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FB:mei-41
Contents |
| Species (Taxon ID) | Drosophila melanogaster (fruit fly) (taxon:7227) | |
| Gene Name(s) | mei-41 ( synonyms: 4252, ATM-RAD3 related, ATR, CG4252, DmATR, Dmmei41, Drosophila ATR, MEI41, MEI41/FRP1, Mei-41, Mei-41/DATR, Meiotic 41, atr, fs(1)M37, mei-195, mei41, meiP41, meiotic-41, mus(1)103, mus(1)104, mus-103, mus-104, mus103, mus104 ) | |
| Protein Name(s) | meiotic 41, | |
| External Links | ||
| FB | FBgn0004367 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000075 |
cell cycle checkpoint |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000076 |
DNA replication checkpoint |
FB:FBrf0193226 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000077 |
DNA damage checkpoint |
FB:FBrf0127025 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000077 |
DNA damage checkpoint |
FB:FBrf0130073 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0000077 |
DNA damage checkpoint |
FB:FBrf0200034 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0000723 |
telomere maintenance |
FB:FBrf0191425 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0261530 |
P |
From FB |
||
| GO:0001700 |
embryonic development via the syncytial blastoderm |
FB:FBrf0134532 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0001700 |
embryonic development via the syncytial blastoderm |
FB:FBrf0167269 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0004672 |
protein kinase activity |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
F |
From FB |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
FB:FBrf0174215 |
IEA: Inferred from Electronic Annotation |
F |
From FB |
|||
| GO:0006281 |
DNA repair |
FB:FBrf0128122 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0006974 |
response to DNA damage stimulus |
FB:FBrf0208272 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007015 |
actin filament organization |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007088 |
regulation of mitosis |
FB:FBrf0139616 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0000996 |
P |
From FB |
||
| GO:0007088 |
regulation of mitosis |
FB:FBrf0139616 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007093 |
mitotic cell cycle checkpoint |
FB:FBrf0134532 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007095 |
mitotic cell cycle G2/M transition DNA damage checkpoint |
FB:FBrf0212700 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0261530 |
P |
From FB |
||
| GO:0007095 |
mitotic cell cycle G2/M transition DNA damage checkpoint |
FB:FBrf0212700 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007126 |
meiosis |
FB:FBrf0044470 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007131 |
reciprocal meiotic recombination |
FB:FBrf0023919 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007131 |
reciprocal meiotic recombination |
FB:FBrf0128122 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007133 |
meiotic anaphase I |
FB:FBrf0128122 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0007348 |
regulation of syncytial blastoderm mitotic cell cycle |
FB:FBrf0127025 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007349 |
cellularization |
FB:FBrf0134532 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0007444 |
imaginal disc development |
FB:FBrf0134532 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0008360 |
regulation of cell shape |
FB:FBrf0167741 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0009314 |
response to radiation |
FB:FBrf0134532 |
TAS: Traceable Author Statement |
P |
From FB |
|||
| GO:0016301 |
kinase activity |
FB:FBrf0133272 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From FB |
|||
| GO:0016310 |
phosphorylation |
FB:FBrf0132098 |
NAS: Non-traceable Author Statement |
P |
From FB |
|||
| GO:0016321 |
female meiosis chromosome segregation |
FB:FBrf0023919 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0030261 |
chromosome condensation |
FB:FBrf0192205 |
IGI: Inferred from Genetic Interaction |
FB:FBgn0011474 |
P |
From FB |
||
| GO:0045002 |
double-strand break repair via single-strand annealing |
FB:FBrf0200034 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0045003 |
double-strand break repair via synthesis-dependent strand annealing |
FB:FBrf0200034 |
IMP: Inferred from Mutant Phenotype |
P |
From FB |
|||
| GO:0048477 |
oogenesis |
FB:FBrf0044470 |
TAS: Traceable Author Statement |
P |
From FB |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Lee LA & Orr-Weaver TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu Rev Genet 37: 545-78 PubMed GONUTS page
- ↑ Smolik S & Jones K (2007) Drosophila dCBP is involved in establishing the DNA replication checkpoint. Mol Cell Biol 27: 135-46 PubMed GONUTS page
- ↑ 3.0 3.1 Brodsky MH et al. (2000) mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development. Genes Dev 14: 666-78 PubMed GONUTS page
- ↑ Sekelsky JJ et al. (2000) DNA repair in Drosophila: insights from the Drosophila genome sequence. J Cell Biol 150: F31-6 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 LaRocque JR et al. (2007) Drosophila ATR in double-strand break repair. Genetics 175: 1023-33 PubMed GONUTS page
- ↑ Bi X et al. (2005) Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance. Proc Natl Acad Sci U S A 102: 15167-72 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 7.4 Walworth NC (2000) Cell-cycle checkpoint kinases: checking in on the cell cycle. Curr Opin Cell Biol 12: 697-704 PubMed GONUTS page
- ↑ 8.0 8.1 Morrison DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J Cell Biol 150: F57-62 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 McKim KS et al. (2000) mei-41 is required for precocious anaphase in Drosophila females. Chromosoma 109: 44-9 PubMed GONUTS page
- ↑ Ravi D et al. (2009) A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet 5: e1000527 PubMed GONUTS page
- ↑ 11.0 11.1 Kiger AA et al. (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2: 27 PubMed GONUTS page
- ↑ 12.0 12.1 Garner M et al. (2001) mei-41 and bub1 block mitosis at two distinct steps in response to incomplete DNA replication in Drosophila embryos. Curr Biol 11: 1595-9 PubMed GONUTS page
- ↑ 13.0 13.1 Kondo S & Perrimon N (2011) A genome-wide RNAi screen identifies core components of the G₂-M DNA damage checkpoint. Sci Signal 4: rs1 PubMed GONUTS page
- ↑ 14.0 14.1 Perrimon N et al. (1986) X-linked female-sterile loci in Drosophila melanogaster. Genetics 113: 695-712 PubMed GONUTS page
- ↑ 15.0 15.1 Baker BS & Carpenter AT (1972) Genetic analysis of sex chromosomal meiotic mutants in Drosophilia melanogaster. Genetics 71: 255-86 PubMed GONUTS page
- ↑ Sakaguchi A & Steward R (2007) Aberrant monomethylation of histone H4 lysine 20 activates the DNA damage checkpoint in Drosophila melanogaster. J Cell Biol 176: 155-62 PubMed GONUTS page
