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FB:mei-9

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) mei-9 ( synonyms: CG3697, DhR1, DmXPF, MEI-9, Rad1p, mei9, meiotic-9, mus(1)110, mus110, xpf/mei-9 )
Protein Name(s) meiotic 9,
External Links
FB FBgn0002707

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000712

resolution of meiotic recombination intermediates

FB:FBrf0155944
PMID:12504024[1]

TAS: Traceable Author Statement

P

From FB

GO:0000712

resolution of meiotic recombination intermediates

FB:FBrf0201675
PMID:17339219[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003677

DNA binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR006166
InterPro:IPR020819

F

From FB

GO:0004520

endodeoxyribonuclease activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

MGI:MGI:1354163

F

From FB

GO:0004520

endodeoxyribonuclease activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q92889

F

From FB

GO:0005515

protein binding

FB:FBrf0155944
PMID:12504024[1]

IPI: Inferred from Physical Interaction

FB:FBgn0002909

F

From FB

GO:0005515

protein binding

FB:FBrf0155944
PMID:12504024[1]

IPI: Inferred from Physical Interaction

FB:FBgn0028434

F

From FB

GO:0005634

nucleus

FB:FBrf0141161

NAS: Non-traceable Author Statement

C

From FB

GO:0006289

nucleotide-excision repair

FB:FBrf0028769
PMID:826452[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006289

nucleotide-excision repair

FB:FBrf0084352
PMID:8647398[4]

ISS: Inferred from Sequence or Structural Similarity

P

From FB

GO:0006289

nucleotide-excision repair

FB:FBrf0130073
PMID:10908583[5]

TAS: Traceable Author Statement

P

From FB

GO:0006289

nucleotide-excision repair

FB:FBrf0141161

NAS: Non-traceable Author Statement

P

From FB

GO:0006298

mismatch repair

FB:FBrf0100533
PMID:9488459[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006298

mismatch repair

FB:FBrf0141161

NAS: Non-traceable Author Statement

P

From FB

GO:0006302

double-strand break repair

FB:FBrf0130073
PMID:10908583[5]

TAS: Traceable Author Statement

P

From FB

GO:0006310

DNA recombination

FB:FBrf0130073
PMID:10908583[5]

TAS: Traceable Author Statement

P

From FB

GO:0006310

DNA recombination

FB:FBrf0141161

NAS: Non-traceable Author Statement

P

From FB

GO:0007095

mitotic cell cycle G2/M transition DNA damage checkpoint

FB:FBrf0212700
PMID:21205937[7]

IGI: Inferred from Genetic Interaction

FB:FBgn0040347

P

From FB

GO:0007131

reciprocal meiotic recombination

FB:FBrf0023919
PMID:4625747[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007131

reciprocal meiotic recombination

FB:FBrf0155944
PMID:12504024[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016321

female meiosis chromosome segregation

FB:FBrf0023919
PMID:4625747[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0043234

protein complex

FB:FBrf0187655
PMID:15944364[9]

IDA: Inferred from Direct Assay

C

From FB

GO:0045132

meiotic chromosome segregation

FB:FBrf0155944
PMID:12504024[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0046982

protein heterodimerization activity

FB:FBrf0128640
PMID:10812334[10]

IPI: Inferred from Physical Interaction

FB:FBgn0028434

F

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 Yildiz O et al. (2002) Drosophila MUS312 interacts with the nucleotide excision repair endonuclease MEI-9 to generate meiotic crossovers. Mol Cell 10: 1503-9 PubMed GONUTS page
  2. Radford SJ et al. (2007) Heteroduplex DNA in meiotic recombination in Drosophila mei-9 mutants. Genetics 176: 63-72 PubMed GONUTS page
  3. Boyd JB et al. (1976) The mei-9 alpha mutant of Drosophila melanogaster increases mutagen sensitivity and decreases excision repair. Genetics 84: 527-44 PubMed GONUTS page
  4. Sekelsky JJ et al. (1995) The Drosophila meiotic recombination gene mei-9 encodes a homologue of the yeast excision repair protein Rad1. Genetics 141: 619-27 PubMed GONUTS page
  5. 5.0 5.1 5.2 Sekelsky JJ et al. (2000) DNA repair in Drosophila: insights from the Drosophila genome sequence. J Cell Biol 150: F31-6 PubMed GONUTS page
  6. Bhui-Kaur A et al. (1998) DNA mismatch repair catalyzed by extracts of mitotic, postmitotic, and senescent Drosophila tissues and involvement of mei-9 gene function for full activity. Mol Cell Biol 18: 1436-43 PubMed GONUTS page
  7. Kondo S & Perrimon N (2011) A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint. Sci Signal 4: rs1 PubMed GONUTS page
  8. 8.0 8.1 Baker BS & Carpenter AT (1972) Genetic analysis of sex chromosomal meiotic mutants in Drosophilia melanogaster. Genetics 71: 255-86 PubMed GONUTS page
  9. Radford SJ et al. (2005) Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossovers. Genetics 170: 1737-45 PubMed GONUTS page
  10. Sekelsky JJ et al. (2000) Nucleotide excision repair endonuclease genes in Drosophila melanogaster. Mutat Res 459: 219-28 PubMed GONUTS page
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