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FB:lola

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) lola ( synonyms: BEST:LD03274, BTB-IV, BTB-protein-IV, BcDNA:LD17006, BcDNA:RH31485, BtbIV, CG12052, CG18376, CG18378, CG18379, CG18380, CG18381, CG30012, CG30013, CG30014, LD03274, Lola, Longitudinals lacking, NEST:bs06a08, SGP cluster fusion defects 7, bs06a08.y1, e, eyeful, fus7, l(2)00642, l(2)s3697, longitudinal lacking, longitudinals absent, longitudinals-lacking, misguided, sw59 )
Protein Name(s) longitudinals lacking,
External Links
FB FBgn0005630

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001964

startle response

FB:FBrf0205756
PMID:18713854[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0002121

inter-male aggressive behavior

FB:FBrf0208496
PMID:19519879[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0003676

nucleic acid binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR013087

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0073173
PMID:8050351[3]

ISS: Inferred from Sequence or Structural Similarity

FB:FBgn0003870

F

From FB

GO:0003700

sequence-specific DNA binding transcription factor activity

FB:FBrf0085499

NAS: Non-traceable Author Statement

F

From FB

GO:0005515

protein binding

FB:FBrf0159022
PMID:12538650[4]

IPI: Inferred from Physical Interaction

FB:FBgn0020412

F

From FB

GO:0005634

nucleus

FB:FBrf0073173
PMID:8050351[3]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0085499

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0124022

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0124023

NAS: Non-traceable Author Statement

C

From FB

GO:0005634

nucleus

FB:FBrf0159022
PMID:12538650[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0006355

regulation of transcription, DNA-dependent

FB:FBrf0201045
PMID:18053694[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0006357

regulation of transcription from RNA polymerase II promoter

FB:FBrf0122450

NAS: Non-traceable Author Statement

P

From FB

GO:0007409

axonogenesis

FB:FBrf0073173
PMID:8050351[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007411

axon guidance

FB:FBrf0073173
PMID:8050351[3]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007411

axon guidance

FB:FBrf0124022

NAS: Non-traceable Author Statement

P

From FB

GO:0007411

axon guidance

FB:FBrf0124023

NAS: Non-traceable Author Statement

P

From FB

GO:0007411

axon guidance

FB:FBrf0144825
PMID:11880341[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007411

axon guidance

FB:FBrf0194303
PMID:16979619[7]

IGI: Inferred from Genetic Interaction

FB:FBgn0029123

P

From FB

GO:0007464

R3/R4 cell fate commitment

FB:FBrf0201045
PMID:18053694[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR007087
InterPro:IPR015880

F

From FB

GO:0008406

gonad development

FB:FBrf0213539
PMID:21377458[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0016199

axon midline choice point recognition

FB:FBrf0144825
PMID:11880341[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0003425

P

From FB

GO:0016199

axon midline choice point recognition

FB:FBrf0144825
PMID:11880341[6]

IGI: Inferred from Genetic Interaction

FB:FBgn0005631

P

From FB

GO:0016199

axon midline choice point recognition

FB:FBrf0144825
PMID:11880341[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0019730

antimicrobial humoral response

FB:FBrf0190362
PMID:16163390[9]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0022008

neurogenesis

FB:FBrf0214431

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0031987

locomotion involved in locomotory behavior

FB:FBrf0205756
PMID:18713854[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045467

R7 cell development

FB:FBrf0201045
PMID:18053694[5]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045476

nurse cell apoptotic process

FB:FBrf0194763
PMID:17336958[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045893

positive regulation of transcription, DNA-dependent

FB:FBrf0073173
PMID:8050351[3]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q08605

P

From FB

GO:0048854

brain morphogenesis

FB:FBrf0205756
PMID:18713854[1]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Yamamoto A et al. (2008) Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster. Proc Natl Acad Sci U S A 105: 12393-8 PubMed GONUTS page
  2. Edwards AC et al. (2009) Mutations in many genes affect aggressive behavior in Drosophila melanogaster. BMC Biol 7: 29 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Giniger E et al. (1994) lola encodes a putative transcription factor required for axon growth and guidance in Drosophila. Development 120: 1385-98 PubMed GONUTS page
  4. 4.0 4.1 Zhang W et al. (2003) A developmentally regulated splice variant from the complex lola locus encoding multiple different zinc finger domain proteins interacts with the chromosomal kinase JIL-1. J Biol Chem 278: 11696-704 PubMed GONUTS page
  5. 5.0 5.1 5.2 Zheng L & Carthew RW (2008) Lola regulates cell fate by antagonizing Notch induction in the Drosophila eye. Mech Dev 125: 18-29 PubMed GONUTS page
  6. 6.0 6.1 6.2 6.3 Crowner D et al. (2002) Lola regulates midline crossing of CNS axons in Drosophila. Development 129: 1317-25 PubMed GONUTS page
  7. Girard F et al. (2006) Chromatin immunoprecipitation reveals a novel role for the Drosophila SoxNeuro transcription factor in axonal patterning. Dev Biol 299: 530-42 PubMed GONUTS page
  8. Weyers JJ et al. (2011) A genetic screen for mutations affecting gonad formation in Drosophila reveals a role for the slit/robo pathway. Dev Biol 353: 217-28 PubMed GONUTS page
  9. Kleino A et al. (2005) Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway. EMBO J 24: 3423-34 PubMed GONUTS page
  10. Bass BP et al. (2007) The axon guidance gene lola is required for programmed cell death in the Drosophila ovary. Dev Biol 304: 771-85 PubMed GONUTS page
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