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FB:mre11

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) mre11 ( synonyms: 16928, CG16928, MRE11, Mre11 )
Protein Name(s) meiotic recombination 11,
External Links
FB FBgn0020270

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000723

telomere maintenance

FB:FBrf0180053
PMID:15296751[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000723

telomere maintenance

FB:FBrf0180055
PMID:15296753[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0000723

telomere maintenance

FB:FBrf0191425
PMID:16203987[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0004519

endonuclease activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0004837

F

From FB

GO:0004519

endonuclease activity

FB:FBrf0113484

NAS: Non-traceable Author Statement

F

From FB

GO:0004527

exonuclease activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0004837

F

From FB

GO:0004527

exonuclease activity

FB:FBrf0113484

NAS: Non-traceable Author Statement

F

From FB

GO:0005634

nucleus

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR007281

C

From FB

GO:0006289

nucleotide-excision repair

FB:FBrf0113484

NAS: Non-traceable Author Statement

P

From FB

GO:0006302

double-strand break repair

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0004837

P

From FB

GO:0006974

response to DNA damage stimulus

FB:FBrf0208272
PMID:19543366[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016233

telomere capping

FB:FBrf0208278
PMID:19520832[5]

IDA: Inferred from Direct Assay

P

From FB

GO:0030145

manganese ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR007281

F

From FB

GO:0031572

G2/M transition DNA damage checkpoint

FB:FBrf0190707
PMID:16020777[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051276

chromosome organization

FB:FBrf0180053
PMID:15296751[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0051276

chromosome organization

FB:FBrf0180055
PMID:15296753[2]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Bi X et al. (2004) Telomere protection without a telomerase; the role of ATM and Mre11 in Drosophila telomere maintenance. Curr Biol 14: 1348-53 PubMed GONUTS page
  2. 2.0 2.1 Ciapponi L et al. (2004) The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage. Curr Biol 14: 1360-6 PubMed GONUTS page
  3. Bi X et al. (2005) Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance. Proc Natl Acad Sci U S A 102: 15167-72 PubMed GONUTS page
  4. Ravi D et al. (2009) A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet 5: e1000527 PubMed GONUTS page
  5. Gao G et al. (2009) Mre11-Rad50-Nbs complex is required to cap telomeres during Drosophila embryogenesis. Proc Natl Acad Sci U S A 106: 10728-33 PubMed GONUTS page
  6. Bi X et al. (2005) Drosophila ATM and Mre11 are essential for the G2/M checkpoint induced by low-dose irradiation. Genetics 171: 845-7 PubMed GONUTS page
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