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FB:mts
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | mts ( synonyms: 5559, CG7109, DmPp2A-28D, ER2-6, MTS/PP2A, Microtubule star, Mts, PP2, PP2A, PP2A 28D, PP2A C, PP2A catalytic subunit, PP2A-C, PP2A(C), PP2A((C)), PP2Ac, PP2a, PP2a 28D, Pp2A, Pp2A-28D, Protein phosphatase 2A at 28D, catalytic subunit C of type 2A protein phosphatase, dPP2A, l(2)02496, l(2)s5286, phosphatase 2A catalytic subunit, protein phosphatase 2A ) | |
| Protein Name(s) | microtubule star, | |
| External Links | ||
| FB | FBgn0004177 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000159 |
protein phosphatase type 2A complex |
FB:FBrf0057179 |
ISS: Inferred from Sequence or Structural Similarity |
C |
From FB |
|||
| GO:0000226 |
microtubule cytoskeleton organization |
FB:FBrf0193166 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000278 |
mitotic cell cycle |
FB:FBrf0192076 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0004722 |
protein serine/threonine phosphatase activity |
FB:FBrf0057179 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0004722 |
protein serine/threonine phosphatase activity |
FB:FBrf0091177 |
IMP: Inferred from Mutant Phenotype |
F |
From FB |
|||
| GO:0004722 |
protein serine/threonine phosphatase activity |
FB:FBrf0123819 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004722 |
protein serine/threonine phosphatase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0076752 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0005737 |
cytoplasm |
FB:FBrf0207940 |
IDA: Inferred from Direct Assay |
C |
From FB |
|||
| GO:0006470 |
protein dephosphorylation |
FB:FBrf0091177 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0006470 |
protein dephosphorylation |
FB:FBrf0123819 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006470 |
protein dephosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0006911 |
phagocytosis, engulfment |
FB:FBrf0191376 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007015 |
actin filament organization |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007051 |
spindle organization |
FB:FBrf0091177 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007059 |
chromosome segregation |
FB:FBrf0192076 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007067 |
mitosis |
FB:FBrf0091177 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007098 |
centrosome cycle |
FB:FBrf0192076 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007155 |
cell adhesion |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007406 |
negative regulation of neuroblast proliferation |
FB:FBrf0208148 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007465 |
R7 cell fate commitment |
FB:FBrf0086675 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003205 |
P |
From FB |
||
| GO:0008360 |
regulation of cell shape |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0009416 |
response to light stimulus |
FB:FBrf0202809 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004784 |
P |
From FB |
||
| GO:0019208 |
phosphatase regulator activity |
FB:FBrf0202809 |
IDA: Inferred from Direct Assay |
F |
From FB |
|||
| GO:0045880 |
positive regulation of smoothened signaling pathway |
FB:FBrf0205418 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0003444 |
P |
From FB |
||
| GO:0045880 |
positive regulation of smoothened signaling pathway |
FB:FBrf0205418 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0004644 |
P |
From FB |
||
| GO:0048477 |
oogenesis |
FB:FBrf0086675 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051225 |
spindle assembly |
FB:FBrf0192076 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0051298 |
centrosome duplication |
FB:FBrf0212030 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0055059 |
asymmetric neuroblast division |
FB:FBrf0209035 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0002121 |
P |
From FB |
||
| GO:0055059 |
asymmetric neuroblast division |
FB:FBrf0209035 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0026192 |
P |
From FB |
||
| GO:0060070 |
canonical Wnt receptor signaling pathway |
FB:FBrf0208588 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0090162 |
establishment of epithelial cell polarity |
FB:FBrf0209035 |
IEP: Inferred from Expression Pattern |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Mayer-Jaekel RE et al. (1992) Molecular cloning and developmental expression of the catalytic and 65-kDa regulatory subunits of protein phosphatase 2A in Drosophila. Mol Biol Cell 3: 287-98 PubMed GONUTS page
- ↑ Viquez NM et al. (2006) The B' protein phosphatase 2A regulatory subunit well-rounded regulates synaptic growth and cytoskeletal stability at the Drosophila neuromuscular junction. J Neurosci 26: 9293-303 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Chen F et al. (2007) Multiple protein phosphatases are required for mitosis in Drosophila. Curr Biol 17: 293-303 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Snaith HA et al. (1996) Deficiency of protein phosphatase 2A uncouples the nuclear and centrosome cycles and prevents attachment of microtubules to the kinetochore in Drosophila microtubule star (mts) embryos. J Cell Sci 109 ( Pt 13): 3001-12 PubMed GONUTS page
- ↑ 5.0 5.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ Mayer-Jaekel RE et al. (1994) Drosophila mutants in the 55 kDa regulatory subunit of protein phosphatase 2A show strongly reduced ability to dephosphorylate substrates of p34cdc2. J Cell Sci 107 ( Pt 9): 2609-16 PubMed GONUTS page
- ↑ Chabu C & Doe CQ (2009) Twins/PP2A regulates aPKC to control neuroblast cell polarity and self-renewal. Dev Biol 330: 399-405 PubMed GONUTS page
- ↑ Stroschein-Stevenson SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol 4: e4 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
- ↑ Wang C et al. (2009) Protein phosphatase 2A regulates self-renewal of Drosophila neural stem cells. Development 136: 2287-96 PubMed GONUTS page
- ↑ 11.0 11.1 Wassarman DA et al. (1996) Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila. Genes Dev 10: 272-8 PubMed GONUTS page
- ↑ 12.0 12.1 Wang N et al. (2008) Role of protein phosphatase 2A in regulating the visual signaling in Drosophila. J Neurosci 28: 1444-51 PubMed GONUTS page
- ↑ 13.0 13.1 Casso DJ et al. (2008) A screen for modifiers of hedgehog signaling in Drosophila melanogaster identifies swm and mts. Genetics 178: 1399-413 PubMed GONUTS page
- ↑ Müller H et al. (2010) Proteomic and functional analysis of the mitotic Drosophila centrosome. EMBO J 29: 3344-57 PubMed GONUTS page
- ↑ 15.0 15.1 15.2 Ogawa H et al. (2009) Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions. J Cell Sci 122: 3242-9 PubMed GONUTS page
- ↑ Zhang W et al. (2009) PR55 alpha, a regulatory subunit of PP2A, specifically regulates PP2A-mediated beta-catenin dephosphorylation. J Biol Chem 284: 22649-56 PubMed GONUTS page
