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FB:lark

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) lark ( synonyms: CG8597, LARK, Lark, dLARK )
Protein Name(s) lark,
External Links
FB FBgn0011640

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR012677

F

From FB

GO:0000398

nuclear mRNA splicing, via spliceosome

FB:FBrf0207172
PMID:18981222[1]

IC: Inferred by Curator

GO:0071011
GO:0071013

P

From FB

GO:0003676

nucleic acid binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000504
InterPro:IPR001878
InterPro:IPR013084

F

From FB

GO:0003723

RNA binding

FB:FBrf0180713
PMID:15452872[2]

NAS: Non-traceable Author Statement

F

From FB

GO:0003729

mRNA binding

FB:FBrf0079088

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0003729

mRNA binding

FB:FBrf0129923
PMID:10908586[3]

ISS: Inferred from Sequence or Structural Similarity

F

From FB

GO:0005634

nucleus

FB:FBrf0100603
PMID:9491990[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0005634

nucleus

FB:FBrf0138413
PMID:11560900[5]

IDA: Inferred from Direct Assay

C

From FB

GO:0005737

cytoplasm

FB:FBrf0100603
PMID:9491990[4]

IDA: Inferred from Direct Assay

C

From FB

GO:0007067

mitosis

FB:FBrf0207149
PMID:18463163[6]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007303

cytoplasmic transport, nurse cell to oocyte

FB:FBrf0180713
PMID:15452872[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007562

eclosion

FB:FBrf0159070
PMID:12626480[7]

TAS: Traceable Author Statement

P

From FB

GO:0007623

circadian rhythm

FB:FBrf0065510
PMID:8307324[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0007623

circadian rhythm

FB:FBrf0141665
PMID:11715043[9]

NAS: Non-traceable Author Statement

P

From FB

GO:0008062

eclosion rhythm

FB:FBrf0065510
PMID:8307324[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008062

eclosion rhythm

FB:FBrf0089760
PMID:9120432[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008062

eclosion rhythm

FB:FBrf0141665
PMID:11715043[9]

NAS: Non-traceable Author Statement

P

From FB

GO:0008062

eclosion rhythm

FB:FBrf0149124
PMID:12015613[11]

TAS: Traceable Author Statement

P

From FB

GO:0008062

eclosion rhythm

FB:FBrf0155881
PMID:12486701[12]

TAS: Traceable Author Statement

P

From FB

GO:0008104

protein localization

FB:FBrf0180713
PMID:15452872[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0008270

zinc ion binding

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR001878
InterPro:IPR013084

F

From FB

GO:0009790

embryo development

FB:FBrf0065510
PMID:8307324[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0030036

actin cytoskeleton organization

FB:FBrf0180713
PMID:15452872[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045475

locomotor rhythm

FB:FBrf0149124
PMID:12015613[11]

TAS: Traceable Author Statement

P

From FB

GO:0045804

negative regulation of eclosion

FB:FBrf0065510
PMID:8307324[8]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0045804

negative regulation of eclosion

FB:FBrf0089760
PMID:9120432[10]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048477

oogenesis

FB:FBrf0180713
PMID:15452872[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0071011

precatalytic spliceosome

FB:FBrf0207172
PMID:18981222[1]

IDA: Inferred from Direct Assay

C

From FB

GO:0071013

catalytic step 2 spliceosome

FB:FBrf0207172
PMID:18981222[1]

IDA: Inferred from Direct Assay

C

From FB

NOT

GO:0040011

locomotion

FB:FBrf0159070
PMID:12626480[7]

TAS: Traceable Author Statement

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Herold N et al. (2009) Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Mol Cell Biol 29: 281-301 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 McNeil GP et al. (2004) The Drosophila RNA-binding protein Lark is required for the organization of the actin cytoskeleton and Hu-li tai shao localization during oogenesis. Genesis 40: 90-100 PubMed GONUTS page
  3. Lasko P (2000) The drosophila melanogaster genome: translation factors and RNA binding proteins. J Cell Biol 150: F51-6 PubMed GONUTS page
  4. 4.0 4.1 McNeil GP et al. (1998) A molecular rhythm mediating circadian clock output in Drosophila. Neuron 20: 297-303 PubMed GONUTS page
  5. McNeil GP et al. (2001) Genetic analysis of functional domains within the Drosophila LARK RNA-binding protein. Genetics 159: 229-40 PubMed GONUTS page
  6. Ducat D et al. (2008) Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin. Mol Biol Cell 19: 3097-110 PubMed GONUTS page
  7. 7.0 7.1 Hendricks JC (2003) Invited review: Sleeping flies don't lie: the use of Drosophila melanogaster to study sleep and circadian rhythms. J Appl Physiol 94: 1660-72; discussion 1673 PubMed GONUTS page
  8. 8.0 8.1 8.2 8.3 Newby LM & Jackson FR (1993) A new biological rhythm mutant of Drosophila melanogaster that identifies a gene with an essential embryonic function. Genetics 135: 1077-90 PubMed GONUTS page
  9. 9.0 9.1 Sokolowski MB (2001) Drosophila: genetics meets behaviour. Nat Rev Genet 2: 879-90 PubMed GONUTS page
  10. 10.0 10.1 Newby LM & Jackson FR (1996) Regulation of a specific circadian clock output pathway by lark, a putative RNA-binding protein with repressor activity. J Neurobiol 31: 117-28 PubMed GONUTS page
  11. 11.0 11.1 Panda S et al. (2002) Circadian rhythms from flies to human. Nature 417: 329-35 PubMed GONUTS page
  12. Stanewsky R (2003) Genetic analysis of the circadian system in Drosophila melanogaster and mammals. J Neurobiol 54: 111-47 PubMed GONUTS page
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