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FB:ncd

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) ncd ( synonyms: CG7831, Claret nondisjunctional, DmNCD, DmNcd, KIFC1, Kinesin-14, NCD, Ncd, Nonclaret disjunctional, ca, ca(nd), kinesin-14, l(3)05884, ndc, non-claret disjunction, non-claret-disjunctional, nonclaret disjunction, nonclaret disjunctional )
Protein Name(s) non-claret disjunctional,
External Links
FB FBgn0002924

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000022

mitotic spindle elongation

FB:FBrf0190017
PMID:16303556[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000212

meiotic spindle organization

FB:FBrf0092442
PMID:9044053[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0001578

microtubule bundle formation

FB:FBrf0194476
PMID:17141610[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0003777

microtubule motor activity

FB:FBrf0132100
PMID:10908588[4]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0003777

microtubule motor activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001752
InterPro:IPR019821

F

From FB

GO:0005524

ATP binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001752
InterPro:IPR019821

F

From FB

GO:0005819

spindle

FB:FBrf0092442
PMID:9044053[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005871

kinesin complex

FB:FBrf0132100
PMID:10908588[4]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005872

minus-end kinesin complex

FB:FBrf0123738

NAS: Non-traceable Author Statement

C

From FB

GO:0007018

microtubule-based movement

FB:FBrf0132100
PMID:10908588[4]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0007051

spindle organization

FB:FBrf0188049
PMID:15888542[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007052

mitotic spindle organization

FB:FBrf0200397
PMID:17412918[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007056

spindle assembly involved in female meiosis

FB:FBrf0173285
PMID:14635256[7]

NAS: Non-traceable Author Statement

P

From FB

GO:0007059

chromosome segregation

FB:FBrf0123738

NAS: Non-traceable Author Statement

P

From FB

GO:0007059

chromosome segregation

FB:FBrf0206245
PMID:18957509[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007100

mitotic centrosome separation

FB:FBrf0112035
PMID:10559864[9]

IGI: Inferred from Genetic Interaction

FB:FBgn0004378

P

From FB

GO:0007100

mitotic centrosome separation

FB:FBrf0112035
PMID:10559864[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008569

minus-end-directed microtubule motor activity

FB:FBrf0102159
PMID:9484596[10]

NAS: Non-traceable Author Statement

F

From FB

GO:0008569

minus-end-directed microtubule motor activity

FB:FBrf0123738

NAS: Non-traceable Author Statement

F

From FB

GO:0031534

minus-end directed microtubule sliding

FB:FBrf0194476
PMID:17141610[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0032837

distributive segregation

FB:FBrf0058607
PMID:8349113[11]

IGI: Inferred from Genetic Interaction

FB:FBgn0000152

P

From FB

GO:0032837

distributive segregation

FB:FBrf0058607
PMID:8349113[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0032888

regulation of mitotic spindle elongation

FB:FBrf0206245
PMID:18957509[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042803

protein homodimerization activity

FB:FBrf0194476
PMID:17141610[3]

IDA: Inferred from Direct Assay

F

From FB

GO:0051297

centrosome organization

FB:FBrf0212030
PMID:20818332[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051298

centrosome duplication

FB:FBrf0212030
PMID:20818332[12]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0090306

spindle assembly involved in meiosis

FB:FBrf0206245
PMID:18957509[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0090307

spindle assembly involved in mitosis

FB:FBrf0206245
PMID:18957509[8]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Goshima G et al. (2005) Length control of the metaphase spindle. Curr Biol 15: 1979-88 PubMed GONUTS page
  2. 2.0 2.1 Komma DJ & Endow SA (1997) Enhancement of the ncdD microtubule motor mutant by mutants of alpha Tub67C. J Cell Sci 110 ( Pt 2): 229-37 PubMed GONUTS page
  3. 3.0 3.1 3.2 Tao L et al. (2006) A homotetrameric kinesin-5, KLP61F, bundles microtubules and antagonizes Ncd in motility assays. Curr Biol 16: 2293-302 PubMed GONUTS page
  4. 4.0 4.1 4.2 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
  5. Morales-Mulia S & Scholey JM (2005) Spindle pole organization in Drosophila S2 cells by dynein, abnormal spindle protein (Asp), and KLP10A. Mol Biol Cell 16: 3176-86 PubMed GONUTS page
  6. Goshima G et al. (2007) Genes required for mitotic spindle assembly in Drosophila S2 cells. Science 316: 417-21 PubMed GONUTS page
  7. Endow SA (2003) Kinesin motors as molecular machines. Bioessays 25: 1212-9 PubMed GONUTS page
  8. 8.0 8.1 8.2 8.3 Hallen MA et al. (2008) Ncd motor binding and transport in the spindle. J Cell Sci 121: 3834-41 PubMed GONUTS page
  9. 9.0 9.1 Sharp DJ et al. (1999) Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryos. Nat Cell Biol 1: 51-4 PubMed GONUTS page
  10. Hirokawa N et al. (1998) Kinesin and dynein superfamily proteins in organelle transport and cell division. Curr Opin Cell Biol 10: 60-73 PubMed GONUTS page
  11. 11.0 11.1 Whyte WL et al. (1993) The genetic analysis of achiasmate segregation in Drosophila melanogaster. III. The wild-type product of the Axs gene is required for the meiotic segregation of achiasmate homologs. Genetics 134: 825-35 PubMed GONUTS page
  12. 12.0 12.1 Müller H et al. (2010) Proteomic and functional analysis of the mitotic Drosophila centrosome. EMBO J 29: 3344-57 PubMed GONUTS page
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