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FB:mod(mdg4)

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) mod(mdg4) ( synonyms: BcDNA:GH07769, BcDNA:SD03001, CG15500, CG15501, CG15802, CG18151, CG32491, CG7836, CG7859, CG8076, Doom, E(var)129, E(var)3-93D, E(var)93D, E-(var)3-93D, E-var(3)1, E-var(3)3, Enhancer of variegation 93D, MOD(MDG4), MOD(MDG4)56.3, MOD2.2, Mod(mdg)4, Mod(mdg4), Mod(mdg4)-67.2, Mod(mdg4)2.2, Mod(mdg4)67.2, Modifier of mdg4, Modifier of mdg4 67.2, Modifier67.2, bpd, branch point disrupted, doom, l(3)03852, l(3)L3101, l(3)j2B7, mdg4, mnm, mnn, mod, mod(gypsy), mod(mdg-4), mod(mdg4, mod(mdg4)-67.2, mod(mdg4)67.2, mod2.2, mod(mdg4), modifier mdg4, modifier of mdg4 in meiosis, modifier of midget4, pf-2 )
Protein Name(s) modifier of mdg4,
External Links
FB FBgn0002781

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000785

chromatin

FB:FBrf0083144
PMID:7664338[1]

IMP: Inferred from Mutant Phenotype

C

From FB

GO:0001672

regulation of chromatin assembly or disassembly

FB:FBrf0083144
PMID:7664338[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003682

chromatin binding

FB:FBrf0083144
PMID:7664338[1]

IMP: Inferred from Mutant Phenotype

F

From FB

GO:0005515

protein binding

FB:FBrf0064436
PMID:8248257[2]

IPI: Inferred from Physical Interaction

FB:FBgn0003567

F

From FB

GO:0005634

nucleus

FB:FBrf0115233

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0127028
PMID:10790390[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0151777
PMID:12386928[4]

NAS: Non-traceable Author Statement

C

From FB

GO:0005700

polytene chromosome

FB:FBrf0127028
PMID:10790390[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005700

polytene chromosome

FB:FBrf0205475
PMID:18369369[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0005886

plasma membrane

FB:FBrf0130037
PMID:11024164[6]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0006325

chromatin organization

FB:FBrf0154667

NAS: Non-traceable Author Statement

P

From FB

GO:0006917

induction of apoptosis

FB:FBrf0093116
PMID:9111355[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006917

induction of apoptosis

FB:FBrf0151777
PMID:12386928[4]

TAS: Traceable Author Statement

P

From FB

GO:0006997

nucleus organization

FB:FBrf0151777
PMID:12386928[4]

TAS: Traceable Author Statement

P

From FB

GO:0007060

male meiosis chromosome segregation

FB:FBrf0201774
PMID:17277376[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007141

male meiosis I

FB:FBrf0201774
PMID:17277376[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008195

phosphatidate phosphatase activity

FB:FBrf0130037
PMID:11024164[6]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0008354

germ cell migration

FB:FBrf0130037
PMID:11024164[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0041087

P

From FB

GO:0008354

germ cell migration

FB:FBrf0130037
PMID:11024164[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042981

regulation of apoptotic process

FB:FBrf0093116
PMID:9111355[7]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048477

oogenesis

FB:FBrf0091142
PMID:8978055[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048477

oogenesis

FB:FBrf0127028
PMID:10790390[3]

IMP: Inferred from Mutant Phenotype

P

From FB

colocalizes_with

GO:0000794

condensed nuclear chromosome

FB:FBrf0189927
PMID:16286005[10]

IDA: Inferred from Direct Assay

C

From FB

colocalizes_with

GO:0005730

nucleolus

FB:FBrf0189927
PMID:16286005[10]

IDA: Inferred from Direct Assay

C

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Gerasimova TI et al. (1995) A Drosophila protein that imparts directionality on a chromatin insulator is an enhancer of position-effect variegation. Cell 82: 587-97 PubMed GONUTS page
  2. Dorn R et al. (1993) The enhancer of position-effect variegation of Drosophila, E(var)3-93D, codes for a chromatin protein containing a conserved domain common to several transcriptional regulators. Proc Natl Acad Sci U S A 90: 11376-80 PubMed GONUTS page
  3. 3.0 3.1 3.2 Büchner K et al. (2000) Genetic and molecular complexity of the position effect variegation modifier mod(mdg4) in Drosophila. Genetics 155: 141-57 PubMed GONUTS page
  4. 4.0 4.1 4.2 Pirrotta V (2002) Trans-splicing in Drosophila. Bioessays 24: 988-91 PubMed GONUTS page
  5. Golovnin A et al. (2008) 'Insulator bodies' are aggregates of proteins but not of insulators. EMBO Rep 9: 440-5 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 Read D et al. (2000) Functional studies of the BTB domain in the Drosophila GAGA and Mod(mdg4) proteins. Nucleic Acids Res 28: 3864-70 PubMed GONUTS page
  7. 7.0 7.1 Harvey AJ et al. (1997) Doom, a product of the Drosophila mod(mdg4) gene, induces apoptosis and binds to baculovirus inhibitor-of-apoptosis proteins. Mol Cell Biol 17: 2835-43 PubMed GONUTS page
  8. 8.0 8.1 Soltani-Bejnood M et al. (2007) Role of the mod(mdg4) common region in homolog segregation in Drosophila male meiosis. Genetics 176: 161-80 PubMed GONUTS page
  9. Perrimon N et al. (1996) Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations. Genetics 144: 1681-92 PubMed GONUTS page
  10. 10.0 10.1 Thomas SE et al. (2005) Identification of two proteins required for conjunction and regular segregation of achiasmate homologs in Drosophila male meiosis. Cell 123: 555-68 PubMed GONUTS page
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