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FB:mys

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) mys ( synonyms: BetaPS, BetaPS integrin, BetaPS-Int, CG1560, CT40473, EM28, Integrin, Integrin betaPS, Integrin-betaPS, MAb6G11, Myospheroid, Mys, PS, PS integrin beta subunit, PS-beta-integrin, PS((beta)), PSbeta, PSbeta-integrin, bPS, b((PS)), beta PS integrin, beta integrin, beta-Int, beta-Integrin, beta-PS, beta-PS Integrin, beta-PS integrin, beta-PS-Integrin, beta-PS1 integrin, beta-int, beta-integrin, beta1, beta1 integrin, betaIntegrin, betaPS, betaPS Int, betaPS integrin, betaPS-integrin, betaPS.*integrin, betaPS1, beta((PS)), beta((PS)) integrin, beta((PS))-integrin, beta((P))S, beta((mys)), beta((mys))-integrin, betamys, betaps-integrin, integrin PSbeta, integrin beta((PS)), integrin beta((PS)) subunit, integrin-betaPS, l(1)7Db, l(1)7Dn, l(1)93p, l(1)968, l(1)DA551, l(1)EM28, l(1)G0233, l(1)G0281, l(1)mys, lethal myospheroid, lethal(1)93 pupal, lethal(1)myospheroid, myo-spheroid, myospheriod, nj42, non-jumper-42, olfC, olfactory C, olfactory-C )
Protein Name(s) myospheroid,
External Links
FB FBgn0004657

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004872

receptor activity

FB:FBrf0129868
PMID:10908592[1]

TAS: Traceable Author Statement

F

From FB

GO:0004872

receptor activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR012896
InterPro:IPR014836
InterPro:IPR015812
InterPro:IPR016201

F

From FB

GO:0005886

plasma membrane

FB:FBrf0210975

IDA: Inferred from Direct Assay

C

From FB

GO:0005925

focal adhesion

FB:FBrf0129868
PMID:10908592[1]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0006930

substrate-dependent cell migration, cell extension

FB:FBrf0192108
PMID:16818452[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0021873

P

From FB

GO:0007155

cell adhesion

FB:FBrf0167741
PMID:14527345[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007157

heterophilic cell-cell adhesion

FB:FBrf0129868
PMID:10908592[1]

TAS: Traceable Author Statement

P

From FB

GO:0007160

cell-matrix adhesion

FB:FBrf0129868
PMID:10908592[1]

TAS: Traceable Author Statement

P

From FB

GO:0007160

cell-matrix adhesion

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR002369
InterPro:IPR012896
InterPro:IPR014836
InterPro:IPR015812

P

From FB

GO:0007229

integrin-mediated signaling pathway

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR012896
InterPro:IPR014836
InterPro:IPR015812

P

From FB

GO:0007391

dorsal closure

FB:FBrf0110443
PMID:10449347[4]

TAS: Traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0149002
PMID:12000787[5]

TAS: Traceable Author Statement

P

From FB

GO:0007391

dorsal closure

FB:FBrf0151280
PMID:12147138[6]

TAS: Traceable Author Statement

P

From FB

GO:0007411

axon guidance

FB:FBrf0149077
PMID:12040052[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007417

central nervous system development

FB:FBrf0049500
PMID:2492244[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007426

tracheal outgrowth, open tracheal system

FB:FBrf0167264
PMID:14570584[9]

TAS: Traceable Author Statement

P

From FB

GO:0007427

epithelial cell migration, open tracheal system

FB:FBrf0144739
PMID:11835274[10]

TAS: Traceable Author Statement

P

From FB

GO:0007475

apposition of dorsal and ventral imaginal disc-derived wing surfaces

FB:FBrf0167428
PMID:14519396[11]

NAS: Non-traceable Author Statement

P

From FB

GO:0007494

midgut development

FB:FBrf0129746
PMID:10936444[12]

TAS: Traceable Author Statement

P

From FB

GO:0007517

muscle organ development

FB:FBrf0049500
PMID:2492244[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007608

sensory perception of smell

FB:FBrf0159056
PMID:12696671[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008305

integrin complex

FB:FBrf0110443
PMID:10449347[4]

NAS: Non-traceable Author Statement

C

From FB

GO:0008305

integrin complex

FB:FBrf0123537

NAS: Non-traceable Author Statement

C

From FB

GO:0008305

integrin complex

FB:FBrf0129868
PMID:10908592[1]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0008305

integrin complex

FB:FBrf0167428
PMID:14519396[11]

NAS: Non-traceable Author Statement

C

From FB

GO:0008305

integrin complex

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR012896
InterPro:IPR014836
InterPro:IPR015812

C

From FB

GO:0008340

determination of adult lifespan

FB:FBrf0167279
PMID:14570233[14]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008360

regulation of cell shape

FB:FBrf0167741
PMID:14527345[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016203

muscle attachment

FB:FBrf0129746
PMID:10936444[12]

