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FB:msps

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) msps ( synonyms: CG5000, Dis1, MINISPINDLES, MSPS, Mini Spindles, Mini spindles, Mini-spindles, Minispindles, Msps, TOG, XMAP215, anon-WO0140519.136, mini-spindles, minispindles )
Protein Name(s) mini spindles,
External Links
FB FBgn0027948

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000022

mitotic spindle elongation

FB:FBrf0190017
PMID:16303556[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000022

mitotic spindle elongation

FB:FBrf0200397
PMID:17412918[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000922

spindle pole

FB:FBrf0134594
PMID:11258476[3]

NAS: Non-traceable Author Statement

C

From FB

GO:0005515

protein binding

FB:FBrf0137062
PMID:11433296[4]

IPI: Inferred from Physical Interaction

FB:FBgn0026620

F

From FB

GO:0005813

centrosome

FB:FBrf0134594
PMID:11258476[3]

NAS: Non-traceable Author Statement

C

From FB

GO:0005813

centrosome

FB:FBrf0137062
PMID:11433296[4]

TAS: Traceable Author Statement

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0118641

NAS: Non-traceable Author Statement

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0132100
PMID:10908588[5]

ISS: Inferred from Sequence or Structural Similarity

NCBI_gi:2136282

C

From FB

GO:0005875

microtubule associated complex

FB:FBrf0204649
PMID:18433294[6]

IDA: Inferred from Direct Assay

C

From FB

GO:0007017

microtubule-based process

FB:FBrf0132100
PMID:10908588[5]

ISS: Inferred from Sequence or Structural Similarity

NCBI_gi:2136282

P

From FB

GO:0007029

endoplasmic reticulum organization

FB:FBrf0208067
PMID:19303437[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007067

mitosis

FB:FBrf0155485
PMID:12325124[8]

TAS: Traceable Author Statement

P

From FB

GO:0007067

mitosis

FB:FBrf0207149
PMID:18463163[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007143

female meiosis

FB:FBrf0137061
PMID:11433295[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007143

female meiosis

FB:FBrf0155485
PMID:12325124[8]

TAS: Traceable Author Statement

P

From FB

GO:0007344

pronuclear fusion

FB:FBrf0137062
PMID:11433296[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007411

axon guidance

FB:FBrf0211499
PMID:20498300[11]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008017

microtubule binding

FB:FBrf0132100
PMID:10908588[5]

ISS: Inferred from Sequence or Structural Similarity

NCBI_gi:2136282

F

From FB

GO:0015631

tubulin binding

FB:FBrf0201907
PMID:17889670[12]

IDA: Inferred from Direct Assay

F

From FB

GO:0016325

oocyte microtubule cytoskeleton organization

FB:FBrf0180071
PMID:15530399[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031122

cytoplasmic microtubule organization

FB:FBrf0180071
PMID:15530399[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031122

cytoplasmic microtubule organization

FB:FBrf0187508
PMID:15775959[14]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031122

cytoplasmic microtubule organization

FB:FBrf0208067
PMID:19303437[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035371

microtubule plus end

FB:FBrf0201907
PMID:17889670[12]

IDA: Inferred from Direct Assay

C

From FB

GO:0045450

bicoid mRNA localization

FB:FBrf0180071
PMID:15530399[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048477

oogenesis

FB:FBrf0208067
PMID:19303437[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0090063

positive regulation of microtubule nucleation

FB:FBrf0201907
PMID:17889670[12]

IDA: Inferred from Direct Assay

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Goshima G et al. (2005) Length control of the metaphase spindle. Curr Biol 15: 1979-88 PubMed GONUTS page
  2. Goshima G et al. (2007) Genes required for mitotic spindle assembly in Drosophila S2 cells. Science 316: 417-21 PubMed GONUTS page
  3. 3.0 3.1 Gonzalez C & Bornens M (2000) Light, flies and cell division. Workshop: regulation of cell division in Drosophila. EMBO Rep 1: 390-3 PubMed GONUTS page
  4. 4.0 4.1 4.2 Lee MJ et al. (2001) Msps/XMAP215 interacts with the centrosomal protein D-TACC to regulate microtubule behaviour. Nat Cell Biol 3: 643-9 PubMed GONUTS page
  5. 5.0 5.1 5.2 Goldstein LS & Gunawardena S (2000) Flying through the drosophila cytoskeletal genome. J Cell Biol 150: F63-8 PubMed GONUTS page
  6. Hughes JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol 6: e98 PubMed GONUTS page
  7. 7.0 7.1 7.2 Pokrywka NJ et al. (2009) Microtubules, the ER and Exu: new associations revealed by analysis of mini spindles mutations. Mech Dev 126: 289-300 PubMed GONUTS page
  8. 8.0 8.1 Gergely F (2002) Centrosomal TACCtics. Bioessays 24: 915-25 PubMed GONUTS page
  9. Ducat D et al. (2008) Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin. Mol Biol Cell 19: 3097-110 PubMed GONUTS page
  10. Cullen CF & Ohkura H (2001) Msps protein is localized to acentrosomal poles to ensure bipolarity of Drosophila meiotic spindles. Nat Cell Biol 3: 637-42 PubMed GONUTS page
  11. Lowery LA et al. (2010) Parallel genetic and proteomic screens identify Msps as a CLASP-Abl pathway interactor in Drosophila. Genetics 185: 1311-25 PubMed GONUTS page
  12. 12.0 12.1 12.2 Slep KC & Vale RD (2007) Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1. Mol Cell 27: 976-91 PubMed GONUTS page
  13. 13.0 13.1 13.2 Moon W & Hazelrigg T (2004) The Drosophila microtubule-associated protein mini spindles is required for cytoplasmic microtubules in oogenesis. Curr Biol 14: 1957-61 PubMed GONUTS page
  14. Brittle AL & Ohkura H (2005) Mini spindles, the XMAP215 homologue, suppresses pausing of interphase microtubules in Drosophila. EMBO J 24: 1387-96 PubMed GONUTS page
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