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FB:lack

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Contents

Species (Taxon ID) Drosophila melanogaster (fruit fly) (taxon:7227)
Gene Name(s) lack ( synonyms: CG4943, D-smurf, DSmurf, Dsmurf, Lack, Smurf, Smurf ubiquitin ligase, Smurf1, d-smurf, dSmurf, dSmurf1 )
Protein Name(s) lethal with a checkpoint kinase,
External Links
FB FBgn0029006

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001700

embryonic development via the syncytial blastoderm

FB:FBrf0141457
PMID:11703946[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0004842

ubiquitin-protein ligase activity

FB:FBrf0105495

ISS: Inferred from Sequence or Structural Similarity

SGD:S0000927

F

From FB

GO:0004842

ubiquitin-protein ligase activity

FB:FBrf0124765

NAS: Non-traceable Author Statement

F

From FB

GO:0004842

ubiquitin-protein ligase activity

FB:FBrf0126376

NAS: Non-traceable Author Statement

F

From FB

GO:0004842

ubiquitin-protein ligase activity

FB:FBrf0140112

NAS: Non-traceable Author Statement

F

From FB

GO:0005515

protein binding

FB:FBrf0141457
PMID:11703946[1]

IPI: Inferred from Physical Interaction

UniProtKB:P42003

F

From FB

GO:0005515

protein binding

FB:FBrf0160739
PMID:12754252[2]

IPI: Inferred from Physical Interaction

UniProtKB:P42003

F

From FB

GO:0005622

intracellular

FB:FBrf0174215

IEA: Inferred from Electronic Annotation

InterPro:IPR000569

C

From FB

GO:0007179

transforming growth factor beta receptor signaling pathway

FB:FBrf0126376

IGI: Inferred from Genetic Interaction

FB:FBgn0000490

P

From FB

GO:0008101

decapentaplegic signaling pathway

FB:FBrf0141457
PMID:11703946[1]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0010629

negative regulation of gene expression

FB:FBrf0193889
PMID:16780828[3]

IDA: Inferred from Direct Assay

P

From FB

GO:0040008

regulation of growth

FB:FBrf0192304
PMID:17110495[4]

IGI: Inferred from Genetic Interaction

FB:FBgn0002579

P

From FB

GO:0040008

regulation of growth

FB:FBrf0192304
PMID:17110495[4]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0042787

protein ubiquitination involved in ubiquitin-dependent protein catabolic process

FB:FBrf0160739
PMID:12754252[2]

IMP: Inferred from Mutant Phenotype

P

From FB

GO:0048619

embryonic hindgut morphogenesis

FB:FBrf0141457
PMID:11703946[1]

IMP: Inferred from Mutant Phenotype

P

From FB


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Podos SD et al. (2001) The DSmurf ubiquitin-protein ligase restricts BMP signaling spatially and temporally during Drosophila embryogenesis. Dev Cell 1: 567-78 PubMed GONUTS page
  2. 2.0 2.1 Liang YY et al. (2003) dSmurf selectively degrades decapentaplegic-activated MAD, and its overexpression disrupts imaginal disc development. J Biol Chem 278: 26307-10 PubMed GONUTS page
  3. Anderson J et al. (2006) Regulation of the retinal determination gene dachshund in the embryonic head and developing eye of Drosophila. Dev Biol 297: 536-49 PubMed GONUTS page
  4. 4.0 4.1 Tyler DM et al. (2007) Genes affecting cell competition in Drosophila. Genetics 175: 643-57 PubMed GONUTS page
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