TAS: Traceable Author Statement

P

From FB

GO:0016339

calcium-dependent cell-cell adhesion

FB:FBrf0129868
PMID:10908592[1]

TAS: Traceable Author Statement

P

From FB

GO:0016340

calcium-dependent cell-matrix adhesion

FB:FBrf0129868
PMID:10908592[1]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0016477

cell migration

FB:FBrf0129746
PMID:10936444[12]

TAS: Traceable Author Statement

P

From FB

GO:0030718

germ-line stem cell maintenance

FB:FBrf0209165
PMID:19797664[15]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031252

cell leading edge

FB:FBrf0184059
PMID:15596544[16]

IDA: Inferred from Direct Assay

C

From FB

GO:0031589

cell-substrate adhesion

FB:FBrf0211018
PMID:20371600[17]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035099

hemocyte migration

FB:FBrf0192108
PMID:16818452[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0004636

P

From FB

GO:0035099

hemocyte migration

FB:FBrf0192108
PMID:16818452[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0021873

P

From FB

GO:0035160

maintenance of epithelial integrity, open tracheal system

FB:FBrf0193035
PMID:16720877[18]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048803

imaginal disc-derived male genitalia morphogenesis

FB:FBrf0210522
PMID:20152825[19]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0050839

cell adhesion molecule binding

FB:FBrf0129868
PMID:10908592[1]

TAS: Traceable Author Statement

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Hynes RO & Zhao Q (2000) The evolution of cell adhesion. J Cell Biol 150: F89-96 PubMed GONUTS page
  2. 2.0 2.1 2.2 Huelsmann S et al. (2006) The PDZ-GEF dizzy regulates cell shape of migrating macrophages via Rap1 and integrins in the Drosophila embryo. Development 133: 2915-24 PubMed GONUTS page
  3. 3.0 3.1 Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
  4. 4.0 4.1 Noselli S & Agnès F (1999) Roles of the JNK signaling pathway in Drosophila morphogenesis. Curr Opin Genet Dev 9: 466-72 PubMed GONUTS page
  5. Van Aelst L & Symons M (2002) Role of Rho family GTPases in epithelial morphogenesis. Genes Dev 16: 1032-54 PubMed GONUTS page
  6. Harden N (2002) Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila. Differentiation 70: 181-203 PubMed GONUTS page
  7. Stevens A & Jacobs JR (2002) Integrins regulate responsiveness to slit repellent signals. J Neurosci 22: 4448-55 PubMed GONUTS page
  8. 8.0 8.1 de la Pompa JL et al. (1989) Genetic analysis of muscle development in Drosophila melanogaster. Dev Biol 131: 439-54 PubMed GONUTS page
  9. Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
  10. Rosin D & Shilo BZ (2002) Branch-specific migration cues in the Drosophila tracheal system. Bioessays 24: 110-3 PubMed GONUTS page
  11. 11.0 11.1 Brower DL (2003) Platelets with wings: the maturation of Drosophila integrin biology. Curr Opin Cell Biol 15: 607-13 PubMed GONUTS page
  12. 12.0 12.1 12.2 Brown NH (2000) Cell-cell adhesion via the ECM: integrin genetics in fly and worm. Matrix Biol 19: 191-201 PubMed GONUTS page
  13. Ayyub C & Paranjape J (2002) Genetic interactions provide evidence for the role of integrins in specifying normal olfactory behavior in Drosophila melanogaster. J Neurogenet 16: 165-74 PubMed GONUTS page
  14. Goddeeris MM et al. (2003) Delayed behavioural aging and altered mortality in Drosophila beta integrin mutants. Aging Cell 2: 257-64 PubMed GONUTS page
  15. Issigonis M et al. (2009) JAK-STAT signal inhibition regulates competition in the Drosophila testis stem cell niche. Science 326: 153-6 PubMed GONUTS page
  16. Kadrmas JL et al. (2004) The integrin effector PINCH regulates JNK activity and epithelial migration in concert with Ras suppressor 1. J Cell Biol 167: 1019-24 PubMed GONUTS page
  17. Zhang L et al. (2010) An O-glycosyltransferase promotes cell adhesion during development by influencing secretion of an extracellular matrix integrin ligand. J Biol Chem 285: 19491-501 PubMed GONUTS page
  18. Levi BP et al. (2006) Drosophila talin and integrin genes are required for maintenance of tracheal terminal branches and luminal organization. Development 133: 2383-93 PubMed GONUTS page
  19. Fraichard S et al. (2010) Tenectin is a novel alphaPS2betaPS integrin ligand required for wing morphogenesis and male genital looping in Drosophila. Dev Biol 340: 504-17 PubMed GONUTS page
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