBgn0004859 |
F |
From FB |
||
| GO:0008140 |
cAMP response element binding protein binding |
FB:FBrf0127222 |
TAS: Traceable Author Statement |
F |
From FB |
|||
| GO:0008270 |
zinc ion binding |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0008347 |
glial cell migration |
FB:FBrf0214270 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0016055 |
Wnt receptor signaling pathway |
FB:FBrf0135164 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0022008 |
neurogenesis |
FB:FBrf0214431 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030097 |
hemopoiesis |
FB:FBrf0167476 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0032922 |
circadian regulation of gene expression |
FB:FBrf0202091 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043234 |
protein complex |
FB:FBrf0145203 |
IPI: Inferred from Physical Interaction |
FB:FBgn0002780 |
C |
From FB |
||
| GO:0043971 |
histone H3-K18 acetylation |
FB:FBrf0208543 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0043974 |
histone H3-K27 acetylation |
FB:FBrf0208543 |
IDA: Inferred from Direct Assay |
P |
From FB |
|||
| GO:0043982 |
histone H4-K8 acetylation |
FB:FBrf0147156 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043983 |
histone H4-K12 acetylation |
FB:FBrf0147156 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0043993 |
histone acetyltransferase activity (H3-K18 specific) |
FB:FBrf0208543 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0044017 |
histone acetyltransferase activity (H3-K27 specific) |
FB:FBrf0208543 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0045466 |
R7 cell differentiation |
FB:FBrf0180303 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045475 |
locomotor rhythm |
FB:FBrf0202091 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0125204 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004859 |
P |
From FB |
||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
FB:FBrf0125204 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048749 |
compound eye development |
FB:FBrf0211742 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Smolik S & Jones K (2007) Drosophila dCBP is involved in establishing the DNA replication checkpoint. Mol Cell Biol 27: 135-46 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Kumar JP et al. (2004) CREB binding protein functions during successive stages of eye development in Drosophila. Genetics 168: 877-93 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Chen Y et al. (2000) Cubitus interruptus requires Drosophila CREB-binding protein to activate wingless expression in the Drosophila embryo. Mol Cell Biol 20: 1616-25 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Hung HC et al. (2007) Circadian transcription depends on limiting amounts of the transcription co-activator nejire/CBP. J Biol Chem 282: 31349-57 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Ludlam WH et al. (2002) The acetyltransferase activity of CBP is required for wingless activation and H4 acetylation in Drosophila melanogaster. Mol Cell Biol 22: 3832-41 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Bantignies F et al. (2002) The interaction between the coactivator dCBP and Modulo, a chromatin-associated factor, affects segmentation and melanotic tumor formation in Drosophila. Proc Natl Acad Sci U S A 99: 2895-900 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Marek KW et al. (2000) A genetic analysis of synaptic development: pre- and postsynaptic dCBP control transmitter release at the Drosophila NMJ. Neuron 25: 537-47 PubMed GONUTS page
- ↑ 8.0 8.1 Fung SM et al. (2003) MYB and CBP: physiological relevance of a biochemical interaction. Mech Dev 120: 711-20 PubMed GONUTS page
- ↑ 9.0 9.1 Fry CJ & Peterson CL (2001) Chromatin remodeling enzymes: who's on first? Curr Biol 11: R185-97 PubMed GONUTS page
- ↑ Schmidt I et al. (2011) Transcriptional regulation of peripheral glial cell differentiation in the embryonic nervous system of Drosophila. Glia 59: 1264-72 PubMed GONUTS page
- ↑ Evans CJ et al. (2003) Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis. Dev Cell 5: 673-90 PubMed GONUTS page
- ↑ 12.0 12.1 12.2 12.3 Tie F et al. (2009) CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing. Development 136: 3131-41 PubMed GONUTS page
- ↑ Mallik M & Lakhotia SC (2010) Improved activities of CREB binding protein, heterogeneous nuclear ribonucleoproteins and proteasome following downregulation of noncoding hsromega transcripts help suppress poly(Q) pathogenesis in fly models. Genetics 184: 927-45 PubMed GONUTS page
