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FB:mud

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) mud ( synonyms: CG12047, KS63, Mud, Mushroom Body Defect, Mushroom body defect, NuMA, mushroom bodies deranged, mushroom body defective )
Protein Name(s) mushroom body defect,
External Links
FB FBgn0002873

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

FB:FBrf0214708
PMID:21855794[1]

IDA: Inferred from Direct Assay

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR008946

F

From FB

GO:0003707

steroid hormone receptor activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR008946

F

From FB

GO:0004784

superoxide dismutase activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001189

F

From FB

GO:0005515

protein binding

FB:FBrf0201141
PMID:17726110[2]

IPI: Inferred from Physical Interaction

FB:FBgn0040080

F

From FB

GO:0005634

nucleus

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR008946

C

From FB

GO:0005813

centrosome

FB:FBrf0201141
PMID:17726110[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0204649
PMID:18433294[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR008946

P

From FB

GO:0006801

superoxide metabolic process

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001189

P

From FB

GO:0007058

spindle assembly involved in female meiosis II

FB:FBrf0192318
PMID:16510791[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016319

mushroom body development

FB:FBrf0090884
PMID:8790424[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016319

mushroom body development

FB:FBrf0128481
PMID:10884435[6]

TAS: Traceable Author Statement

P

From FB

GO:0043401

steroid hormone mediated signaling pathway

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR008946

P

From FB

GO:0045179

apical cortex

FB:FBrf0201141
PMID:17726110[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0045180

basal cortex

FB:FBrf0201141
PMID:17726110[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0046872

metal ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001189

F

From FB

GO:0051233

spindle midzone

FB:FBrf0192318
PMID:16510791[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0055059

asymmetric neuroblast division

FB:FBrf0208429
PMID:19619498[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0055114

oxidation-reduction process

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001189

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Smith NR & Prehoda KE (2011) Robust spindle alignment in Drosophila neuroblasts by ultrasensitive activation of pins. Mol Cell 43: 540-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Nipper RW et al. (2007) Galphai generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts. Proc Natl Acad Sci U S A 104: 14306-11 PubMed GONUTS page
  3. Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
  4. 4.0 4.1 Yu JX et al. (2006) The mushroom body defect gene product is an essential component of the meiosis II spindle apparatus in Drosophila oocytes. Genetics 173: 243-53 PubMed GONUTS page
  5. de Belle JS & Heisenberg M (1996) Expression of Drosophila mushroom body mutations in alternative genetic backgrounds: a case study of the mushroom body miniature gene (mbm). Proc Natl Acad Sci U S A 93: 9875-80 PubMed GONUTS page
  6. Guan Z et al. (2000) Mushroom body defect, a gene involved in the control of neuroblast proliferation in Drosophila, encodes a coiled-coil protein. Proc Natl Acad Sci U S A 97: 8122-7 PubMed GONUTS page
  7. Cabernard C & Doe CQ (2009) Apical/basal spindle orientation is required for neuroblast homeostasis and neuronal differentiation in Drosophila. Dev Cell 17: 134-41 PubMed GONUTS page
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