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FB:mew

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) mew ( synonyms: CG1771, CT5254, PS1, PS1 integrin, PS1alpha, PSalpha1, Position-specific-1 antigen, Position-specific-antigen-1alpha, aPS1, alpha integrin, alpha-PS1, alpha-PS1-integrin, alpha1 integrin, alpha1Int, alphaPS integrin, alphaPS1, alphaPS1 integrin, alpha((PS1)), alpha((PS1)) subunit of integrin, integrin alphaPS1, l(1)G0429, l(1)G0443, multiple edematous wing )
Protein Name(s) multiple edematous wings,
External Links
FB FBgn0004456

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004872

receptor activity

FB:FBrf0082534
PMID:7750648[1]

IMP: Inferred from Mutant Phenotype

F

From FB

GO:0004872

receptor activity

FB:FBrf0129868
PMID:10908592[2]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0007155

cell adhesion

FB:FBrf0082534
PMID:7750648[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007157

heterophilic cell-cell adhesion

FB:FBrf0129868
PMID:10908592[2]

TAS: Traceable Author Statement

P

From FB

GO:0007160

cell-matrix adhesion

FB:FBrf0129868
PMID:10908592[2]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0007411

axon guidance

FB:FBrf0149077
PMID:12040052[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007414

axonal defasciculation

FB:FBrf0201257
PMID:17537798[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007424

open tracheal system development

FB:FBrf0160886
PMID:12885551[5]

NAS: Non-traceable Author Statement

P

From FB

GO:0007426

tracheal outgrowth, open tracheal system

FB:FBrf0167264
PMID:14570584[6]

TAS: Traceable Author Statement

P

From FB

GO:0007427

epithelial cell migration, open tracheal system

FB:FBrf0144739
PMID:11835274[7]

TAS: Traceable Author Statement

P

From FB

GO:0007427

epithelial cell migration, open tracheal system

FB:FBrf0161023
PMID:12791296[8]

TAS: Traceable Author Statement

P

From FB

GO:0007431

salivary gland development

FB:FBrf0159337
PMID:12742168[9]

TAS: Traceable Author Statement

P

From FB

GO:0007432

salivary gland boundary specification

FB:FBrf0187388
PMID:15950216[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007435

salivary gland morphogenesis

FB:FBrf0207774
PMID:19253394[11]

IGI: Inferred from Genetic Interaction

FB:FBgn0003889

P

From FB

GO:0007475

apposition of dorsal and ventral imaginal disc-derived wing surfaces

FB:FBrf0167428
PMID:14519396[12]

NAS: Non-traceable Author Statement

P

From FB

GO:0007476

imaginal disc-derived wing morphogenesis

FB:FBrf0090466
PMID:8898242[13]

IEP: Inferred from Expression Pattern

P

From FB

GO:0007476

imaginal disc-derived wing morphogenesis

FB:FBrf0090466
PMID:8898242[13]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007476

imaginal disc-derived wing morphogenesis

FB:FBrf0129746
PMID:10936444[14]

TAS: Traceable Author Statement

P

From FB

GO:0007494

midgut development

FB:FBrf0129746
PMID:10936444[14]

TAS: Traceable Author Statement

P

From FB

GO:0007608

sensory perception of smell

FB:FBrf0159056
PMID:12696671[15]

IGI: Inferred from Genetic Interaction

FB:FBgn0003656

P

From FB

GO:0008305

integrin complex

FB:FBrf0124284

NAS: Non-traceable Author Statement

C

From FB

GO:0008305

integrin complex

FB:FBrf0129746
PMID:10936444[14]

ISS: Inferred from Sequence or Structural Similarity

HGNC:6139

C

From FB

GO:0008305

integrin complex

FB:FBrf0129868
PMID:10908592[2]

ISS: Inferred from Sequence or Structural Similarity

C

From FB

GO:0008305

integrin complex

FB:FBrf0167428
PMID:14519396[12]

NAS: Non-traceable Author Statement

C

From FB

GO:0016203

muscle attachment

FB:FBrf0200693
PMID:18039972[16]

IGI: Inferred from Genetic Interaction

FB:FBgn0029830

P

From FB

GO:0016203

muscle attachment

FB:FBrf0200693
PMID:18039972[16]

