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FB:msk

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) msk ( synonyms: 61, CG7935, CIP-61, Corkscrew Interacting Protein-61, DIM-7, Dim-7, Dim7, DmRanBP7, Imp7, Imp7/8, Importin-7, Moleskin, Msk, S(ls)2, dim-7, dim7, diminished-7, importin-7 )
Protein Name(s) moleskin,
External Links
FB FBgn0026252

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000189

MAPK import into nucleus

FB:FBrf0190305
PMID:16308331[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0005488

binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR011989
InterPro:IPR016024

F

From FB

GO:0005634

nucleus

FB:FBrf0134569
PMID:11262240[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005643

nuclear pore

FB:FBrf0127953

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005737

cytoplasm

FB:FBrf0127953

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0005737

cytoplasm

FB:FBrf0134569
PMID:11262240[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005938

cell cortex

FB:FBrf0134569
PMID:11262240[2]

IDA: Inferred from Direct Assay

C

From FB

GO:0005938

cell cortex

FB:FBrf0202255
PMID:17699602[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0006606

protein import into nucleus

FB:FBrf0127953

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0006606

protein import into nucleus

FB:FBrf0134569
PMID:11262240[2]

IDA: Inferred from Direct Assay

P

From FB

GO:0006606

protein import into nucleus

FB:FBrf0167428
PMID:14519396[4]

TAS: Traceable Author Statement

P

From FB

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

FB:FBrf0134569
PMID:11262240[2]

IPI: Inferred from Physical Interaction

FB:FBgn0000382

P

From FB

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

FB:FBrf0134569
PMID:11262240[2]

IPI: Inferred from Physical Interaction

FB:FBgn0003256

P

From FB

GO:0007173

epidermal growth factor receptor signaling pathway

FB:FBrf0134569
PMID:11262240[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0003256

P

From FB

GO:0007474

imaginal disc-derived wing vein specification

FB:FBrf0190305
PMID:16308331[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007476

imaginal disc-derived wing morphogenesis

FB:FBrf0190305
PMID:16308331[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008283

cell proliferation

FB:FBrf0190328
PMID:16540506[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008320

protein transmembrane transporter activity

FB:FBrf0127953

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0008536

Ran GTPase binding

FB:FBrf0128015

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0008565

protein transporter activity

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001494

F

From FB

GO:0008586

imaginal disc-derived wing vein morphogenesis

FB:FBrf0190305
PMID:16308331[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016318

ommatidial rotation

FB:FBrf0190328
PMID:16540506[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0035311

wing cell fate specification

FB:FBrf0190305
PMID:16308331[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042052

rhabdomere development

FB:FBrf0194654
PMID:17110483[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042675

compound eye cone cell differentiation

FB:FBrf0194654
PMID:17110483[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043524

negative regulation of neuron apoptotic process

FB:FBrf0190328
PMID:16540506[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045465

R8 cell differentiation

FB:FBrf0194654
PMID:17110483[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046331

lateral inhibition

FB:FBrf0214518

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048471

perinuclear region of cytoplasm

FB:FBrf0202255
PMID:17699602[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0048749

compound eye development

FB:FBrf0194654
PMID:17110483[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0002573

P

From FB

GO:0048749

compound eye development

FB:FBrf0194654
PMID:17110483[6]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Marenda DR et al. (2006) MAP kinase subcellular localization controls both pattern and proliferation in the developing Drosophila wing. Development 133: 43-51 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Lorenzen JA et al. (2001) Nuclear import of activated D-ERK by DIM-7, an importin family member encoded by the gene moleskin. Development 128: 1403-14 PubMed GONUTS page
  3. 3.0 3.1 James BP et al. (2007) Nuclear localization of the ERK MAP kinase mediated by Drosophila alphaPS2betaPS integrin and importin-7. Mol Biol Cell 18: 4190-9 PubMed GONUTS page
  4. Brower DL (2003) Platelets with wings: the maturation of Drosophila integrin biology. Curr Opin Cell Biol 15: 607-13 PubMed GONUTS page
  5. 5.0 5.1 5.2 Vrailas AD et al. (2006) smoothened and thickveins regulate Moleskin/Importin 7-mediated MAP kinase signaling in the developing Drosophila eye. Development 133: 1485-94 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 6.4 Pepple KL et al. (2007) A genetic screen in Drosophila for genes interacting with senseless during neuronal development identifies the importin moleskin. Genetics 175: 125-41 PubMed GONUTS page
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