IGI: Inferred from Genetic Interaction

FB:FBgn0032683

P

From FB

GO:0016337

cell-cell adhesion

FB:FBrf0129746
PMID:10936444[14]

TAS: Traceable Author Statement

P

From FB

GO:0016477

cell migration

FB:FBrf0129746
PMID:10936444[14]

TAS: Traceable Author Statement

P

From FB

GO:0030154

cell differentiation

FB:FBrf0129746
PMID:10936444[14]

TAS: Traceable Author Statement

P

From FB

GO:0035160

maintenance of epithelial integrity, open tracheal system

FB:FBrf0193035
PMID:16720877[17]

IGI: Inferred from Genetic Interaction

FB:FBgn0001250

P

From FB

GO:0048567

ectodermal digestive tract morphogenesis

FB:FBrf0129746
PMID:10936444[14]

TAS: Traceable Author Statement

P

From FB

GO:0050839

cell adhesion molecule binding

FB:FBrf0082534
PMID:7750648[1]

IMP: Inferred from Mutant Phenotype

F

From FB

GO:0050839

cell adhesion molecule binding

FB:FBrf0129868
PMID:10908592[2]

ISS: Inferred from Sequence or Structural Similarity

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Roote CE & Zusman S (1995) Functions for PS integrins in tissue adhesion, migration, and shape changes during early embryonic development in Drosophila. Dev Biol 169: 322-36 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Hynes RO & Zhao Q (2000) The evolution of cell adhesion. J Cell Biol 150: F89-96 PubMed GONUTS page
  3. Stevens A & Jacobs JR (2002) Integrins regulate responsiveness to slit repellent signals. J Neurosci 22: 4448-55 PubMed GONUTS page
  4. Huang Z et al. (2007) Crk-associated substrate (Cas) signaling protein functions with integrins to specify axon guidance during development. Development 134: 2337-47 PubMed GONUTS page
  5. Ribeiro C et al. (2003) Signaling systems, guided cell migration, and organogenesis: insights from genetic studies in Drosophila. Dev Biol 260: 1-8 PubMed GONUTS page
  6. Ghabrial A et al. (2003) Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol 19: 623-47 PubMed GONUTS page
  7. Rosin D & Shilo BZ (2002) Branch-specific migration cues in the Drosophila tracheal system. Bioessays 24: 110-3 PubMed GONUTS page
  8. Uv A et al. (2003) Drosophila tracheal morphogenesis: intricate cellular solutions to basic plumbing problems. Trends Cell Biol 13: 301-9 PubMed GONUTS page
  9. Abrams EW et al. (2003) Constructing an organ: the Drosophila salivary gland as a model for tube formation. Trends Cell Biol 13: 247-54 PubMed GONUTS page
  10. Kolesnikov T & Beckendorf SK (2005) NETRIN and SLIT guide salivary gland migration. Dev Biol 284: 102-11 PubMed GONUTS page
  11. Jattani R et al. (2009) Deficiency screen identifies a novel role for beta 2 tubulin in salivary gland and myoblast migration in the Drosophila embryo. Dev Dyn 238: 853-63 PubMed GONUTS page
  12. 12.0 12.1 Brower DL (2003) Platelets with wings: the maturation of Drosophila integrin biology. Curr Opin Cell Biol 15: 607-13 PubMed GONUTS page
  13. 13.0 13.1 Brabant MC et al. (1996) Distinct spatial and temporal functions for PS integrins during Drosophila wing morphogenesis. Development 122: 3307-17 PubMed GONUTS page
  14. 14.0 14.1 14.2 14.3 14.4 14.5 14.6 Brown NH (2000) Cell-cell adhesion via the ECM: integrin genetics in fly and worm. Matrix Biol 19: 191-201 PubMed GONUTS page
  15. Ayyub C & Paranjape J (2002) Genetic interactions provide evidence for the role of integrins in specifying normal olfactory behavior in Drosophila melanogaster. J Neurogenet 16: 165-74 PubMed GONUTS page
  16. 16.0 16.1 Estrada B et al. (2007) The transmembrane protein Perdido interacts with Grip and integrins to mediate myotube projection and attachment in the Drosophila embryo. Development 134: 4469-78 PubMed GONUTS page
  17. Levi BP et al. (2006) Drosophila talin and integrin genes are required for maintenance of tracheal terminal branches and luminal organization. Development 133: 2383-93 PubMed GONUTS page
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